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LAT2 Mouse mAb - Primary antibody, specific to LAT2, Mouse IgG1

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LAT2 Mouse mAb - Primary antibody, specific to LAT2, Mouse IgG1

Name: LAT2 Mouse mAb - Primary antibody, specific to LAT2, Mouse IgG1
SKU: Ab112832
Availability: InStock

In stock

SKU

Ab112832

Grouped product items
Product Name	Qty
[Ab112832-10μl] LAT2 Mouse mAb (10μl) $99.90
[Ab112832-50μl] LAT2 Mouse mAb (50μl) $259.90
[Ab112832-100μl] LAT2 Mouse mAb (100μl) $419.90
[Ab112832-1ml] LAT2 Mouse mAb (1ml) $3,399.90

mAb (K52022_7A12); Mouse anti Human LAT2 Antibody; WB, IHC; Unconjugated

Mouse anti Human LAT2 Antibody, Monoclonal (K52022_7A12), could be used for WB, IHC and so on.
Application:
WB: 1/1000
IHC: 1/100-1/200
Protein Function
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Post-translational
Phosphorylated on tyrosines following cross-linking of BCR in B-cells, FCGR1 in myeloid cells, or FCER1 in mast cells; which induces the recruitment of GRB2.
May be polyubiquitinated.

More Information

More Information
Target	LAT2
Clone	K52022_7A12
Accession #	Q9GZY6
Synonyms	LAB antibody \| LAT2 antibody \| Linker for activation of B cells antibody \| Linker for activation of B-cells antibody \| Linker for activation of T cells family member 2 antibody \| Linker for activation of T cells transmembrane adaptor 2 antibody \| Linker f
Specifications & Purity	ExactAb™, Validated, Carrier Free, 1.0 mg/mL
Specificity	LAT2
Immunogen	Recombinant protein of human LAT2 (AA 121-220).
Positive Control	WB: U937, Raji and THP-1 cell lysates. IHC: Human tonsil tissue.
Isotype	Mouse IgG1
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Concentration	1.0 mg/mL
Product Description	Mouse anti Human LAT2 Antibody, Monoclonal (K52022_7A12), could be used for WB, IHC and so on. Application: WB: 1/1000 IHC: 1/100-1/200 Protein Function Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. Post-translational Phosphorylated on tyrosines following cross-linking of BCR in B-cells, FCGR1 in myeloid cells, or FCER1 in mast cells; which induces the recruitment of GRB2. May be polyubiquitinated.
Shape	Liquid
Storage	Store at -80°C,Avoid repeated freezing and thawing
Shipped In	Dry ice packs + Cold packs
Stability And Storage	Store at 2-8 ℃ (3 months). Store at -20 ℃ (12 months). Store at -80 ℃ (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.