What is the best way to choose between the different clone numbers of CD4?
What is the best way to choose between the different clone numbers of CD4?
posted this at Jun 9, 2025 Updated at Sep 12, 2024
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What is the best way to choose between the different clone numbers of CD4?
CD4 [SK3] and CD4 [RM4-5] are used for immunophenotyping cytokines. This is because (1) PMA stimulation leads to endocytosis of CD4, and CD4 clones SK3 and RM4-5 have less effect on endocytosis. (ii) Samples need to be fixed when detecting cytokines, and the CD4-binding domains of SK3 and RM4-5 are less affected by fixatives.
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