Recombinant Caspase-9 Antibody - Primary antibody, specific to CASP9, Rabbit IgG

Cat. No.: Ab093081

GRADE & PURITY Recombinant, Validated, ExactAb™, See COA

Application

IF/ICC, IHC, WB

Host species

Rabbit

Reactive species

Human

Isotype

Rabbit IgG

Conjugation

Unconjugated

Overview

Rabbit anti Human Caspase-9 Antibody, Recombinant, could be used for WB, IHC, IF/ICC and so on.

Specifications

Product Name

Recombinant Caspase-9 Antibody - Primary antibody, specific to CASP9, Rabbit IgG

Synonyms

MCH6 | Caspase-9 | CASP-9 | Apoptotic protease Mch-6 | Apoptotic protease-activating factor 3 | APAF-3 | ICE-like apoptotic protease 6 | ICE-LAP6 | CASP9 | APAF-3 antibody | APAF3 antibody | Apoptosis related cysteine peptidase antibody | Apoptotic protea

Specifications & Purity

Recombinant, ExactAb™, Validated, See COA

Biochemical and Physiological Mechanisms

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Host species

Rabbit

Specificity

CASP9

Immunogen

A synthetic peptide derived from human Caspase-9 (AA 299-318)

Positive Control

WB: Mouse brain, NIH/3T3 lysates. IHC: Human liver cancer tissue. IF/ICC: HeLa, Hep G2, 3T3 cells.

Conjugation

Unconjugated

Grade

ExactAb™, Recombinant, Validated

Isotype

Rabbit IgG

Light Chain Type

kappa

SDS-PAGE

150 kDa

Purification Method

Protein A purified

Concentration

See COA

Storage and Shipping

Shape

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Application

• Application: Dilution info
• IF/ICC:

  1/50-1/200 ;

• IHC:

  1/50-1/200;

• WB:

  1/500-1/2000 ;

Associated Targets(Human)

CASP9 Tchem Caspase-9 (0 Activities)

Discover Target: CASP9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CASP9 Tchem Caspase-9 (154 Activities)

Discover Target: CASP9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action