Recombinant p21 Antibody - Primary antibody, specific to p21, Mouse IgG2a

Cat. No.: Ab119617
AVAILABLE TO ORDER
GRADE & PURITY Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. 2.4 mg/mL
Application
IHC
Host species
Mouse
Reactive species
Human
Isotype
Mouse IgG2a
Clone Number
MyM1-p21
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μl
Ab119617-10μl
5
$99.90
50μl
Ab119617-50μl
2
$259.90
100μl
Ab119617-100μl
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$419.90
1ml
Ab119617-1ml
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$1,999.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

ExactAb™, Validated, Recombinant, 2.4 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Avoid repeated freezing and thawing Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Mouse anti Human p21 Antibody, Recombinant (MyM1-p21), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Specifications

Product Name
Recombinant p21 Antibody - Primary antibody, specific to p21, Mouse IgG2a
Synonyms
CAP20 antibody | CDK-interacting protein 1 antibody | CDKI antibody | CDKN1 antibody | Cdkn1a antibody | CDN1A_HUMAN antibody | CIP1 antibody | Cyclin Dependent Kinase Inhibitor 1A antibody | Cyclin-dependent kinase inhibitor 1 antibody | Cyclin-dependent
Specifications & Purity
ExactAb™, Validated, Recombinant, 2.4 mg/mL
Host species
Mouse
Specificity
p21
Positive Control
IHC: Human tonsil and breast cancer tissues.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Isotype
Mouse IgG2a
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Concentration
2.4 mg/mL
Storage and Shipping
Shape
Liquid
Storage
Store at 2-8°C,Avoid repeated freezing and thawing
Shipped In
Wet ice
Stability And Storage
Store at 2-8°C long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Recombinant p21 Antibody (Ab119617) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Recombinant p21 Antibody (Ab119617) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Application
ApplicationDilution info
IHC

1/100 - 1/200

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
CDKN1A Tchem Cyclin-dependent kinase inhibitor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CDKN1A Tchem CDK-interacting protein 1 (92 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404783Certificate of AnalysisApr 23, 2024 Ab119617
ZJ24F0404782Certificate of AnalysisApr 23, 2024 Ab119617
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide →

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