In Alzheimer’s disease models, cholinergic detection should not focus only on measuring acetylcholine or acetylcholinesterase separately. The key is to assess the relationship among neurotransmitter levels, enzyme activity changes, cholinergic neuronal injury, and inflammatory responses. When ...
Cholinesterase detection systems are mainly used to measure the activities of acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and total cholinesterase (ChE). The differences among detection methods are mainly reflected in substrate type, signal generation mode, readout format, ability ...
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