Bevacizumab (anti-VEGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to VEGFA, >95%, Human IgG1, INHIBITOR of Vascular endothelial growth factor A inhibitor, INHIBITOR of Vascular endothelial growth factor A inhibitor

CAS: 216974-75-3 Cat. No.: B411998 Molecular Weight: 149 kDa(Average) EC Number: 692-134-7
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human, Mouse
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
B411998-100μg
4
$69.90
1mg
B411998-1mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.

$297.90

$349.90
Save $52.00 (14.86%)
5mg
B411998-5mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.

$1,331.90

$1,559.90
Save $228.00 (14.62%)
10mg
B411998-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.

$1,999.90

$2,339.90
Save $340.00 (14.53%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Bevacizumab (anti-VEGF) is a humanized anti-VEGF monoclonal antibody which binds to and neutralizes all human VEGF-A isoforms and bioactive proteolytic fragments.

Specifications

Product Name
Bevacizumab (anti-VEGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to VEGFA, >95%, Human IgG1, INHIBITOR of Vascular endothelial growth factor A inhibitor
Synonyms
Recombinant Bevacizumab Antibody | rhuMab VEGF | Avastin | Anti-Human VEGF | Humanized Antibody | Bevacizumab (Anti-Human VEGF, Humanized Antibody) | Bevacizumab | EC 2.7.10.1 antibody | FLT 1 antibody | FLT antibody | Flt-1 antibody | FLT1 antibody | Fms
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 re
Host species
Human
Specificity
VEGFA
Application
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
INHIBITOR
Mechanism of action
INHIBITOR of Vascular endothelial growth factor A inhibitor
Antibody Type
Primary antibody
Clonality
Recombinant
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
26.5 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 173.3 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Purity
>95%
Source
CHO supernatant
Concentration
See COA
CAS
216974-75-3
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Bevacizumab (anti-VEGF) (B411998) - ELISA
Immobilized Recombinant Human VEGF Protein (rp155965) at 1 μg/mL can bind Bevacizumab (anti-VEGF) (B411998) with the EC50 of 4.16 ng/mL.

Bevacizumab (anti-VEGF) (B411998) - SEC
The purity of Bevacizumab (anti-VEGF) (B411998) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
VEGFA Tclin Vascular endothelial growth factor A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202983Certificate of AnalysisDec 16, 2025 B411998
ZJ23F0800853Certificate of AnalysisAug 21, 2023 B411998
ZJ23F0800852Certificate of AnalysisAug 21, 2023 B411998
Documents & Articles
Citations of This Product
References
1. Wenjuan Huang, Liwen Wang, Ruhui Yang, Ronggui Hu, Qinxiang Zheng, Xingjie Zan.  (2022)  Combined delivery of small molecule and protein drugs as synergistic therapeutics for treating corneal neovascularization by a one-pot coassembly strategy.  Materials Today Bio,      [PMID:36281304] [10.1016/j.mtbio.2022.100456]
2. Yingchun Zeng, Jingxuan Yang, Ka Wang, Huan Xu, Yue Zheng, Songxin Guo, Jingwen Luo, Sha Liu, Xin Ming, Xue Ying.  (2025)  Multifunctional Polymeric Nanoparticles Codelivering Paclitaxel and Monoclonal Antibodies for Triple Combination Therapy of Colorectal Cancer.  BIOMACROMOLECULES,      [PMID:41246989] [10.1021/acs.biomac.5c01421]
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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