Microglia-containing human brain organoids (MC-HBOs) integrate neural cells, glial cells, and resident immune cells of the central nervous system within a three-dimensional culture system and can be used to analyze the roles of microglia in brain development, neuroinflammation, and ...
Topic
Microglia
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
3 resources · protocols, FAQs & articles
Neuroinflammation is an inflammatory response formed in the nervous system under conditions such as infection, injury, metabolic stress, abnormal protein deposition, or immune imbalance. Its core lies in the dynamic imbalance among microglia, astrocytes, peripheral immune cells, the blood-brain ...
In Alzheimer’s disease models, cholinergic detection should not focus only on measuring acetylcholine or acetylcholinesterase separately. The key is to assess the relationship among neurotransmitter levels, enzyme activity changes, cholinergic neuronal injury, and inflammatory responses. When ...
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Techniques often explored alongside immunological experiments.