HEPPS - for cell culture, ≥99.5%(T), used for EPPS may be used as a buffer solution to stabilize the pH in sea water samples during the titration experiments. various applications , CAS No.16052-06-5

CAS: 16052-06-5 Cat. No.: H110901 Molecular Weight: 252.33 Beilstein Registry Number: 3957385 EC Number: 240-198-8

GRADE & PURITY for Cell culture, ≥99.5%(T)

Synonyms

2-Amino-cyclopentanecarboxylic acid | 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonicAcid | N-(2-Hydroxyethyl)piperazine-N'-(3-propanesulfonic acid) | 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid | A810147 | F20313 | UNII-8JN5PQW99C | EPPS

Storage

Room temperature

Shipped In

Normal

Overview

EPPS or 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (HEPPS) is a zwitterionic buffer substance from the group of good buffers.It effectively maintains constant pH in a solution, which is necessary for many biological and biochemical reactions. EPPS buffer is widely used in cell culture experiments and biological research.

Specifications

Synonyms

2-Amino-cyclopentanecarboxylic acid | 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonicAcid | N-(2-Hydroxyethyl)piperazine-N'-(3-propanesulfonic acid) | 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid | A810147 | F20313 | UNII-8JN5PQW99C | EPPS

Specifications & Purity

for cell culture, ≥99.5%(T)

Application

EPPS may be used as a buffer solution to stabilize the pH in sea water samples during the titration experiments.

Storage

Room temperature

Shipped In

Normal

Grade

for Cell culture

Purity

≥99.5%(T)

Names and Identifiers

• Canonical Smiles: C1CN(CCN1CCCS(=O)(=O)O)CCO
• IUPAC Name: 3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
• InChIKey: OWXMKDGYPWMGEB-UHFFFAOYSA-N
• INCHI: 1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)
• Isomeric SMILES: C1CN(CCN1CCCS(=O)(=O)O)CCO
• WGK Germany: 3
• RTECS: TM2649130
• Molecular Weight: 252.33
• Beilstein: 3957385
• Reaxy-Rn: 3957385
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3957385&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Diazinanes
      • Subclass Piperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: Not available
• Direct Parent: N-alkylpiperazines
• Alternative Parents: Sulfonyls Organosulfonic acids Alkanesulfonic acids Trialkylamines 1,2-aminoalcohols Azacyclic compounds Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: N-alkylpiperazine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - 1,2-aminoalcohol - Tertiary amine - Tertiary aliphatic amine - Azacycle - Alkanolamine - Alcohol - Organic nitrogen compound - Primary alcohol - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Amine - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as n-alkylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an alkyl group.
• External Descriptors: N-(2-hydroxyethyl)piperazine - N-(sulfoalkyl)piperazine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Light sensitive.
• Melt Point(°C): 237-239°C
• Molecular Weight: 252.330 g/mol
• XLogP3: -3.600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 252.114 Da
• Monoisotopic Mass: 252.114 Da
• Topological Polar Surface Area: 89.500 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 280.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Shuofeng Liang, Shuxiu Li, Chenrui Yuan, Dachuan Zhang, Jiahui Chen, Si Wu.  (2023)  Polyacrylate Backbone Promotes Photoinduced Reversible Solid-To-Liquid Transitions of Azobenzene-Containing Polymers.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.2c02002]