Carrier Free,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE),See COA Azide Free,Carrier Free,PBS Only,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Do not freeze Ships Wet ice,Do not freeze Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Rat anti Mouse IL-12 p40 Antibody, Monoclonal (C17.8), could be used for in vivo IL-12p40 neutralization, p40 affinity chromatography, IP, ELISA, Flow, WB and so on.
Application:
in vivo IL-12p40 neutralization: Use at an assay dependent concentration.
p40 affinity chromatography: Use at an assay dependent concentration.
IP: Use at an assay dependent concentration.
ELISA: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
Protein Function
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
IL-12 p40 Rat mAb (Ab109858) - ELISA
Immobilized Recombinant Mouse IL-12/IL-23 p40 Monomer protein (rp154137) at 1.0 μg/mL can bind IL-12 p40 Rat mAb (Ab109858) with the EC50 of 13.88 ng/mL.
| Application | Dilution info |
|---|---|
| WB | Use at an assay dependent concentration. |
| IP | Use at an assay dependent concentration. |
| Flow Cytometry | Use at an assay dependent concentration. |
| ELISA | Use at an assay dependent concentration. |
| in vivo IL-12p40 neutralization | Use at an assay dependent concentration. |
| p40 affinity chromatography | Use at an assay dependent concentration. |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F1012734 | Certificate of Analysis | May 20, 2026 | Ab109858 |
| ZJ24F1012735 | Certificate of Analysis | May 20, 2026 | Ab109858 |
| ZJ24F1012736 | Certificate of Analysis | May 20, 2026 | Ab109858 |
| ZJ26F0433765 | Certificate of Analysis | Apr 02, 2026 | Ab109858 |
| ZJ26F0433764 | Certificate of Analysis | Apr 02, 2026 | Ab109858 |
| ZJ26F0433763 | Certificate of Analysis | Apr 02, 2026 | Ab109858 |
| ZJ26F0433762 | Certificate of Analysis | Apr 02, 2026 | Ab109858 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Carrier Free grade guide → View Validated grade guide → View Azide Free grade guide → View PBS Only grade guide →
