Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ACS, ≥99.5%(T) ACS,Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1982 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Citric Acid is an acidic compound from citrus fruits; as a starting point in the Krebs cycle, citrate is a key intermediate in metabolism. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Often used to prepare citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot. May be used to adjust pH and as a sequestering agent for the removal of trace metals.
Used in the preparation of citrate buffer for antigen and epitope unmasking in IHC.
| Pubchem Sid | 508813593 |
|---|---|
| Canonical Smiles | C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| IUPAC Name | 2-hydroxypropane-1,2,3-tricarboxylic acid |
| InChIKey | KRKNYBCHXYNGOX-UHFFFAOYSA-N |
| INCHI | 1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12) |
| Isomeric SMILES | C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| WGK Germany | 1 |
| RTECS | GE7350000 |
| Molecular Weight | 192.12 |
| Beilstein | 782061 |
| Reaxy-Rn | 782061 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=782061&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Tricarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Tricarboxylic acids and derivatives |
| Alternative Parents | Alpha hydroxy acids and derivatives Tertiary alcohols Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Tricarboxylic acid or derivatives - Hydroxy acid - Alpha-hydroxy acid - Tertiary alcohol - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups. |
| External Descriptors | tricarboxylic acid |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 09, 2026 | C108873 | |
| Certificate of Analysis | May 09, 2026 | C108873 | |
| Certificate of Analysis | Apr 27, 2026 | C108873 | |
| Certificate of Analysis | Jan 07, 2026 | C108873 | |
| Certificate of Analysis | Nov 06, 2025 | C108873 | |
| Certificate of Analysis | Aug 01, 2025 | C108873 | |
| Certificate of Analysis | Mar 18, 2025 | C108873 | |
| Certificate of Analysis | Feb 17, 2025 | C108873 | |
| Certificate of Analysis | Aug 23, 2024 | C108873 | |
| Certificate of Analysis | May 07, 2024 | C108873 | |
| Certificate of Analysis | Mar 01, 2024 | C108873 | |
| Certificate of Analysis | Jun 29, 2023 | C108873 | |
| Certificate of Analysis | Feb 28, 2022 | C108873 | |
| Certificate of Analysis | Feb 28, 2022 | C108873 | |
| Certificate of Analysis | Feb 28, 2022 | C108873 |
| Solubility | Soluble in alcohol, water (750 mg/ml at 20 °C), and methanol. Insoluble in chloroform, and benzenz. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Melt Point(°C) | 153-159°C |
| Molecular Weight | 192.120 g/mol |
| XLogP3 | -1.700 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 192.027 Da |
| Monoisotopic Mass | 192.027 Da |
| Topological Polar Surface Area | 132.000 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 227.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide → View ACS grade guide →