Pertuzumab (anti-HER2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB2/HER2/CD340, >95%, Human IgG1, Antibody of erb-b2 receptor tyrosine kinase 2, Antibody of erb-b2 receptor tyrosine kinase 2

CAS: 380610-27-5 Cat. No.: P412000 PubChem CID: 5484725
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human, Mouse, Rat
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
P412000-100μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$97.90
1mg
P412000-1mg
3
$480.90
5mg
P412000-5mg
1
$949.90
10mg
P412000-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$1,459.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Pertuzumab, a humanized IgG1 monoclonal antibody, is a HER2 dimerization inhibitor. It can be used in the study of metastatic HER2 positive breast cancer.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Pertuzumab (anti-HER2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB2/HER2/CD340, >95%, Human IgG1, Antibody of erb-b2 receptor tyrosine kinase 2
Synonyms
2-Butanol, 1-[(2, 3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, [R-(R*, S*)]- | Q27078025 | (2R, 3S)-3-(isopropylamino)-1-[(7-methyl-2, 3-dihydro-1H-inden-4-yl)oxy]butan-2-ol | DTXSID401118341 | SCHEMBL8027938 | (2R, 3S)-1-[(7-methyl-2, 3-dih
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species
Human
Specificity
ERBB2/HER2/CD340
Application
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
INHIBITOR
Mechanism of action
Antibody of erb-b2 receptor tyrosine kinase 2
Antibody Type
Primary antibody
Clonality
Recombinant
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
145.44 kDa
Purification Method
Protein A purified
Purity
>95%
Source
CHO supernatant
Concentration
See COA
CAS
380610-27-5
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Pertuzumab (anti-HER2) (P412000) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling HER2 (red) with Pertuzumab (anti-HER2) (P412000). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Pertuzumab (anti-HER2) (P412000) - SEC
The purity of Pertuzumab (anti-HER2) (P412000) is more than 95% verified by HPLC.

Pertuzumab (anti-HER2) (P412000) - ELISA
Immobilized HER2-23-652-his at 2 μg/mL can bind Pertuzumab (anti-HER2) (P412000) with the EC₅₀ of 13.75 ng/mL.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassIndanes
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentIndanes
Alternative Parents Alkyl aryl ethers  Secondary alcohols  1,2-aminoalcohols  Dialkylamines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Indane - Alkyl aryl ether - 1,2-aminoalcohol - Secondary alcohol - Secondary aliphatic amine - Ether - Secondary amine - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organopnictogen compound - Amine - Organic oxygen compound - Alcohol - Aromatic homopolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as indanes. These are compounds containing an indane moiety, which consists of a cyclopentane fused to a benzene ring.
External Descriptors aromatic ether - secondary alcohol - secondary amino compound - indanes
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRB2 Tclin Beta-2 adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Epidermal growth factor receptor and ErbB2 (HER1 and HER2) (186 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Epidermal growth factor receptor (487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin FASN/HER2 (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
ZJ24F1215935Certificate of AnalysisDec 24, 2024 P412000
ZJ24F1215934Certificate of AnalysisDec 24, 2024 P412000
ZJ23F0800951Certificate of AnalysisSep 04, 2023 P412000
ZJ23F0800952Certificate of AnalysisSep 04, 2023 P412000
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

Related Products

Trastuzumab (anti-HER2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB2/HER2/CD340, >95%, Human IgG1, Antibody of erb-b2 receptor tyrosine kinase 2
Mouse Anti-Human IgM Antibody - Secondary antibody, for ELISA various applications, from Human, generated in Mouse, IgG1
Mouse Anti-Human IgG H&L (HRP) - Secondary antibody, for ELISA various applications, from Human, generated in Mouse, IgG1
Goat Anti-Human IgG H&L (HRP) - Secondary antibody, for WB,ELISA,IHC various applications, from Human, generated in Goat, IgG
Mouse Anti-Human IgG Antibody - Secondary antibody, for ELISA,CLIA various applications, from Human, generated in Rat, IgG1
Human IgG - Isotype Control Antibody, for WB,CLIA,LF,EIA,PRTIA various applications, generated in Human, >95%, IgG
Margetuximab (anti-HER2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, from Human, specific to ErbB2, >95%, Human IgG1, Antibody of erb-b2 receptor tyrosine kinase 2
Goat Anti-Human IgG Antibody - Secondary antibody, ≥ 95%
Mouse Anti-Human IgA H&L Antibody - Secondary antibody, Mouse IgG1
Goat Anti-Human IgG (HRP) - Secondary antibody
Goat Anti-Human IgG (Biotin) - Secondary antibody
Goat Anti-Human IgG (Cy5) - Secondary antibody
Goat Anti-Human IgG (APC) - Secondary antibody
Goat Anti-Human IgG (PE) - Secondary antibody
Goat Anti-Human IgG (TRITC) - Secondary antibody
Goat Anti-Human IgG (FITC) - Secondary antibody
Mouse Anti-Human IgE epsilon chain Antibody - Secondary antibody
Goat Anti-Human IgG Fc Antibody - Secondary antibody, Goat IgG
Gancotamab (anti-HER2) - Primary antibody, specific to ERBB2, Human IgG1, BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent
Human IgG2-Kappa - Isotype Control Antibody, Human IgG2
Human IgG3-kappa - Isotype Control Antibody, Human IgG3
Human IgG1-kappa, anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD, Human IgG1
Human IgG4-kappa - Isotype Control Antibody, IgG4
Goat Anti-Human IgG (AF647) - Secondary antibody, IgG
Goat Anti-Human IgG (AF405) - Secondary antibody, IgG
Human IgG (FITC) - Isotype Control Antibody, IgG
Human IgG (APC) - Isotype Control Antibody, IgG
Human IgG (PE) - Isotype Control Antibody, IgG
Human IgG1(P331S/E430G)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(P331S/E430G)
Human IgG1(D265A/N297A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(D265A/N297A)
Human IgG1(K409R/E356D/M358L)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(K409R/E356D/M358L)
Human IgG1(P329G/E356D/M358L)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(P329G/E356D/M358L)
Human IgG1(F405L)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(F405L)
Human IgG1(N297Q)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(N297Q)
Human IgG (Biotin) - Isotype Control Antibody, IgG
Human IgG1(N297S)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(N297S)
Human IgG1(E233A/L235A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(E233A/L235A)
Human IgG1(K214R/N297A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(K214R/N297A)
Human IgG1(K214R/L234A/L235A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(K214R/L234A/L235A)
Human IgG1(N297A/E356D/M358L)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(N297A/E356D/M358L)
Human IgG1(L234F/L235E)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(L234F/L235E)
Human IgG1(D265A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(D265A)
Human IgG1(K214R/L234F/L235E/P331S)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(K214R/L234F/L235E/P331S)
Human IgG1(K214R/E356D/M358L)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(K214R/E356D/M358L)
Human IgG1(L234A/L235A/G237A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(L234A/L235A/G237A)
Human IgG1(L234A/L235A/F405L)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(L234A/L235A/F405L)
Human IgG1(D270N)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(D270N)
Human IgG4(S228P)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG4(S228P)
Human IgG1(N297A)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG1(N297A)
Human IgG4(S228P/L235E/P329G)-kappa, anti-HEL - Isotype Control Antibody, specific to HEL, Human IgG4(S228P/L235E/P329G)
Human IgG1-lambda1, anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD, Human IgG1
Human IgG1-lambda2, anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD, Human IgG1
Disitamab (anti-ERBB2) - Primary antibody, specific to ERBB2, Human IgG1
Timigutuzumab (anti-ERBB2) - Primary antibody, specific to ERBB2, Human IgG1
Goat Anti-Human IgG (AF555) - Secondary antibody, IgG
Coprelotamab (anti-ERBB2) - Primary antibody, specific to ERBB2, Human IgG1
Human IgG1-kappa (AF405), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Human IgG1-kappa (AF647), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Human IgG1-kappa (APC), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Human IgG1-kappa (Biotin), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Human IgG1-kappa (AF700), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Human IgG1-kappa (FITC), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Human IgG1-kappa (AF555), anti-Spike RBD - Isotype Control Antibody, specific to Spike RBD
Centrose patent anti-dysadherin (anti-Dysadherin) - Primary antibody, specific to FXYD5
Human IgG (AF647) - Isotype Control Antibody
Human IgG (AF488) - Isotype Control Antibody
Human IgG (AF700) - Isotype Control Antibody
Human IgG (AF405) - Isotype Control Antibody
Goat Anti-Human IgG (AF488) - Secondary antibody
Goat Anti-Human IgG Fc (Cy5) - Secondary antibody
Goat Anti-Human IgG Fc (AF555) - Secondary antibody, specific to Human IgG Fc
Goat Anti-Human IgG Fc (TRITC) - Secondary antibody
Goat Anti-Human IgG Fc (AF700) - Secondary antibody, specific to Human IgG Fc
Goat Anti-Human IgG Fc (AF405) - Secondary antibody
Goat Anti-Human IgG Fc (Biotin) - Secondary antibody, specific to Human IgG Fc
Goat Anti-Human IgG Fc (AF647) - Secondary antibody
Goat Anti-Human IgG Fc (FITC) - Secondary antibody, specific to Human IgG Fc
Human IgG (AF555) - Isotype Control Antibody

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.