NKG2D/CD314 Rat mAb - Primary antibody, specific to NKG2D/CD314, Rat IgG1

Cat. No.: Ab118155

GRADE & PURITY Carrier Free, Validated, Azide Free, PBS Only, ≥95%(SDS-PAGE), See COA

Application

Animal Model, Blocking, Flow Cytometry, Functional Assay

Host species

Rat

Reactive species

Mouse

Isotype

Rat IgG1

Clone Number

CX5

Conjugation

Unconjugated

Overview

Rat anti Mouse NKG2D/CD314 Antibody, Monoclonal (CX5), could be used for in vivo NKG2D blockade, in vitro NKG2D blockade, Flow and so on.
Application:
in vivo NKG2D blockade: Use at an assay dependent concentration.
in vitro NKG2D blockade: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
Protein Function
Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

Specifications

Product Name

NKG2D/CD314 Rat mAb - Primary antibody, specific to NKG2D/CD314, Rat IgG1

Synonyms

Nkg2d | D6H12S2489E | CD314 antigen | CD314 | D12S2489E | FLJ17759 | FLJ75772 | Killer cell lectin-like receptor subfamily K member 1 | killer cell lectin-like receptor subfamily K, member 1 | KLR | KLRK1 | NK cell receptor D | NKG2-D type II integral mem

Specifications & Purity

Carrier Free, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA

Host species

Rat

Specificity

NKG2D/CD314

Immunogen

Purified mouse NKG2D

Conjugation

Unconjugated

Grade

Azide Free, Carrier Free, PBS Only, Validated

Isotype

Rat IgG1

Light Chain Type

kappa

SDS-PAGE

150 kDa

Purification Method

Protein G purified

Concentration

See COA

Storage and Shipping

Shape

Liquid

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice,Do not freeze

Stability And Storage

Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Application

• Application: Dilution info
• Flow Cytometry:

  Use at an assay dependent concentration.

• in vivo NKG2D blockade:

  Use at an assay dependent concentration.;

• in vitro NKG2D blockade:

  Use at an assay dependent concentration.

Associated Targets(Human)

CASC3 Tbio Protein CASC3 (0 Activities)

Discover Target: CASC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KLRK1 Tbio NKG2-D type II integral membrane protein (0 Activities)

Discover Target: KLRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)