Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Enavatuzumab (anti-TWEAKR) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab (anti-TWEAKR) induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab (anti-TWEAKR) can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab (anti-TWEAKR) inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Enavatuzumab (anti-TWEAKR) (Ab183422) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling TWEAKR (red) with Enavatuzumab (anti-TWEAKR) (Ab183422). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Enavatuzumab (anti-TWEAKR) (Ab183422) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling TWEAKR (red) with Enavatuzumab (anti-TWEAKR) (Ab183422). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Enavatuzumab (anti-TWEAKR) (Ab183422) - SEC
The purity of Enavatuzumab (anti-TWEAKR) (Ab183422) is more than 95% verified by HPLC.
Enavatuzumab (anti-TWEAKR) (Ab183422) - Flow Cytometry
Transfected with Human TWEAKR protein of HEK293 cells were stained with Enavatuzumab (anti-TWEAKR) (Ab183422) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, the EC50 for this effect is 46.94 nM.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0505694 | Certificate of Analysis | Mar 17, 2026 | Ab183422 |
| ZJ24F0505696 | Certificate of Analysis | Mar 17, 2026 | Ab183422 |
| ZJ24F0505700 | Certificate of Analysis | Mar 17, 2026 | Ab183422 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →
