CXCR4/CD184 Mouse mAb (APC) - Primary antibody, specific to CXCR4/CD184

Cat. No.: Ab212891

GRADE & PURITY Validated, ExactAb™, 2 μL/test

Application

Flow Cytometry

Host species

Mouse

Reactive species

Human

Isotype

Mouse IgG2a

Clone Number

12G5

Conjugation

APC

Overview

Mouse anti Human CXCR4/CD184 Antibody, Monoclonal (12G5), could be used for Flow Cytometry.

Specifications

Product Name

CXCR4/CD184 Mouse mAb (APC) - Primary antibody, specific to CXCR4/CD184

Synonyms

WHIM | WHIMS1 | D2S201E | CD184 | chemokine (C-X-C motif) receptor 4 | chemokine (C-X-C motif), receptor 4 (fusin) | C-X-C chemokine receptor type 4 | CXCR4 | CXC-R4 | CXCR-4 | D2S201ESDF-1 receptor | FB22 | Fusin | HM89 | HM89NPYRL | HSY3RR | LAP3 | LAP-

Specifications & Purity

ExactAb™, Validated, 2 μL/test

Biochemical and Physiological Mechanisms

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and

Host species

Mouse

Specificity

CXCR4/CD184

Positive Control

Flow Cytometry: Jurkat

Conjugation

APC

Excitation (nm)

Red Laser(633nm)

Emission(nm)

660nm

Ex/Em(nm)

Ex:650nm;Em:660nm

Grade

ExactAb™, Validated

Light Chain Type

kappa

Purification Method

Protein A/G purified

Concentration

2 μL/test

Storage and Shipping

Storage

Store at 2-8°C,Protected from light,Do not freeze

Shipped In

Wet ice,Do not freeze

Stability And Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Images

Flow Cytometry: CXCR4/CD184 Mouse mAb (APC) (Ab212891)

CXCR4/CD184 Mouse mAb (APC) (Ab212891) - Flow Cytometry
Flow cytometry analysis of CXCR4/CD184 expression by Jurkat cells (red) compared to an isotype control (blue). Cells were stained with CXCR4/CD184 Mouse mAb (APC) (Ab212891) at 2μL/test for 1 hour at 4°C. Blue - Mouse IgG (APC) (Ab180309). Black - Unlabelled control, cells without incubation with primary antibody.

Application

• Application: Dilution info
• Flow Cytometry:

  2 μL/test; For flow cytometric staining, the suggested use of this reagent is 2 µL per million cells in 100 µL staining volume or 2 µL per 100 µL of whole blood.

Associated Targets(Human)

CXCR4 Tclin C-X-C chemokine receptor type 4 (0 Activities)

Discover Target: CXCR4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)