CD278/ICOS Armenian Hamster mAb (Biotin) - Primary antibody, specific to ICOS, Armenian Hamster IgG

Cat. No.: Ab185167

GRADE & PURITY Validated, ExactAb™, 0.5 mg/mL

Application

Flow Cytometry

Host species

Armenian hamster

Reactive species

Human, Mouse, Rat

Isotype

Armenian Hamster IgG

Clone Number

C398.4A

Conjugation

Biotin

Overview

Armenian Hamster anti Human CD278/ICOS Antibody, Monoclonal (C398.4A), could be used for Flow and so on.

Specifications

Product Name

CD278/ICOS Armenian Hamster mAb (Biotin) - Primary antibody, specific to ICOS, Armenian Hamster IgG

Synonyms

Activation-inducible lymphocyte immunomediatory molecule | AILIM | AILIMCD278 | CD278 antigen | CD278 | CRP-1 | CVID1 | ICOS | inducible costimulator | inducible T-cell costimulator | inducible T-cell co-stimulator | MGC39850 | Activation inducible lympho

Specifications & Purity

ExactAb™, Validated, 0.5 mg/mL

Biochemical and Physiological Mechanisms

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient int

Host species

Armenian hamster

Specificity

ICOS

Immunogen

Mouse T cell clone D10.G4.1

Positive Control

Flow: Human peripheral blood lymphocytes.

Conjugation

Biotin

Grade

ExactAb™, Validated

Isotype

Armenian Hamster IgG

Purification Method

Protein G purified

Concentration

0.5 mg/mL

Storage and Shipping

Storage

Store at 2-8°C,Protected from light,Do not freeze

Shipped In

Wet ice,Do not freeze

Stability And Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Images

Flow Cytometry: CD278/ICOS Armenian Hamster mAb (Biotin) (Ab185167)

CD278/ICOS Armenian Hamster mAb (Biotin) (Ab185167) - Flow Cytometry
Human peripheral blood lymphocytes treated with 10 μg/mL PHA for 3 days are stained with CD278/ICOS Armenian Hamster mAb (Biotin) (Ab185167) (right panel) at 0.2μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Left panel - Armenian Hamster IgG (Biotin) (Ab191741).

Flow Cytometry: CD278/ICOS Armenian Hamster mAb (Biotin) (Ab185167)

CD278/ICOS Armenian Hamster mAb (Biotin) (Ab185167) - Flow Cytometry
Human peripheral blood lymphocytes treated with 10 μg/mL PHA for 3 days are stained with CD278/ICOS Armenian Hamster mAb (Biotin) (Ab185167) (right panel) at 0.2μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Blue - Armenian Hamster IgG (Biotin) (Ab191741). Black - Unlabelled control, cells without incubation with primary antibody. Untreated lymphocytes were used as control (left panel).

Application

• Application: Dilution info
• Flow Cytometry:

  ≤0.3 μg/test, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume ;

Associated Targets(Human)

ICOS Tbio Inducible T-cell costimulator (0 Activities)

Discover Target: ICOS

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action