Is it possible to use the vortex shaker to help the lyophilized powder fully dissolve?

Is it possible to use the vortex shaker to help the lyophilized powder fully dissolve?

For the recombinant protein, it has a certain spatial structure to achieve the best activity. During the dissolution process, do not use the vortex shaker to shake rapidly, otherwise the activity of cytokines will be affected. It is recommended to gently blow and mix with the gun head or gently invert and mix.