Recombinant TXNRD1 Antibody - Primary antibody, specific to TXNRD1, Rabbit IgG

Cat. No.: Ab133101
AVAILABLE TO ORDER
GRADE & PURITY Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. 0.7 mg/mL
Application
IF/ICC, IHC, WB
Host species
Rabbit
Reactive species
Human, Mouse
Isotype
Rabbit IgG
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μl
Ab133101-10μl
2
$99.90
50μl
Ab133101-50μl
1
$259.90
100μl
Ab133101-100μl
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$419.90
1ml
Ab133101-1ml
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$3,399.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

ExactAb™, Validated, Recombinant, 0.7 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Rabbit anti Human TXNRD1 Antibody, Recombinant, could be used for WB, IHC, ICC/IF and so on.
Application
· WB: 1/500-1/1000
· IHC: 1/50-1/100
· ICC/IF: 1/50-1/200
Protein Function
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Specifications

Product Name
Recombinant TXNRD1 Antibody - Primary antibody, specific to TXNRD1, Rabbit IgG
Synonyms
EC 1.8.1.9 | Gene associated with retinoic and IFN-induced mortality 12 protein | Gene associated with retinoic and interferon-induced mortality 12 protein | GRIM-12 | KM-102-derived reductase-like factor | Thioredoxin reductase TR1 | TR | cytoplasmic ant
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.7 mg/mL
Host species
Rabbit
Specificity
TXNRD1
Immunogen
Recombinant full length protein (Human).
Positive Control
WB: K562, Hep G2, Jurkat, LNCaP, NIH/3T3 and C6 cell lysates. IHC: Human lung cancer tissues. ICC/IF: HeLa cells.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen affinity purified
Concentration
0.7 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Recombinant TXNRD1 Antibody (Ab133101) - Western Blot
All lanes: Recombinant TXNRD1 Antibody (Ab133101) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 71 kDa
Observed band size: 55, 61 kDa
Exposure time: 21.3 s

Recombinant TXNRD1 Antibody (Ab133101) - Western Blot
All lanes: Recombinant TXNRD1 Antibody (Ab133101) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 71 kDa
Observed band size: 55 kDa
Exposure time: 10.5 s

Recombinant TXNRD1 Antibody (Ab133101) - IF/ICC
Immunocytochemistry analysis of TXNRD1 (green) in HeLa using Recombinant TXNRD1 Antibody (Ab133101), and cells were counterstained with DAPI (blue).

Recombinant TXNRD1 Antibody (Ab133101) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Recombinant TXNRD1 Antibody (Ab133101). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application
ApplicationDilution info
WB

1/500-1/1000

IF/ICC

1/50-1/200

IHC

1/50 - 1/100

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TXNRD1 Tclin Thioredoxin reductase 1 (99 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303480Certificate of AnalysisMar 21, 2024 Ab133101
ZJ24F0303479Certificate of AnalysisMar 21, 2024 Ab133101
Documents & Articles
Citations of This Product
References
1. Peng Zhu, Jianqiang Qian, Zhongyuan Xu, Chi Meng, Ji Liu, Wenpei Shan, Weizhong Zhu, Yongjun Wang, Yumin Yang, Wei Zhang, Yanan Zhang, Yong Ling.  (2020)  Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling.  JOURNAL OF NATURAL PRODUCTS,      [PMID:33026807] [10.1021/acs.jnatprod.0c00599]
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide →

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