Product Name
Cetuximab (anti-EGFR) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB1/EGFR/HER1, >95%, Human IgG1, Antibody of epidermal growth factor receptor
Synonyms
C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference Antibody (cetuximab) | Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibo
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin,
Specificity
ERBB1/EGFR/HER1
Application
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Mechanism of action
Antibody of epidermal growth factor receptor
Antibody Type
Primary antibody
SDS-PAGE
28.4 kDa (Light Chain) & 53.4 kDa (Heavy Chain), under reducing conditions; 184.2 kDa, under non-reducing conditions.
Purification Method
Protein A purified