Recombinant Homer1 Antibody - Primary antibody, specific to HOMER1, Rabbit IgG

Cat. No.: Ab108509

GRADE & PURITY Recombinant, Validated, ExactAb™, See COA

Application

WB

Host species

Rabbit

Reactive species

Human, Mouse, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Overview

Rabbit anti Human Homer1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function:
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

Specifications

Product Name

Recombinant Homer1 Antibody - Primary antibody, specific to HOMER1, Rabbit IgG

Synonyms

HOMER1 | HOMER | SYN47 | Ves-1 | HOMER1A | HOMER1B | HOMER1C | HOME1_HUMAN antibody | Homer antibody | HOMER 1A antibody | HOMER 1B antibody | HOMER 1C antibody | Homer homolog 1 (Drosophila) antibody | homer homolog 1 antibody | Homer protein homolog 1 a

Specifications & Purity

Recombinant, ExactAb™, Validated, See COA

Host species

Rabbit

Specificity

HOMER1

Immunogen

A synthetic peptide derived from human Homer1 (AA 101-220)

Positive Control

WB: Mouse brain, Rat heart, HeLa, Hep G2, SK-N-SH, NIH/3T3 and C6 lysates.

Conjugation

Unconjugated

Grade

ExactAb™, Recombinant, Validated

Isotype

Rabbit IgG

Light Chain Type

kappa

SDS-PAGE

150 kDa

Purification Method

Protein A purified

Concentration

See COA

Storage and Shipping

Shape

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Application

• Application: Dilution info
• WB:

  1/500-1/2000 ;

Associated Targets(Human)

HOMER1 Tbio Homer protein homolog 1 (0 Activities)

Discover Target: HOMER1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)