Integrin beta 3/CD61 Mouse mAb (APC) - Primary antibody, specific to Integrin beta 3

Cat. No.: Ab186829

GRADE & PURITY Validated, ExactAb™, 5 μL/test

Application

Flow Cytometry

Host species

Mouse

Reactive species

Human

Isotype

Mouse IgG1

Clone Number

HIP11

Conjugation

APC

Overview

Mouse anti Human Integrin beta 3/CD61 Antibody, Monoclonal (HIP11), could be used for Flow Cytometry.

Specifications

Product Name

Integrin beta 3/CD61 Mouse mAb (APC) - Primary antibody, specific to Integrin beta 3

Synonyms

BDPLT16 | BDPLT2 | BDPLT24 | GPIIIa | GT | GT2 | CD61 antigen | CD61 | GP3A | GP3Aplatelet glycoprotein IIIa | GPIIIaintegrin beta-3 | INGRB3 | Integrin beta 3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | ITG B3 | ITGB3 | Platelet membr

Specifications & Purity

ExactAb™, Validated, 5 μL/test

Biochemical and Physiological Mechanisms

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin,

Host species

Mouse

Specificity

Integrin beta 3

Immunogen

Normal peripheral blood platelets and platelets from IPT patients

Positive Control

Flow Cytometry: human peripheral blood platelets

Conjugation

APC

Excitation (nm)

Red Laser(633nm)

Emission(nm)

660nm

Ex/Em(nm)

Ex:650nm;Em:660nm

Grade

ExactAb™, Validated

Light Chain Type

kappa

Purification Method

Protein A purified

Concentration

5 μL/test

Storage and Shipping

Storage

Store at 2-8°C,Protected from light,Do not freeze

Shipped In

Wet ice,Do not freeze

Stability And Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Images

Flow Cytometry: Integrin beta 3/CD61 Mouse mAb (APC) (Ab186829)

Integrin beta 3/CD61 Mouse mAb (APC) (Ab186829) - Flow Cytometry
Flow cytometry analysis of Integrin beta 3/CD61 expression by human peripheral blood platelets (red) compared to an isotype control (blue). Cells were stained with  Integrin beta 3/CD61 Mouse mAb (APC) (Ab186829) at 0.1μg/test for 1 hour at 4°C. Blue - Mouse IgG (APC) (Ab180309). Black - Unlabelled control, cells without incubation with primary antibody.

Application

• Application: Dilution info
• Flow Cytometry:

  5μl/test

  For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.

Associated Targets(Human)

ITGB3 Tclin Integrin beta-3 (0 Activities)

Discover Target: ITGB3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)