GRADE & PURITYRecombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.0.5 mg/mL
ExactAb™, Validated, Recombinant, 0.5 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rabbit anti Human HMGCR Antibody, Recombinant, could be used for WB and so on.
Specifications
Product Name
Recombinant HMGCR Antibody - Primary antibody, specific to HMGCR, Rabbit IgG
Synonyms
EC 1.1.1.34 | HMG-CoA reductase | 3 hydroxy 3 methylglutaryl CoA reductase | 3 hydroxy 3 methylglutaryl Coenzyme A reductase | 3 hydroxymethylglutaryl CoA reductase | 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) | 3-hydroxy-3-methylglutaryl-coenzyme A
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.5 mg/mL
Biochemical and Physiological Mechanisms
This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.
Host species
Rabbit
Specificity
HMGCR
Immunogen
A synthetic peptide derived from human HMGCR (AA 448-462)
Positive Control
WB: K562, HeLa, MCF7, NIH/3T3 and C6 cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Concentration
0.5 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant HMGCR Antibody (Ab108327) - Western Blot All lanes: Recombinant HMGCR Antibody (Ab108327) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 97 kDa Observed band size: 102 kDa Exposure time: 35.0 s
Recombinant HMGCR Antibody (Ab108327) - Western Blot All lanes: Recombinant HMGCR Antibody (Ab108327) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 97 kDa Observed band size: 102 kDa Exposure time: 20.0 s
Application
Application
Dilution info
WB
1/1000
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
1.Mei-Xin Li, Yiqing Yang, Qiuye Zhao, Yue Wu, Lei Song, Haiyan Yang, Ming He, Hongying Gao, Bao-Liang Song, Jie Luo, Yu Rao. (2020) Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase. JOURNAL OF MEDICINAL CHEMISTRY, [PMID:32321253][10.1021/acs.jmedchem.0c00339]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
Reviews
Customer Reviews
Need help choosing the grade?
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
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