Nonidet P 40 Substitute - Reagent grade , CAS No.9016-45-9

CAS: 9016-45-9 Cat. No.: N274285 EC Number: 500-024-6

GRADE & PURITY Reagent Grade

Storage

Store at 2-8°C

Shipped In

Wet ice,FedEx DG Service

Overview

This non-ionic detergent is suitable for solubilizing membrane proteins without altering biological activity.

Specifications

Specifications & Purity

Reagent grade

Storage

Store at 2-8°C

Shipped In

Wet ice, FedEx DG Service

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Reagent Grade

Names and Identifiers

• Isomeric SMILES: CCCCCCCCCC1=CC=C(C=C1)OCCOCCO
• WGK Germany: 2
• RTECS: AX0247000
• Alternate CAS: 26027-38-3；68412-54-4
• UN Number: 3082
• Packing Group: III

Chemical and Physical Properties

• Flash Point(°C): 113 °C
• Boil Point(°C): 290 °C

References

1. Li Mingyang, Song Xiaorong, Tu Haixia, Sun Jie, Deng Yuanyuan, Wang Bing, Cai Yuhan, Wang Yulian, Li Bin, Wang Yue, Zhang Xiangzheng, Wei Dong, Yang Xiaoyu, Guo Yueshuai, Li Xiang, Gu Jie, Ni Jie, Zhou Yifan, Gu Zhongze, Xie Zhuoying, Li Yan, Guo Xuejiang.  (2025)  A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids.  Nature Communications,  16  (1): (1-18).  [PMID:40819088] [10.1038/s41467-025-63075-0]

2. Meiyi Zou, Yuxia Liu, Lijuan Man, Yao Lan, Qian Wei, Wanjun Jin, Qinghui Chen, Yue Jia, Xinbo Yao, Yu Lu, Linjuan Huang, Zhongfu Wang, Chengjian Wang.  (2023)  Comprehensive Comparison of Bioactive N-Glycans among Seven Species of Livestock and Poultry Plasma Using a Relative Quantification Strategy.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:37972931] [10.1021/acs.jafc.3c03831]

3. Xu Ziye, Zhang Tianyu, Chen Hongyu, Zhu Yuyi, Lv Yuexiao, Zhang Shunji, Chen Jiaye, Chen Haide, Yang Lili, Jiang Weiqin, Ni Shengyu, Lu Fangru, Wang Zhaolun, Yang Hao, Dong Ling, Chen Feng, Zhang Hong, Chen Yu, Liu Jiong, Zhang Dandan, Fan Longjiang, Guo Guoji, Wang Yongcheng.  (2023)  High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq.  Nature Communications,  14  (1): (1-12).  [PMID:37173341] [10.1038/s41467-023-38409-5]

4. Chengjian Wang, Xi Gao, Guiping Gong, Lijuan Man, Qian Wei, Yao Lan, Meifang Yang, Jianli Han, Wanjun Jin, Ming Wei, Linjuan Huang, Zhongfu Wang.  (2022)  A versatile strategy for high-resolution separation of reducing glycan mixtures as hydrazones by two-dimensional high-performance liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36345072] [10.1016/j.chroma.2022.463599]

5. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang, Bin Di, Chi Hu.  (2022)  Teaching PCR for Simultaneous Sensing of Gene Transcription and Downstream Metabolites by Cucurbit[8]uril-Mediated Intervention of Polymerase Activity.  ANALYTICAL CHEMISTRY,      [PMID:35671188] [10.1021/acs.analchem.2c01103]

6. Peizhong Gao, Hang Yao, Shoujun Yuan, Yulan Wang, Wei Wang, Ibrahim Mohamed Ali, Zhen-Hu Hu.  (2021)  Degradation of Nonylphenol Ethoxylate-40 in High Saline Wastewater by Electrochemical Oxidation.  ENVIRONMENTAL ENGINEERING SCIENCE,  38  (2): (81-88).  [PMID:] [10.1089/ees.2020.0045]

7. Dan Wang, Jiangfei Lou, Jiugang Yuan, Jin Xu, Ruofei Zhu, Qiang Wang, Xuerong Fan.  (2020)  Laccase immobilization on core-shell magnetic metal-organic framework microspheres for alkylphenol ethoxylate compound removal.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2020.105000]

8. Haiyang Zhang, Yuanyuan Deng, Xinyi Liu, Jie Sun, Leyao Ma, Yajie Ding, Zhen Zhan, Hao Zhang, Yuchen Yang, Yanhong Gu, Anton B. Iliuk, Chenxi Yang, W. Andy Tao.  (2020)  Glass Fiber-Supported Hybrid Monolithic Spin Tip for Enrichment of Phosphopeptides from Urinary Extracellular Vesicles.  ANALYTICAL CHEMISTRY,      [PMID:33074658] [10.1021/acs.analchem.0c03557]

9. Xuexia Zhu, Zeshuang Wang, Yunfei Sun, Lei Gu, Lu Zhang, Jun Wang, Yuan Huang, Zhou Yang.  (2020)  Surfactants at environmentally relevant concentrations interfere the inducible defense of Scenedesmus obliquus and the implications for ecological risk assessment.  ENVIRONMENTAL POLLUTION,      [PMID:32066053] [10.1016/j.envpol.2020.114131]

10. Jian-Li HAN, Qing-Hui CHEN, Mei-Yi ZOU, Yu LU, Ming WEI, Cheng LI, Cheng-Jian WANG, Lin-Juan HUANG, Zhong-Fu WANG.  (2020)  Separation and Purification of Sialylglycopeptide from Egg Yolk Based on Cotton Hydrophilic Chromatography.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,      [PMID:] [10.1016/S1872-2040(19)61209-0]

11. Zilei Zhang, Danlei Liu, Qingping Wu, Yu Lu, Peng Tian, Zhongfu Wang, Dapeng Wang.  (2019)  Characterization of a Histo-Blood Group Antigen-like Substance in Romaine Lettuce That Contributes to Human Norovirus Attachment.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:31755264] [10.1021/acs.jafc.9b05887]

12. Bin Zhang, Yujie Jiang.  (2019)  QGO enhanced PET fibre for multi-applications.  Micro & Nano Letters,  14  (3): (224-229).  [PMID:] [10.1049/mnl.2018.5105]

13. Bin Zhang, Yujie Jiang.  (2018)  Durable antibacterial and hydrophobic polyester fibres and wearable textiles.  Micro & Nano Letters,  13  (7): (1011-1016).  [PMID:] [10.1049/mnl.2018.0197]

14. Naling Bai, Sheng Wang, Pengfei Sun, Rexiding Abuduaini, Xufen Zhu, Yuhua Zhao.  (2017)  Degradation of nonylphenol polyethoxylates by functionalized Fe3O4 nanoparticle-immobilized Sphingomonas sp. Y2.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:28988082] [10.1016/j.scitotenv.2017.09.290]

15. Lingmei Li, Chengjian Wang, Shan Qiang, Jixiang Zhao, Shuang Song, Wanjun Jin, Bo Wang, Ying Zhang, Linjuan Huang, Zhongfu Wang.  (2016)  Mass Spectrometric Analysis of N-Glycoforms of Soybean Allergenic Glycoproteins Separated by SDS-PAGE.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:27616296] [10.1021/acs.jafc.6b02773]

16. Chengjian Wang, Zhiyu Wu, Jiangbei Yuan, Bo Wang, Ping Zhang, Ying Zhang, Zhongfu Wang, Linjuan Huang.  (2013)  Simplified Quantitative Glycomics Using the Stable Isotope Label Girard’s Reagent P by Electrospray Ionization Mass Spectrometry.  JOURNAL OF PROTEOME RESEARCH,      [PMID:24274809] [10.1021/pr4010647]

17. Chengjian Wang, Jiangbei Yuan, Xiaohua Li, Zhongfu Wang, Linjuan Huang.  (2013)  Sulfonyl hydrazine-functionalized polymer as a specific capturer of reducing glycans from complex samples for high-throughput analysis by electrospray ionization mass spectrometry.  ANALYST,  138  (18): (5344-5356).  [PMID:23875183] [10.1039/C3AN00931A]

18. Dong Wei, Hao Zhang, Mingyang Li, Liuxi Chu.  (2025)  A novel strategy for biomarker discovery: Neutral loss-dependent acquisition of circulating extracellular vesicles for the detection of phosphopeptides.  Talanta Open,      [PMID:] [10.1016/j.talo.2025.100399]

19. Jiajun Li, Shaoqi Kong, Guochao Yan, Xuanlai Chen.  (2024)  Adsorption mechanism of alkylphenol ethoxylates surfactants (APEO) on anthracite surface: A combined experimental, DFT and molecular dynamics study.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2024.124030]

20. Sha-Sha Chen, Yong-Lei Yang, Hong-Yun Wang, Tian-Kui Guo, Riaz-M Azeem, Chun-Wei Shi, Gui-Lian Yang, Hai-Bin Huang, Yan-Long Jiang, Jian-Zhong Wang, Xin Cao, Nan Wang, Yan Zeng, Wen-Tao Yang, Chun-Feng Wang.  (2024)  CRISPR/Cas13a-based genome editing for establishing the detection method of H9N2 subtype avian influenza virus.  POULTRY SCIENCE,      [PMID:39096825] [10.1016/j.psj.2024.104068]

21. Feng Wu, Yaoyang Li, Linlin Zhang, Yuchen Zhou, Yili Xu, Youpeng Cai, Lingling Ding, Leilei Zhang, Yanfeng Wang, Hui Qian.  (2025)  Real-Time Isolation and Versatile Detection for Extracellular Vesicles Based on Ordered Porous Layer Interferometry.  ANALYTICAL CHEMISTRY,      [PMID:40045887] [10.1021/acs.analchem.4c07108]

22. Zhenyun Wang, Zhijiao Pan, Zhongquan Zhang, Qiaohong Zhang, Kefeng Luo, Chen Chen.  (2025)  Self-template synthesis of organic-inorganic hybrid mesoporous silica and its application in efficient removal of various organic polluted species from water.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.138981]

23. Tao Liu, Xu Zhang, Wei Zhang, Dejin Yang, Jipeng Li, Lin Liu.  (2026)  GSTA1 Depletes Glutathione and Exacerbates Oxidative Stress in α-Amanitin-Induced Hepatotoxicity.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:] [10.1016/j.cbi.2026.112058]