4',6-Diamidino-2-phenylindole Dihydrochloride - ≥97% , CAS No.28718-90-3

CAS: 28718-90-3 Cat. No.: D489987 Molecular Weight: 350.25 Beilstein Registry Number: 4894417 EC Number: 249-186-7 PubChem CID: 160166

GRADE & PURITY ≥97%

Synonyms

AKOS015902963 | CCRIS 8836 | 4',6-Diamidino-2-phenylindole dihydrochloride, suitable for fluorescence, BioReagent, >=95.0% (HPLC) | UNII-76BFW26YJO | 2-(4-CARBAMIMIDOYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE 2HCL | 4',6-diamidino-2-phenylindole hydrochloride

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

4',6-Diamidino-2-phenylindole Dihydrochloride  is a fluorescent dye used for DNA staining. It strongly interacts with dAT (deoxyadenosine thymine) rich regions in DNA.

Specifications

Synonyms

AKOS015902963 | CCRIS 8836 | 4', 6-Diamidino-2-phenylindole dihydrochloride, suitable for fluorescence, BioReagent, >=95.0% (HPLC) | UNII-76BFW26YJO | 2-(4-CARBAMIMIDOYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE 2HCL | 4', 6-diamidino-2-phenylindole hydrochloride

Specifications & Purity

≥97%

Biochemical and Physiological Mechanisms

Fluorescent DNA stain. Binds to AT-rich regions of DNA. Cell permeable at high concentrations.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 504757478
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504757478
• Canonical Smiles: C1=CC(=CC=C1C2=CC3=C(N2)C=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
• IUPAC Name: 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide;dihydrochloride
• InChIKey: FPNZBYLXNYPRLR-UHFFFAOYSA-N
• INCHI: 1S/C16H15N5.2ClH/c17-15(18)10-3-1-9(2-4-10)13-7-11-5-6-12(16(19)20)8-14(11)21-13;;/h1-8,21H,(H3,17,18)(H3,19,20);2*1H
• Isomeric SMILES: C1=CC(=CC=C1C2=CC3=C(N2)C=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
• WGK Germany: 3
• PubChem CID: 160166
• Molecular Weight: 350.25
• Beilstein: 4894417
• Reaxy-Rn: 4894417

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Indoles and derivatives
      • Subclass Indoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Indoles and derivatives
• Subclass: Indoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 2-phenylindoles
• Alternative Parents: Phenylpyrroles Benzene and substituted derivatives Heteroaromatic compounds Carboximidamides Carboxamidines Azacyclic compounds Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 2-phenylindole - 2-phenylpyrrole - Monocyclic benzene moiety - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Amidine - Carboxylic acid amidine - Azacycle - Carboximidamide - Organopnictogen compound - Organonitrogen compound - Hydrocarbon derivative - Organic nitrogen compound - Hydrochloride - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 2-phenylindoles. These are indoles substituted at the 2-position with a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 35.02, Max Conc. mM: 100; Solvent:water, Max Conc. mg/mL: 3.5, Max Conc. mM: 10 with gentle warming
• Sensitivity: Light & Heat Sensitive；Moisture sensitive
• Molecular Weight: 350.200 g/mol
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 349.086 Da
• Monoisotopic Mass: 349.086 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 413.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Ji Hongfei, Zhao Yanyan, Ma Xiaojun, Wu Lina, Guo Feng, Huang Fengjuan, Song Yi, Wang Jiao, Qin Guijun.  (2023)  Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.  INFLAMMATION,      [PMID:38055118] [10.1007/s10753-023-01940-0]

2. Junya Lu, Luming Song, Shuaipeng Feng, Kaili Wang, Yuling Mao, Yikun Gao, Qinfu Zhao, Siling Wang.  (2023)  Nanozyme-mediated biocatalysis as a mitochondrial oxidative stress amplifier for tumor nanocatalytic immunotherapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.148270]

3. Xiaoqian Guo, Guangwei Qiao, Jingjiao Wang, Changyi Yang, Min Zhao, Qian Zhang, Yingbiao Wan.  (2023)  TIFA contributes to periodontitis in diabetic mice via activating the NF‑κB signaling pathway.  Molecular Medicine Reports,  29  (2): (1-11).  [PMID:38099344] [10.3892/mmr.2023.13146]

4. Lei Ming, Lin Hui, Shi Deyao, Hong Pan, Song Hui, Herman Bomansaan, Liao Zhiwei, Yang Cao.  (2023)  Molecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration.  CELLULAR & MOLECULAR BIOLOGY LETTERS,  28  (1): (1-24).  [PMID:38093179] [10.1186/s11658-023-00517-x]

5. Liu Yingli, Zhu Li, Ming Yue, Wu Zhuhua, Zhang Lili, Chen Qi, Qi Yong.  (2023)  A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylation modification.  Journal of Translational Medicine,  21  (1): (1-22).  [PMID:37978515] [10.1186/s12967-023-04712-4]

6. Jianhui Wu, Wanbo Xue, Chunhua Wang, Haibin Gu, Jiajing Zhou, Wei Lin.  (2023)  Bioactive Porous Protein Scaffolds Enabled by High Internal Phase Emulsion Templates.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.3c02475]

7. Jin Xin, Xu Hainan, Hu Qing, Yin Yitong, Qin Meiying, Xia Zhijun.  (2023)  Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse.  HISTOCHEMISTRY AND CELL BIOLOGY,      [PMID:37874337] [10.1007/s00418-023-02240-2]

8. Zhang Meixia, Wang Zhonghou, Yang Guang, Han Linfu, Wang Xiaofeng.  (2023)  NFE2L1 restrains ferroptosis by transcriptionally regulating HJURP and participates in the progress of oral squamous cell carcinoma.  JOURNAL OF BIOENERGETICS AND BIOMEMBRANES,      [PMID:37848756] [10.1007/s10863-023-09987-2]

9. Jun Li, Changjun Yu, Kangmin Yu, Zhiyong Chen, Dan Xing, Binshan Zha, Wentao Xie, Huan Ouyang.  (2023)  SPINT2 is involved in the proliferation, migration and phenotypic switching of aortic smooth muscle cells: Implications for the pathogenesis of thoracic aortic dissection.  Experimental and Therapeutic Medicine,  26  (6): (1-12).  [PMID:37928510] [10.3892/etm.2023.12245]

10. Ling Tang, Liyuan Wang, Feng Jin, Yuehan Hao, Tianming Zhao, Wenxu Zheng, Zhiyi He.  (2023)  Inflammatory regulation by restraining M2 microglial polarization: Neurodestructive effects of Kallikrein-related peptidase 8 activation in intracerebral hemorrhage.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:37678029] [10.1016/j.intimp.2023.110855]

11. Naiquan Liu, Dongyang Li, Dajun Liu, Ying Liu, Jing Lei.  (2023)  FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells.  Journal of Translational Internal Medicine,  11  (3): (294-308).  [PMID:37662889] [10.2478/jtim-2023-0105]

12. Yu Zhu, Longmei Wang, Rui Liu, Xiurong Ding, Song Yin, Yuankun Chen, Chuanlong Zhu, Zheng Wang, Wenting Li.  (2023)  Inhibition of PRMT1 alleviates sepsis-induced acute kidney injury in mice by blocking the TGF-β1 and IL-6 trans-signaling pathways.  FEBS Open Bio,      [PMID:37525933] [10.1002/2211-5463.13684]

13. Ziyuan Tong, Yuan Shen, Quan Yuan, Honghao Yu.  (2023)  HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH,      [PMID:37527738] [10.1016/j.bbamcr.2023.119553]

14. Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun.  (2023)  Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis.  Molecular Medicine Reports,  28  (3): (1-14).  [PMID:37449526] [10.3892/mmr.2023.13050]

15. Yingying Chen, Zhong He, Bo Zhao, Rui Zheng.  (2023)  Downregulation of a potential therapeutic target NPAS2, regulated by p53, alleviates pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via suppressing HES1.  CELLULAR SIGNALLING,      [PMID:37406788] [10.1016/j.cellsig.2023.110795]

16. Han Sijia, Jin Xueying, Hu Tianyu, Chi Feng.  (2023)  ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.  CARCINOGENESIS,      [PMID:37326327] [10.1093/carcin/bgad042]

17. Shixiong Lei, Xilin Du, Kai Tan, Xiaojun He, Yejing Zhu, Shoujie Zhao, Zhenyu Yang, Gang Dou.  (2023)  CRP‑1 promotes the malignant behavior of hepatocellular carcinoma cells via activating epithelial‑mesenchymal transition and Wnt/β‑catenin signaling.  Experimental and Therapeutic Medicine,  26  (1): (1-10).  [PMID:37273753] [10.3892/etm.2023.12013]

18. Jiajia Zhai, Zeping Li, Huifeng Zhang, Zuowei Lu, Yi Zhang, Mo Li, Jian Kang, Zelong Yang, Louyan Ma, Li Ma, Zhengquan Ma, Xiaorui Ma, Fanghong Zhao, Xiaoqing Ma, Yuan Gao, Yuanyuan Zhang, Xiaomiao Li.  (2023)  Coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome.  Open Life Sciences,  18  (1):   [PMID:37197172] [10.1515/biol-2022-0568]

19. Ni-Na Song, Ying Zhao, Chuang Sun, Jun Zhang, Guang-Jun Lin, Xiao-Wei Yin, Chun-Ye Ma.  (2023)  DUSP10 alleviates ischemic stroke-induced neuronal damage by restricting p38/JNK pathway.  BEHAVIOURAL BRAIN RESEARCH,      [PMID:37164190] [10.1016/j.bbr.2023.114478]

20. Xi Fu, Peng Fu, Tiangui Yang, Tiesheng Niu.  (2023)  Homeobox A9 is a novel mediator of vascular smooth muscle cell phenotypic switching and proliferation by regulating methyl-CpG binding protein 2.  CELLULAR SIGNALLING,      [PMID:37127144] [10.1016/j.cellsig.2023.110695]

21. Liangjie Lu, Huihan Wang, Minjie Yang, Lijun Wang, Kaifeng Gan.  (2023)  Three-dimensional-printed MPBI@β-TCP scaffold promotes bone regeneration and impedes osteosarcoma under near-infrared laser irradiation.  FASEB JOURNAL,  37  (5): (e22924).  [PMID:37071462] [10.1096/fj.202201991R]

22. Tianjiao Ma, Lei Yang, Binmei Zhang, Xin Lv, Feifei Gong, Wei Yang.  (2023)  Hydrogen inhalation enhances autophagy via the AMPK/mTOR pathway, thereby attenuating doxorubicin-induced cardiac injury.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:37080067] [10.1016/j.intimp.2023.110071]

23. Yanli Song, Dongjie He, Shaoqi Shi, Tianwei Cui, Hui Zhang, Xianmin Zhao, Tingting Ni, Huidongzi Xiao, Aiwu Wei.  (2023)  Hyperoside exerts protective effects against anticardiolipin antibody-induced recurrent pregnancy loss in vivo and in vitro.  HUMAN & EXPERIMENTAL TOXICOLOGY,      [PMID:37042322] [10.1177/09603271231163476]

24. Jing Cong, Mubai Li, Yu Wang, Hongli Ma, Xinming Yang, Jingshu Gao, Long Wang, Xiaoke Wu.  (2023)  Protective effects of electroacupuncture on polycystic ovary syndrome in rats: Down-regulating Alas2 to inhibit apoptosis, oxidative stress, and mitochondrial dysfunction in ovarian granulosa cells.  TISSUE & CELL,      [PMID:37075681] [10.1016/j.tice.2023.102090]

25. Liu Xu-Ying, Li Qiu-Shi, Yang Wen-Hai, Qiu Yue, Zhang Fei-Fei, Mei Xiu-Hui, Yuan Qi-Wen, Sui Ru-Bo.  (2023)  Inhibition of perilipin 2 attenuates cerebral ischemia/reperfusion injury by blocking NLRP3 inflammasome activation both in vivo and in vitro.  IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL,  59  (3): (204-213).  [PMID:37010675] [10.1007/s11626-023-00759-1]

26. Li Liang, Weiliang Sun, Xiaoxuan Wei, Li Wang, Huaqiang Ruan, Junchuan Zhang, Suyan Li, Bi Zhao, Mengshi Li, Zhengwen Cai, Jie'an Huang.  (2023)  Oxymatrine suppresses colorectal cancer progression by inhibiting NLRP3 inflammasome activation through mitophagy induction in vitro and in vivo.  PHYTOTHERAPY RESEARCH,      [PMID:36974424] [10.1002/ptr.7808]

27. Yijuan Wu, Zhiyu Wang, Shengmian Li, Xianliang Chen, Shengyun Zhou.  (2023)  SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.  Experimental and Therapeutic Medicine,  25  (5): (1-16).  [PMID:37090067] [10.3892/etm.2023.11894]

28. Jie Meng, Peng Zhang, Qingjie Liu, Pan Ran, Shuang Xie, Junwu Wei, Xiaohong Li.  (2023)  Pyroelectric Janus nanomotors for synergistic electrodynamic-photothermal-antibiotic therapies of bacterial infections.  Acta Biomaterialia,      [PMID:36931421] [10.1016/j.actbio.2023.03.012]

29. Wu Zhuhua, Zhu Li, Nie Xinran, Liu Yingli, Zhang Xiaoju, Qi Yong.  (2023)  Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction.  RESPIRATORY RESEARCH,  24  (1): (1-18).  [PMID:36922854] [10.1186/s12931-023-02382-w]

30. Jing Qiu, Jun Guo, Liang Liu, Xin Liu, Xianhui Sun, Huisheng Chen.  (2023)  Vav1 promotes inflammation and neuronal apoptosis in cerebral ischemia/reperfusion injury by upregulating microglial and NLRP3 inflammasome activation.  Neural Regeneration Research,      [PMID:37282474] [10.4103/1673-5374.371368]

31. Hai-Tao Yang, Guan Wang, Peng-Cheng Zhu, Zhao-Yang Xiao.  (2023)  Silencing EIF3A ameliorates pulmonary arterial hypertension through HDAC1 and PTEN/PI3K/AKT pathway in vitro and in vivo.  EXPERIMENTAL CELL RESEARCH,      [PMID:36921705] [10.1016/j.yexcr.2023.113555]

32. Cai Jimin, Yang Yang, Han Jiahui, Gao Yu, Li Xin, Ge Xin.  (2023)  KDM4A, involved in the inflammatory and oxidative stress caused by traumatic brain injury-hemorrhagic shock, partly through the regulation of the microglia M1 polarization.  BMC NEUROSCIENCE,  24  (1): (1-12).  [PMID:36869312] [10.1186/s12868-023-00784-6]

33. Ce XU, Jiahui HAN, Di JIA, Jimin CAI, Jianming YUAN, Xin GE.  (2023)  SIRT3 confers protection against acute pulmonary embolism by anti-inflammation, anti-oxidative stress, anti-apoptosis: participation of AMPK/mTOR pathway.  EXPERIMENTAL ANIMALS,      [PMID:36858596] [10.1538/expanim.22-0175]

34. Haixu Wang, Yan Li, Chuang Liu, Tianxiang Lu, Qian Zhai, Hongna Wang, Jianfang Zhang.  (2023)  Inhibition of VDAC1 prevents oxidative stress and apoptosis induced by bisphenol A in spermatogonia via AMPK/mTOR signaling pathway.  JOURNAL OF TOXICOLOGICAL SCIENCES,      [PMID:36858637] [10.2131/jts.48.109]

35. Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi.  (2023)  LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway.  ONCOLOGY REPORTS,  49  (3): (1-14).  [PMID:36799186] [10.3892/or.2023.8497]

36. Li Jiang, Chunrui Wang, Rui Zhao, Jing Cao, Yaohui Liu, Linli Tian, Ming Liu.  (2023)  Silencing SOX11 Alleviates Allergic Rhinitis by Inhibiting Epithelial-Derived Cytokines.  Balkan Medical Journal,      [PMID:36571426] [10.4274/balkanmedj.galenos.2022.2022-9-31]

37. Wu Zhuhua, Zhu Li, Nie Xinran, Wei Li, Qi Yong.  (2023)  USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner.  EXPERIMENTAL AND MOLECULAR MEDICINE,  55  (1): (183-195).  [PMID:36635430] [10.1038/s12276-022-00920-y]

38. Lu Yang, Zhao Wang, HaiJiang Gong, Shili Gai, RuiFang Shen.  (2022)  Tirapazamine-loaded UiO-66/Cu for ultrasound-mediated promotion of chemodynamic therapy cascade hypoxia-activated anticancer therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:36542978] [10.1016/j.jcis.2022.12.015]

39. Ying Zhang, Changjun Yin, Chao Wei, Shuai Xia, Zhu Qiao, Xue-Wen Zhang, Bin Yu, Jun Zhou, Rong Wang.  (2022)  Exosomal miR-625-3p secreted by cancer-associated fibroblasts in colorectal cancer promotes EMT and chemotherapeutic resistance by blocking the CELF2/WWOX pathway.  PHARMACOLOGICAL RESEARCH,      [PMID:36336217] [10.1016/j.phrs.2022.106534]

40. Shurong Duan, Fei Wang, Jingwei Cao, Chunyan Wang.  (2022)  Exosomes Derived from MicroRNA-146a-5p-Enriched Bone Marrow Mesenchymal Stem Cells Alleviate Intracerebral Hemorrhage by Inhibiting Neuronal Apoptosis and Microglial M1 Polarization.  Drug Design Development and Therapy,      [PMID:32821084] [10.2147/DDDT.S255828]

41. Xu Ai-Hua, Yang Yang, Shao Yang, Jiang Man-Yu, Sun Yong-Xin.  (2022)  Poly(ADP-ribose) polymerase family member 14 promotes functional recovery after spinal cord injury through regulating microglia M1/M2 polarization via STAT1/6 pathway.  Neural Regeneration Research,  18  (8): (1809).  [PMID:36751810] [10.4103/1673-5374.357909]

42. Jing Cong, Yuehui Zhang, Xinming Yang, Yu Wang, Hui He, Mengying Wang.  (2022)  Anti-polycystic ovary syndrome effect of electroacupuncture: IMD inhibits ER stress-mediated apoptosis and autophagy in granulosa cells.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,      [PMID:36244114] [10.1016/j.bbrc.2022.10.030]

43. Min Mu, Xiaoyan Liang, Na Zhao, Di Chuan, Bo Chen, Shasha Zhao, Guoqing Wang, Rangrang Fan, Bingwen Zou, Bo Han, Gang Guo.  (2022)  Boosting ferroptosis and microtubule inhibition for antitumor therapy via a carrier-free supermolecule nanoreactor.  Journal of Pharmaceutical Analysis,      [PMID:36816538] [10.1016/j.jpha.2022.09.003]

44. Lin Yan, Wang Dongxu, Zhao Hong, Li Dongyue, Li Xinning, Lin Lianjie.  (2022)  Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation.  CELLULAR & MOLECULAR BIOLOGY LETTERS,  27  (1): (1-15).  [PMID:36064319] [10.1186/s11658-022-00374-0]

45. Haihua Zhang, Wuying Lang, Sufen Li, Chao Xu, Xiumin Wang, Yunyu Li, Zhiqiang Zhang, Tonglei Wu, Minshan Feng.  (2022)  Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway.  IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY,      [PMID:35980837] [10.1080/08923973.2022.2112218]

46. Kai KANG, Lukuan CUI, Qian ZHANG, Shijun GAO.  (2022)  Lrrc32 accelerates tenogenic differentiation of tendon-derived stem cells and promotes Achilles tendon repair in rats.  EXPERIMENTAL ANIMALS,      [PMID:35934780] [10.1538/expanim.22-0009]

47. Yang Fan, Li Lin, Mu Zhenzhen, Liu Pengyue, Wang Ying, Zhang Yue, Han Xiuping.  (2022)  Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1.  CANCER GENE THERAPY,  29  (12): (1939-1950).  [PMID:35902727] [10.1038/s41417-022-00508-8]

48. Song Guiyu, Jin Feng.  (2022)  RhoGDI1 interacts with PHLDA2, suppresses the proliferation, migration, and invasion of trophoblast cells, and participates in the pathogenesis of preeclampsia.  Human Cell,  35  (5): (1440-1452).  [PMID:35841528] [10.1007/s13577-022-00746-w]

49. Chenlan Xu, Shuting Chen, Cuiping Chen, Yangcan Ming, Jiahao Du, Jinyi Mu, Fang Luo, Da Huang, Na Wang, Zhenyu Lin, Zuquan Weng.  (2022)  Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:35661797] [10.1016/j.ijpharm.2022.121884]

50. Haihua Zhang, Jing Wang, Wuying Lang, Hongli Liu, Zhiqiang Zhang, Tonglei Wu, Hongqiang Li, Liya Bai, Qiumei Shi.  (2022)  Albiflorin ameliorates inflammation and oxidative stress by regulating the NF-κB/NLRP3 pathway in Methotrexate-induced enteritis.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:35561481] [10.1016/j.intimp.2022.108824]

51. Jieru Han, Wenhao Li, Guangyu Shi, Yunlei Huang, Xutao Sun, Na Sun, Deyou Jiang.  (2022)  Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1α.  MEDIATORS OF INFLAMMATION,      [PMID:35431653] [10.1155/2022/9129984]

52. Wang Jingyu, Wang Yaqing, Liu Yi, Cai Xintian, Huang Xin, Fu Wenjing, Wang Lei, Qiu Lihua, Li Junying, Sun Li.  (2022)  Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model.  Cell Death Discovery,  8  (1): (1-10).  [PMID:35318301] [10.1038/s41420-022-00931-8]

53. Suwen Liu, Fanna Meng, Dong Zhang, Donglin Shi, Junyi Zhou, Shuo Guo, Xuedong Chang.  (2022)  Lonicera caerulea Berry Polyphenols Extract Alleviates Exercise Fatigue in Mice by Reducing Oxidative Stress, Inflammation, Skeletal Muscle Cell Apoptosis, and by Increasing Cell Proliferation.  Frontiers in Nutrition,      [PMID:35356725] [10.3389/fnut.2022.853225]

54. Jie Zhao, Yue Wu, Shanshan Liang, Xiangyu Piao.  (2022)  Activation of SSAT1/ALOX15 Axis Aggravates Cerebral Ischemia/Reperfusion Injury via Triggering Neuronal Ferroptosis.  NEUROSCIENCE,      [PMID:35090880] [10.1016/j.neuroscience.2022.01.017]

55. Yu Tao, Fu Hui, Sun Jing-Jing, Ding Dan-Rui, Wang Hua.  (2021)  miR-106b-5p upregulation is associated with microglial activation and inflammation in the mouse hippocampus following status epilepticus.  EXPERIMENTAL BRAIN RESEARCH,  239  (11): (3315-3325).  [PMID:34476536] [10.1007/s00221-021-06208-3]

56. Wenjun Zheng, Bing Liu, Enyi Shi.  (2021)  Perillaldehyde Alleviates Spinal Cord Ischemia-Reperfusion Injury Via Activating the Nrf2 Pathway.  JOURNAL OF SURGICAL RESEARCH,      [PMID:34399353] [10.1016/j.jss.2021.06.055]

57. Limei Yan, Zeping He, Wei Li, Ning Liu, Song Gao.  (2021)  P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.  CELL CYCLE,      [PMID:34382920] [10.1080/15384101.2021.1963910]

58. Min Wu, Mengmeng Jin, Xiaohui Cao, Kun Qian, Lei Zhao.  (2021)  RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression.  DRUG DEVELOPMENT RESEARCH,  83  (2): (328-338).  [PMID:34319598] [10.1002/ddr.21861]

59. Qiang Zheng, Hang Zhao, Dong Jia, Xu Han, Zhenning Liu, Min Zhao.  (2021)  Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll-Like Receptor 2/4 Signaling.  MEDIATORS OF INFLAMMATION,      [PMID:34335089] [10.1155/2021/5571272]

60. Xinyue Zhou, Zhenyu Chen, Lipeng Pei, Jingli Sun.  (2021)  MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway.  Bioengineered,      [PMID:34082653] [10.1080/21655979.2021.1933679]

61. Ying Xu, Yunxia Dong, Cong Wang, Qian Jiang, Haichao Chu, Yue Tian.  (2021)  Lovastatin attenuates sevoflurane-induced cognitive disorder in aged rats via reducing Aβ accumulation.  NEUROCHEMISTRY INTERNATIONAL,      [PMID:34048842] [10.1016/j.neuint.2021.105078]

62. Shuhua Chang, Dawei Qin, Lizhen Wang, Mengli Zhang, Rongjun Yan, Cuiyun Zhao.  (2021)  Preparation of novel cinnamaldehyde derivative–BSA nanoparticles with high stability, good cell penetrating ability, and promising anticancer activity.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2021.126765]

63. Mengyuan Fang, Wencui Wan, Qiuming Li, Weiwei Wan, Yang Long, Hongzhuo Liu, Xin Yang.  (2021)  Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.  LIFE SCIENCES,      [PMID:33965378] [10.1016/j.lfs.2021.119567]

64. Abdul Razaq HIRMAN, Lili DU, Shaohang CHENG, Heng ZHENG, Linna DUO, Qianyu ZHAI, Jing XU.  (2021)  MiR-133a-3p inhibits scar formation in scalded mice and suppresses the proliferation and migration of scar derived-fibroblasts by targeting CTGF.  EXPERIMENTAL ANIMALS,      [PMID:33658464] [10.1538/expanim.20-0159]

65. Tianren Xu, Xiaojiao Zhu, Li Yang, Yingcui Bu, Yuyang Zhang, Jie Zhang, Lianke Wang, Zhipeng Yu, Hongping Zhou.  (2020)  Defective transition metal hydroxide-based nanoagents with hypoxia relief for photothermal-enhanced photodynamic therapy.  Journal of Materials Chemistry B,  9  (4): (1018-1029).  [PMID:33432955] [10.1039/D0TB02486D]

66. Zhaohui Shi, Min Xu, Xiaodong Chen, Jian Wang, Tianfeng Zhao, Dingjun Zha.  (2020)  The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells.  EXPERIMENTAL AND MOLECULAR PATHOLOGY,      [PMID:33285209] [10.1016/j.yexmp.2020.104591]

67. Chen Jun, Li Lihua, Zhou Yun, Zhang Jiahua, Chen Lei.  (2020)  Gambogic acid ameliorates high glucose– and palmitic acid–induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.  CELL STRESS & CHAPERONES,  26  (2): (367-375).  [PMID:33245515] [10.1007/s12192-020-01182-1]

68. Yongkui Wang, Jian Chen, Jing Chen, Chao Dong, Xu Yan, Zhongpei Zhu, Pan Lu, Zongmian Song, Hongjian Liu, Songfeng Chen.  (2020)  Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:33171191] [10.1016/j.taap.2020.115333]

69. Xiaolong Sun, Xu Wang, Zhenyu Zhao, Jing Chen, Cheng Li, Gang Zhao.  (2020)  Paeoniflorin accelerates foot wound healing in diabetic rats though activating the Nrf2 pathway.  ACTA HISTOCHEMICA,      [PMID:33166863] [10.1016/j.acthis.2020.151649]

70. Han Jieru, Shi Guangyu, Li Wenhao, Xie Ying, Li Fuzhen, Jiang Deyou.  (2020)  Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study.  Journal of Natural Medicines,  75  (1): (37-47).  [PMID:32761488] [10.1007/s11418-020-01440-7]

71. Yanjing Dong, Zikang Chen, Meirong Hou, Li Qi, Chenggong Yan, Xiaodan Lu, Ruiyuan Liu, Yikai Xu.  (2019)  Mitochondria-targeted aggregation-induced emission active near infrared fluorescent probe for real-time imaging.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:31419747] [10.1016/j.saa.2019.117456]

72. Gaofei Wei, Liangfeng Huang, Yali Jiang, Yifeng Shen, Zeqian Huang, Yanjuan Huang, Xiaoqi Sun, Chunshun Zhao.  (2019)  Lenvatinib-zinc phthalocyanine conjugates as potential agents for enhancing synergistic therapy of multidrug-resistant cancer by glutathione depletion.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:30856406] [10.1016/j.ejmech.2019.02.065]

73. Lei Wang, Qi Xia, Ruiyuan Liu, Jinqing Qu.  (2018)  A red fluorescent probe for ribonucleic acid (RNA) detection, cancer cell tracing and tumor growth monitoring.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2018.07.018]

74. Liangfeng Huang, Gaofei Wei, Xiaoqi Sun, Yali Jiang, Zeqian Huang, Yanjuan Huang, Yifeng Shen, Xiaoyu Xu, Yunhui Liao, Chunshun Zhao.  (2018)  A tumor-targeted Ganetespib-zinc phthalocyanine conjugate for synergistic chemo-photodynamic therapy.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:29627724] [10.1016/j.ejmech.2018.03.077]

75. Lei Wang, Qi Xia, Ruiyuan Liu, Jinqing Qu.  (2018)  Real-time imaging of cancer cell generations and monitoring tumor growth using a nucleus-targeted red fluorescent probe.  Journal of Materials Chemistry B,  6  (15): (2340-2346).  [PMID:32254573] [10.1039/C8TB00101D]

76. Chunyu Yang, Wei Guo, Na An, Liru Cui, Ting Zhang, Ruihan Tong, Yuhua Chen, Huiming Lin, Fengyu Qu.  (2015)  Enzyme-sensitive magnetic core–shell nanocomposites for triggered drug release.  RSC Advances,  5  (98): (80728-80738).  [PMID:] [10.1039/C5RA15026D]

77. Haocong Zhang, Liangbi Xiang, Hong Yuan, Hailong Yu.  (2024)  ARL11 knockdown alleviates spinal cord injury by inhibiting neuroinflammation and M1 activation of microglia in mice.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,      [PMID:39307293] [10.1016/j.bbadis.2024.167522]

78. Yan Shi, Yufeng Yang, Juntong Liu, Jinling Zheng.  (2024)  Avicularin Treatment Ameliorates Ischemic Stroke Damage by Regulating Microglia Polarization and its Exosomes via the NLRP3 Pathway.  Journal of Integrative Neuroscience,  23  (11): (196).  [PMID:39613475] [10.31083/j.jin2311196]

79. Wei Yao, Yihui Wang, Xin Zhang, Yuhe Lin.  (2024)  B3GNT5 is a novel marker correlated with malignant phenotype and poor outcome in pancreatic cancer.  iScience,      [PMID:39319269] [10.1016/j.isci.2024.110889]

80. Tian Chunyan, Liu Qi, Zhang Xiaoyu, Li Zhuying.  (2024)  Blocking group 2 innate lymphoid cell activation and macrophage M2 polarization: potential therapeutic mechanisms in ovalbumin-induced allergic asthma by calycosin.  BMC Pharmacology & Toxicology,  25  (1): (1-12).  [PMID:38650035] [10.1186/s40360-024-00751-9]

81. Yumeng Gao, Jing Wu, Jian Shen, Yan Xu, Lu Li, Wentao Wang, Ninglin Zhou, Ming Zhang.  (2024)  Chitosan modified magnetic nanocomposite for biofilm destruction and precise photothermal/photodynamic therapy.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38219940] [10.1016/j.ijbiomac.2024.129402]

82. Huang Rongfu, Yao Jianfeng, Liu Lei, Li Hua, Huang Baoshan.  (2025)  Comprehensive analysis of LRRC42 as a potential biomarker and key cellular processes in cancer development.  Scientific Reports,  15  (1): (1-12).  [PMID:39939664] [10.1038/s41598-025-88467-6]

83. Zhang Jin, Maimaiti Aynuer, Chang Xihan, Sun Pengcheng, Chang Xiaohan.  (2024)  DDR1 promotes metastasis of cervical cancer and downstream phosphorylation signal via binding GRB2.  Cell Death & Disease,  15  (11): (1-12).  [PMID:39567474] [10.1038/s41419-024-07212-5]

84. Jingwen Shi, Wenda Jing, Yueyun He, Ying Huang.  (2024)  Decreased expression of KLF6 in ectopic endometrial stromal cells contributes to endometriosis progression by targeting CTNNB1.  CELLULAR SIGNALLING,      [PMID:38761988] [10.1016/j.cellsig.2024.111230]

85. Hao Wang, Lei Zhang, Yunxiao Shang.  (2024)  DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1.  Biology Direct,      [PMID:39533404] [10.1186/s13062-024-00557-z]

86. Tong Zhang, Bin Xu.  (2025)  Didymin Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cells by Modulating the PI3K/Akt Pathway.  NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL,      [PMID:39849840] [10.1080/01635581.2025.2454050]

87. Wentao Hu, Menghan Wang, Guifang Sun, Limin Zhang, Hong Lu.  (2024)  Early B Cell Factor 3 (EBF3) attenuates Parkinson's disease through directly regulating contactin-associated protein-like 4 (CNTNAP4) transcription: An experimental study.  CELLULAR SIGNALLING,      [PMID:38479556] [10.1016/j.cellsig.2024.111139]

88. Zhihang Zhang, Yalan Luo, Xijing Zhuang, Haifeng Gao, Qi Yang, Hailong Chen.  (2024)  Emodin alleviates lung injury via the miR-217-5p/Sirt1 axis in rats with severe acute pancreatitis.  JOURNAL OF PHARMACOLOGICAL SCIENCES,      [PMID:39313277] [10.1016/j.jphs.2024.08.007]

89. Wang Song, Bao Ning, Li Mohan, Liu Dongwei, Tao Liming.  (2024)  Ets2 Exacerbates Diabetic Retinopathy by Aggravating the Proliferation of Endothelial Cells and Inflammatory Response.  BIOCHEMICAL GENETICS,      [PMID:39432129] [10.1007/s10528-024-10938-8]

90. Liu Sishi, Gao Man, Zhang Xue, Wei Jun, Cui Hong.  (2024)  FOXP2 overexpression upregulates LAMA4 expression and thereby alleviates preeclampsia by regulating trophoblast behavior.  Communications Biology,  7  (1): (1-12).  [PMID:39487340] [10.1038/s42003-024-07149-7]

91. Qi Zhao, Ran Zhang, Yu Wang, Tiegang Li, Jinqi Xue, Zhiguang Chen.  (2024)  FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-κB signaling axis.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,      [PMID:38960057] [10.1016/j.bbadis.2024.167331]

92. Guangyu Zhou, Pai Liu, Chen Zhang, Qun Huang, Zixia Zhao, Si Wu, Detian Li, Hongbo Liu.  (2024)  HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease.  FASEB JOURNAL,  38  (4): (e23470).  [PMID:38354035] [10.1096/fj.202301429R]

93. Zhen Xu, Yilin Guo, Lu Wang, Jinquan Cui.  (2024)  HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling.  EXPERIMENTAL CELL RESEARCH,      [PMID:38266865] [10.1016/j.yexcr.2024.113949]

94. Xiaohan Pan, Peng Wang, Jiahui Gu, Yuxiu Wang, Qingqing Li, Wenpeng Zhao, Shu Wang, Jingxin Gou, Xinyu Fan.  (2024)  Improved epirubicin delivery selectivity to bladder cancer achieved by functionalized hydroxyethyl starch-based prodrug.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39733903] [10.1016/j.ijbiomac.2024.139275]

95. Jiaojiao Li, Qing Du, Jiangling Wan, Deng-Guang Yu, Fei Tan, Xiangliang Yang.  (2024)  Improved synergistic anticancer action of quercetin and tamoxifen citrate supported by an electrospun complex nanostructure.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2024.112657]

96. Hou Xiaolu, Hu Guoling, Wang Heling, Yang Ying, Sun Qi, Bai Xiuping.  (2025)  Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes.  Journal of Cardiovascular Translational Research,      [PMID:40095198] [10.1007/s12265-025-10602-5]

97. Weipeng Chen, Ke Zhou, Zhixin Wu, Linsen Yang, Yahui Xie, Xue Meng, Ziguang Zhao, Liping Wen.  (2024)  Ion-Concentration-Hopping Heterolayer Gel for Ultrahigh Gradient Energy Conversion.  Journal of the American Chemical Society,      [PMID:38603609] [10.1021/jacs.4c01036]

98. Ran Sun, Yan-Fang Wang, Xue Yang.  (2024)  Knockdown of IFIT3 ameliorates multiple sclerosis via selectively regulating M1 polarization of microglia in an experimental autoimmune encephalomyelitis model.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:38232539] [10.1016/j.intimp.2024.111501]

99. Jianfeng Ye, Cheng Qiu, Lexi Zhang.  (2024)  Knockdown of Leucine-rich alpha-2-glycoprotein 1 alleviates renal ischemia-reperfusion injury by inhibiting NOX4-mediated apoptosis, inflammation, and oxidative stress.  EXPERIMENTAL CELL RESEARCH,      [PMID:39566877] [10.1016/j.yexcr.2024.114341]

100. Ping Li, Lili Yuan, Ying Jiang, Yue Chen, Manyu Zhang, Ling Jiang, Pengling Ge.  (2025)  Liquiritin as a Tumor Suppressor Prevents the Development of Breast Cancer via the Epidermal Growth Factor Receptor/Mitogen-Activated Protein Kinase 8 Signaling Pathway.  DNA AND CELL BIOLOGY,      [PMID:40014434] [10.1089/dna.2024.0249]

101. Bo Li, Wei-Wei Yang, Bo-Chen Yao, Qing-Liang Chen, Li-Li Zhao, Yan-Qiu Song, Nan Jiang, Zhi-Gang Guo.  (2025)  Liriodendrin alleviates myocardial ischemia‑reperfusion injury via partially attenuating apoptosis, inflammation and mitochondria damage in rats.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,  55  (4): (1-12).  [PMID:39981888] [10.3892/ijmm.2025.5506]

102. Hailiang Li, Zheng Ma, Wanfu Yang, Yifan Zhang, Jinping Sun, Haifeng Jiang, Faxuan Wang, Li Hou, Hechun Xia.  (2025)  Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.  Frontiers in Pharmacology,      [PMID:40166471] [10.3389/fphar.2025.1563865]

103. Shuang Bai, Shao-Kang Sun, Zhen-Qi Xu, Ying-Bin Yan.  (2024)  Modulation of the malignant behavior of tongue squamous cell carcinoma cells by matrix metallopeptidase 25 through the NF-κB pathway.  HISTOLOGY AND HISTOPATHOLOGY,      [PMID:39668749] [10.14670/HH-18-852]

104. Keke Huang, Wenhan Fu, Anquan Wang, Gongwen Du, Hao Tang, Li Yin, Zongsheng Yin, Weilu Gao.  (2024)  MSRB2 Ameliorates H2O2-induced Chondrocyte Oxidative Stress and Suppresses Apoptosis in Osteoarthritis.  IMMUNOLOGICAL INVESTIGATIONS,      [PMID:38638027] [10.1080/08820139.2024.2343898]

105. Rui Hou, Yadong Wang, Shiyao Cao, Xinrui Sun, Luo Jiang.  (2024)  N6-methyadenosine modified KREMEN2 promotes tumorigenesis and malignant progression of high grade serous ovarian cancer.  LABORATORY INVESTIGATION,      [PMID:38615731] [10.1016/j.labinv.2024.102059]

106. Luhaoran Sun, Zeyu Li, Peng Shu, Min Lu.  (2024)  N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression.  CANCER SCIENCE,      [PMID:39105355] [10.1111/cas.16296]

107. Zhang Ke, Zhang Hailing, Wang Bing, Gao Shanshan, Sun Caiping, Jia Cong, Cui Jinquan.  (2024)  NR2F1 overexpression alleviates trophoblast cell dysfunction by inhibiting GDF15/MAPK axis in preeclampsia.  Human Cell,      [PMID:39007956] [10.1007/s13577-024-01095-6]

108. Ruan Yuxia, Qiao Jianghua, Wang Jiabin, Liu Zhenzhen.  (2024)  NREP, transcriptionally upregulated by HIF-1α, aggravates breast cancer cell growth and metastasis by promoting glycolysis.  Cell Death Discovery,  10  (1): (1-13).  [PMID:38697993] [10.1038/s41420-024-01951-2]

109. Guoqiang Xing, Hekai Chen, Zhiyue Guo, Yu Cui, Yongyuan Li, Jianwei Shen.  (2024)  OTUD6B promotes cholangiocarcinoma growth by regulating STAT3 phosphorylation through deubiquitination of PTK2.  CELL BIOLOGY INTERNATIONAL,      [PMID:39192576] [10.1002/cbin.12234]

110. Jing Qiu, Yi-Han Wang, Xiu-Ming Wang, Hui-Sheng Chen.  (2024)  PI3Kδ inhibition alleviates the brain injury during cerebral ischemia reperfusion via suppressing pericyte contraction in a TNF-α dependent manner.  EXPERIMENTAL NEUROLOGY,      [PMID:38365134] [10.1016/j.expneurol.2024.114728]

111. Sun Wei, Zhao Bo, He Zhong, Chang Lihua, Song Wei, Chen Yingying.  (2025)  PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy.  Communications Biology,  8  (1): (1-14).  [PMID:39810019] [10.1038/s42003-024-07334-8]

112. Tingyu Qin, Yingnan Lv, Xiangying Xi, Zhipeng Wu.  (2024)  PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy.  BIOCHEMICAL PHARMACOLOGY,      [PMID:38906226] [10.1016/j.bcp.2024.116374]

113. Hang Hu, Ting Yuan, Jiahao Qian, Xinya Lu, Xi Chen, Xiaoya Sun, Yuchen Lin, Yuxiang Tang, Qingbo Xu, Tianyu Zhu, Yu Hu, Defeng Xu.  (2024)  Polyethylene glycol modified protamine-chlorin e6 conjugate nanoparticles for enhanced cancer photodynamic therapy.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2024.112871]

114. Zhu Xiao-Yu, Li Pi-Song, Qu Hui, Ai Xing, Zhao Zi-Ting, He Jia-Bei.  (2025)  Replication factor C4, which is regulated by insulin-like growth factor 2 mRNA binding protein 2, enhances the radioresistance of breast cancer by promoting the stemness of tumor cells.  Human Cell,  38  (3): (1-14).  [PMID:40053279] [10.1007/s13577-025-01197-9]

115. Congna Zi, Yulei Wei, Ying Zhu, Juan Fan.  (2025)  RGS12 is a target of penehyclidine hydrochloride that enhances oxidative stress and ferroptosis in a model of myocardial ischemia/reperfusion injury by inhibiting the Nrf2 pathway.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,  55  (3): (1-15).  [PMID:39930821] [10.3892/ijmm.2025.5493]

116. Wen Zhong, Huanan Jia, Haiyan Zhu, Yuan Tian, Wei Huang, Qiyue Yang.  (2024)  Sarcopenia is attenuated by mairin in SAMP8 mice via the inhibition of FAPs fibrosis through the AMPK-TGF-β-SMAD axis.  GENE,      [PMID:39159793] [10.1016/j.gene.2024.148873]

117. Xiaoliang Dong, Lu Qu, Bingxin Wang, Xiaowei Sha, Bo Wu, Yudong Sun, Xiaohua Pan, Juan Xiong, Jia Sun, Li-Long Pan.  (2024)  Shizukaol C alleviates trimethylamine oxide-induced inflammation through activating Keap1-Nrf2-GSTpi pathway in vascular smooth muscle cell.  PHYTOMEDICINE,      [PMID:38564920] [10.1016/j.phymed.2024.155403]

118. Zhaohui Shi, Tianfeng Zhao, Dingbo Li, Chong Wang, Yanjie Luo, Yangshan Zheng.  (2024)  Silencing of forkhead box C1 reduces nasal epithelial barrier damage in mice with allergic rhinitis via epigenetically upregulating secreted frizzled-related protein 5.  MOLECULAR IMMUNOLOGY,      [PMID:38422887] [10.1016/j.molimm.2024.02.011]

119. Yu Shan, Yang Jinghui, Zhang Rui, Guo Qian, Wang Lu.  (2024)  SLC15A3 is transcriptionally regulated by HIF1α and p65 to worsen neuroinflammation in experimental ischemic stroke.  MOLECULAR NEUROBIOLOGY,      [PMID:38717559] [10.1007/s12035-024-04191-8]

120. Yun Zhou, Song Yue, Lihua Li, Jiahua Zhang, Lei Chen, Jun Chen.  (2024)  SMPDL3B is palmitoylated and stabilized by ZDHHC5, and its silencing aggravates diabetic retinopathy of db/db mice: Activation of NLRP3/NF-κB pathway.  CELLULAR SIGNALLING,      [PMID:38266744] [10.1016/j.cellsig.2024.111064]

121. Huijuan Zhang, Jianli Qiu, Qianyi Zhao, Yong Zhang, Haitao Zheng, Ziying Dou, Yongbin Yan.  (2024)  Tanshinone IIA alleviates bleomycin-induced pulmonary fibrosis by inhibiting Zbtb16.  PULMONARY PHARMACOLOGY & THERAPEUTICS,      [PMID:38191069] [10.1016/j.pupt.2024.102285]

122. Liting Wen, Xiaoxia Zeng, Zengping Lin, Peixiong Chen, Dapeng Zhao, Xianhai Zeng.  (2025)  TFAP2B governs the regulation of SIRT1 to inhibit osteoclast-induced bone destruction..  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,      [PMID:39946982] [10.1016/j.bbrc.2025.151410]

123. Mao-Cheng Sun, Yu-Xin Chen, Xiu-Juan Fan, Ying-Di Wang, Tiehua Zhang, Changhui Zhao.  (2024)  The anti-biofilm mechanism of reuterin against Staphylococcus aureus and its potential application on milk-contact material surfaces.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.105744]

124. Feng-Xia Qu, Xiao Guo, Xiao-Jun Liu, Shu-Wen Zhang, Yue Xin, Jing-Yuan Li, Rong Wang, Chen-Ji Xu, Hai-Ying Li, Chang-Hong Lu.  (2024)  Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway.  ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS,      [PMID:39271097] [10.1016/j.abb.2024.110153]

125. Changyun Yu, Chen Zhang, Qianqian Zhang, Cai Zhang, Jingjie Han, Jinying Li.  (2024)  TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.  iScience,      [PMID:39790556] [10.1016/j.isci.2024.111590]

126. Yuankun Chen, Gaofeng Pan, Yijun Yang, Haifeng Wu, Minhua Weng, Qiuping Wu, Yufeng Gao, Wenting Li.  (2024)  Tumor exosomal RNPEP promotes lung metastasis of liver cancer via inducing cancer-associated fibroblast activation.  CANCER SCIENCE,      [PMID:39658708] [10.1111/cas.16417]

127. Zhang Lexi, Ye Jianfeng, Qiu Cheng.  (2025)  Twist2 knockdown alleviates renal ischemia–reperfusion injury by maintaining mitochondrial function and enhancing mitophagy through Bnip3.  Human Cell,  38  (2): (1-16).  [PMID:39918659] [10.1007/s13577-025-01177-z]

128. Dan LI, Le WANG, Shufeng SHI, Xiaofeng DENG, Xuehan ZENG, Yunong LI, Shulin LI, Peng BAI.  (2024)  UBL4A alleviates the progression of intracerebral hemorrhage by regulating oxidative stress and mitochondrial damage.  EXPERIMENTAL ANIMALS,      [PMID:38852999] [10.1538/expanim.24-0035]

129. Yanhua Zhen, Dongdong Li, Yulu Meng, Zeyu Xing, Jiahe Zheng.  (2025)  Unveiling the roles of HIPK2 in atherosclerosis: Insights into the β-catenin/STAT1 signaling cascade and the involvement of SENP1.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40164339] [10.1016/j.bcp.2025.116911]

130. Congna Zi, Xian Ma, Maodong Zheng, Ying Zhu.  (2024)  VDAC1-NF-κB/p65-mediated S100A16 contributes to myocardial ischemia/reperfusion injury by regulating oxidative stress and inflammatory response via calmodulin/CaMKK2/AMPK pathway.  EUROPEAN JOURNAL OF PHARMACOLOGY,      [PMID:39613175] [10.1016/j.ejphar.2024.177158]

131. Meng Hui, Li Ling, Nan Manman, Ding Yi, Li Yizhen, Zhang Mingzhi.  (2024)  ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancer.  ONCOGENE,      [PMID:39261658] [10.1038/s41388-024-03154-6]

132. Zuhan Chen, Beizhi Jiang, Huanjing Bi, Chongfeng Wang, Yanyan Liu, Jingwen Wang, Ying Wang, Zejiaxin Niu, Ruiyang Ma, Boqing Dong, Xiaoyang Yu, Fang Xie, Xiaoming Ding.  (2025)  Construction of multilayer multifunctional hydrogel microspheres with natural macromolecules, tannic acid, and copper for enhanced diabetic wound healing.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.165896]

133. Junwu Wei, Tian Xia, Jing Xia, Tianyu Gao, Guiyuan Zhang, Peng Huang, Xiaohong Li.  (2025)  Biofilm-triggered interfacial assembly of dual-porphyrin heterojunctions for chemo-/sonodynamic treatment of pyomyositis.  Acta Biomaterialia,      [PMID:40752855] [10.1016/j.actbio.2025.07.069]

134. Sihang Li, Xun Zhou, Jiahao Cui, Xingjian Zou, Zijian Li, Wirote Youravong, Ming Li, Haihua Wang, Zhenyu Li.  (2025)  Non-contaminative MIL-53(Fe)-anchored Ultrafiltration Membrane for Apple Juice Sterilization: Anti-biofouling Performance and Mechanism.  JOURNAL OF FOOD ENGINEERING,      [PMID:] [10.1016/j.jfoodeng.2025.112747]

135. Liming Hou, Xiaoming Wang, Min Bai, Qian Li, Wei Zhang, Hui Su, Yan Liu.  (2025)  LRRC8A/TRIM21 axis exacerbates myocardial ischemia/reperfusion injury by blocking FAK/NF-κB pathway.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40619028] [10.1016/j.bcp.2025.117110]

136. Dapeng Lu, Lin Ma, Qingyue Zhang, Chengzhong Xing, Yanke Li.  (2025)  BDH2 promotes GLIPR1 promoter methylation and thus increases 5-FU sensitivity in colorectal cancer.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40659127] [10.1016/j.bcp.2025.117153]

137. Huanchen Yao, Dayang Wang, Jiashuo Ye, Hailin Cong, Bing Yu.  (2025)  Investigation on the antitumor effects of fisetin extracted from Hedyotis diffusea willd based on network pharmacology and experimental validation.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:40712814] [10.1016/j.jep.2025.120288]

138. Zhongcheng Zhu, Xiaolin Dou, Qizhen Chen, Yebin Lu.  (2025)  Knockdown of Nr4a3 mitigates acute pancreatitis-induced injury by modulating Btg2 to reduce oxidative stress, mitochondrial damage, and apoptosis.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:40706207] [10.1016/j.intimp.2025.115269]

139. Xiaolin Dou, Zhongcheng Zhu, Qizhen Chen, Yebin Lu.  (2025)  Sirt1-Mediated Transcriptional Inhibition of Nr4a3 Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury.  FASEB JOURNAL,  39  (14): (e70867).  [PMID:40699943] [10.1096/fj.202501210R]

140. Jin-Xian Fu, Jiao Jiao, Qing-Yan Gai, Yu-Jie Fu, Mo-Nan Wen, Xiao-Qing Wang, Jing He.  (2025)  Sporopollenin-chitosan microspheres loaded with an endophytic fungus Talaromyces neorugulosus R-209 for promoting development and controlling root rot in pigeon pea.  JOURNAL OF PLANT PHYSIOLOGY,      [PMID:40700996] [10.1016/j.jplph.2025.154569]

141. Lanlan Cheng, Jie Zhang, Yungai Xiang, Li Tan.  (2025)  RUNX3 drives HTR-8/SVneo cell ferroptosis and spontaneous abortion: involvement of the suppression of GDF15 transcriptional activity.  MOLECULAR AND CELLULAR ENDOCRINOLOGY,      [PMID:40712695] [10.1016/j.mce.2025.112618]

142. Rui Zhou, Xiuzhu Wang, Nannan Li.  (2025)  Overexpression of PBX1 attenuates oxidative stress and apoptosis in diabetic cardiomyopathy by transcriptionally inhibiting TXNIP.  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY,      [PMID:40614857] [10.1016/j.biocel.2025.106828]

143. Man Cai, Liangyu Wang, Miao Sun, Meixi Liu, Yingchun Liu.  (2025)  PRMT6 Inhibits Malignant Progression of Melanoma by Antagonizing Trimethylation of Histone H3K4 to Downregulate ALDH1A1 Levels.  Pigment Cell & Melanoma Research,  38  (4): (e70034).  [PMID:40635376] [10.1111/pcmr.70034]

144. Zhang Xiaojun, Wang Fang, Dai Yuna, Gao Zhaoyu, He Jianchao.  (2025)  α-Cyperone affects the development and chemosensitivity of breast cancer by modulating TRIM24.  IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL,      [PMID:40634623] [10.1007/s11626-025-01067-6]

145. Xinming Wang, Yiming Zhong, Bei Qian, Shixing Huang, Qiang Long, Haonan Zhang, Qiang Zhao, Xiaofeng Ye.  (2025)  Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.  Materials Today Bio,      [PMID:40893381] [10.1016/j.mtbio.2025.102205]

146. Shaohua Liu, Chen Wang, Chaoran Wang, Yuanyuan Deng, Yanping Tang, Boshi Tian, Hongjun Xia, Yahong Chen, Lin Jin, Zhengxiao Guo, Piaoping Yang.  (2025)  A biodegradable self-cascading copper-based nanozyme for augmented cancer catalytic therapy and cuproptosis.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40829233] [10.1016/j.jcis.2025.138692]

147. Siqi Yu, Fudong Wang, Yuan Zhang, Xiaofeng Wang, Hongyu Zhao, Qiang Zheng.  (2025)  Beneficial effects of dihydrocapsaicin on paraquat-induced acute kidney injury: role of Sox9/Sesn2 axis-mediated autophagy.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:40834759] [10.1016/j.ecoenv.2025.118871]

148. Meng Lan, Fansu Meng, Lanwen Gao, Anil K. Giri, Makiya Nishikawa, Kosuke Kusamori, Jaiwoo Lee, Mulazim Hussain Asim, Shumaila Arshad, Honghui Gu, Qi Li, Lina Yang, Zhong Chen, Zhenjiang Yang, Jiajia Qin, Yu Cai.  (2025)  Preparation of baicalin nano prodrug and its effect on inhibiting metastasis of triple-negative breast cancer.  Biomaterials Advances,      [PMID:40850054] [10.1016/j.bioadv.2025.214464]

149. Yijun Yang, Nengyi Wang, Yuankun Chen, Tianpeng Ma, Minhua Weng, Haifeng Wu, Qiuping Wu, Yiqiang Xie, Chuanwu Zhu, Wenting Li.  (2025)  IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation.  JOURNAL OF BIOLOGICAL CHEMISTRY,      [PMID:40769409] [10.1016/j.jbc.2025.110560]

150. Yujing Wang, Yuanxin Xu, Yilin Liu, Jindan Lin, Xincai Hong, Shuang Yan.  (2025)  Pirin knockdown alleviates the progression of metabolic dysfunction-associated steatotic liver disease by inhibiting hepatic lipid deposition, inflammation, and fibrosis.  MOLECULAR AND CELLULAR ENDOCRINOLOGY,      [PMID:40754200] [10.1016/j.mce.2025.112632]

151. Ping Liu, Jiantao Jia, Yinliang Lu, Hanmin Tang, Chengyi Gao, Suxia Han.  (2025)  S100A11 mediates the protective effects of edaravone dexborneol on docetaxel-induced cognitive impairment in rats by inhibiting the MAPK signaling pathway.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:40780535] [10.1016/j.taap.2025.117504]

152. Shi Zhaohui, Zhao Tianfeng, Wu Yongjin, Tang Zhiyuan, Wang Zaixing, Li Dingbo, Wang Chong.  (2025)  Associated transcription factors of allergic rhinitis: SP1 aggravates nasal epithelial barrier damage.  JOURNAL OF IMMUNOLOGY,      [PMID:40849888] [10.1093/jimmun/vkaf207]

153. Chengxiang Yan, Haijiang Dong, Zhibin Li, Xinhao Cheng, Ximei Wang.  (2025)  NNMT Enhances Invasive and Migratory Capacity of Keloid Fibroblasts and M2 Macrophage Polarization.  ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS,      [PMID:40818625] [10.1016/j.abb.2025.110593]

154. Yiqi Wang, Xiuhua Zhang, Jiannan Zhang, Mingbo Zhao, Yang Chong, Quankuan Gu, Xianglin Meng, Mingyan Zhao.  (2025)  ANAPC5 mitigates acute lung injury through regulating macrophage M1/M2 polarization via the EGFR/CD24 axis.  CELLULAR IMMUNOLOGY,      [PMID:40834712] [10.1016/j.cellimm.2025.105013]

155. Yu Zhang, Nannan Tong, Siyu Hao, He Ma, Yuzhen Li.  (2025)  ELF3 promotes the development of psoriasis through transcriptional up-regulation of ADAM8 expression.  IMMUNOLOGY LETTERS,      [PMID:40784441] [10.1016/j.imlet.2025.107069]

156. Lei Wang, Yufeng Bai, Dan Ma, Wenxiu Liu, Zhiyu Shi, Chunnan Liu, Meng Zhao, Huiying Wang, Liying Luo, Jinyu Chi.  (2025)  TEA domain transcription factor 3 suppresses aortic and left ventricular remodeling via transcriptional activation of PDZ domain containing 1.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40939874] [10.1016/j.bcp.2025.117329]

157. Ruixi Li, Qiang Tao, Jiandong Zha, Shikai Wang, Xiaozhun Huang, Jicai Wang, Hang Zhai, Shengjie Hong, Guangquan Zhang.  (2025)  UHRF1 ameliorates liver cirrhosis through suppressing macrophage M1 polarization by catalyzing HMGA2 promoter methylation.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40976429] [10.1016/j.bcp.2025.117357]

158. Jie Chen, Naiquan Yang, Yi Xu, Yan Ji, Zheng Qian, Jing Sun, Qiuyang Zhang, Qingping Xiong, Changjiang Pan.  (2025)  Construction of an anticoagulant coating mimicking extracellular matrix for better surface blood compatibility and endothelialization of polyurethanes.  POLYMER,      [PMID:] [10.1016/j.polymer.2025.129172]

159. Kai Liu, Hong Sun, Hong Wang, Junbo Zheng, Xiuzhen Wang, Xin Wang, Yeting Hou, Qian Ye, Ji Li.  (2025)  Ellagic acid alleviates sepsis-induced intestinal injury by modulating gut microbiota and NF-κB-mediated MLCK/MLC signaling pathway.  MICROBIAL PATHOGENESIS,      [PMID:40930441] [10.1016/j.micpath.2025.108026]

160. Pei Lipeng, Zhu Yan, Li Wenpeng, Xu Bin, Sun Jingli.  (2025)  Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription.  MOLECULAR MEDICINE,  31  (1): (1-15).  [PMID:39901144] [10.1186/s10020-025-01082-z]

161. Hu Guangquan, Chen Jin, Chen Min, Yang Kai, Wang Yuchen, Ma Ziyang, Bao Huangxin, Ding Xiaojie.  (2024)  Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways.  Journal of Cardiovascular Translational Research,      [PMID:38990461] [10.1007/s12265-024-10533-7]

162. Yishi Lu, Ziyue Zu, Nan Zhong, Yang Li, Xuan Sha, Shangyu Lu, Jie Zhang, Hanyao Sun, Xi Luo, Ziqing Xu, Feiyun Wu, Yuxia Tang, Shouju Wang.  (2025)  Spatiotemporal Blockade of Autophagy and Macropinocytosis in Pancreatic Cancer via Lysosomal-Activated Nanoreactors.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202502220]

163. Yujing You, Chenhao Tang, Gang Zhang, Zhiqiang Jiang, Zhongda Lv.  (2018)  Thermo-modulated Hela cell release from an elastic and biocompatible hydrogel.  JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS,  107  (6): (1786-1791).  [PMID:30440098] [10.1002/jbm.b.34271]

164. Reziwanguli Wusiman, Shayila Haimiti, Hanikezi Abuduaini, Miaoyan Yang, Yitian Wang, Meijun Gu, Ali Sailike, Lei Gao.  (2025)  Increased SUMO-activating enzyme subunit 1 promotes glycolysis and fibrotic phenotype of diabetic nephropathy.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40194606] [10.1016/j.bcp.2025.116920]

165. Cong Feng, Yue Jiang, Yi Wang, Yuehui Zhang, Yu Liu, Jia Li.  (2025)  Protocatechualdehyde improves cyclophosphamide-induced premature ovarian insufficiency by inhibiting granulosa cell apoptosis and senescence through the SIRT1/p53 axis.  REPRODUCTIVE TOXICOLOGY,      [PMID:40228705] [10.1016/j.reprotox.2025.108903]

166. Tao Bai, Luhao Wang, Zhentao Qiao, Zhiwei Wang.  (2025)  Cuproptosis, a potential target for the therapy of Diabetic Critical Limb Ischemia.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:40246253] [10.1016/j.freeradbiomed.2025.04.022]

167. Kun Zhang, Kehui Yang, Lingyuan Zeng, Yang Xiao, JinGui Yu.  (2025)  Rab32 protects mitochondrial function by anchoring Fancd2 and mediates the protective effect of penehyclidine hydrochloride against myocardial ischemia-reperfusion injury.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:40286784] [10.1016/j.intimp.2025.114697]

168. Ding-Yi Zhang, Meng-Xi Wang, Chuang Cai, Wei-Wei Cheng, Yin-Jia Cheng, Wen-Long Liu, Rong Huang, Ai-Qing Zhang, Si-Yong Qin.  (2025)  Bacterial membrane-anchored lipopeptide/MXene nanoplatform for tri-modal therapy toward bacteria-infected diabetic wound.  Biomaterials Advances,      [PMID:40373534] [10.1016/j.bioadv.2025.214324]

169. Liangliang Chen, Siyuan Chen, Zhanbo Yi, Xianjiang Wu, Shuwen Zhong, Leiqiang Mao, Zesheng Wang, Qi Shuai, Xin Li.  (2025)  Oligosaccharide and alkyl chain-modified polyethyleneimines for efficient siRNA delivery.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2025.113988]

170. Zhi-Hao Wang, Xuejiao Zeng, Shuhao Zhang, Hailong Li, Jianchao Zhou, Yefei Yang, Wanting Huang, Fengqin Zhao, Zhongyang Liu, Junjie Liu, Yurong Hu, Jinjin Shi.  (2025)  Acoustic-Magnetic Responsive Nanomotor Augments Oral Drug Delivery by Gastrointestinal Site Navigation and Mucus Layer Penetration.  ACS Nano,      [PMID:40299707] [10.1021/acsnano.4c07866]

171. Xinxin Chen, Jiang Sun, Tingxian Ye, Fanzhu Li.  (2025)  Neutrophil-Camouflaged Stealth Liposomes for Photothermal-Induced Tumor Immunotherapy Through Intratumoral Bacterial Activation.  Pharmaceutics,  17  (5): (614).  [PMID:40430905] [10.3390/pharmaceutics17050614]

172. Guanrong Li, Renhao Ni, Zheyuan Shi, Haijiao Mao, Yang Luo, Xu Cao, Chi Zhang, Yuetian Liu, Zhanping Jin, Jun Chen, Jun Fu, Hua Zhang, Yingchun Zhu.  (2025)  Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40345284] [10.1016/j.ijbiomac.2025.144042]

173. Junli Han, Lianghe Wang, Li Wang, Hua Lei.  (2025)  5-Hydroxytryptamine Limits Pulmonary Arterial Hypertension Progression by Regulating Th17/Treg Balance.  BIOLOGICAL & PHARMACEUTICAL BULLETIN,  48  (5): (555-562).  [PMID:40350297] [10.1248/bpb.b24-00831]

174. Yancen Liu, Chuang Ma, Jinlong Tian, Bin Li, Jin Zhao.  (2025)  Pulsed electric field-treated malvacin-3-O-galactoside and whey protein complexes alleviate silica-induced pulmonary fibrosis by promoting cellular mitochondrial autophagy and inhibiting cellular pyroptosis.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2025.106895]

175. Wen Jingli, Geng Lei, Wang Ruohan, Zhang Xiaolei, Sui Yanmin, Liu Xiaofang, Han Xin.  (2025)  Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells.  JOURNAL OF MOLECULAR HISTOLOGY,  56  (3): (1-14).  [PMID:40418235] [10.1007/s10735-025-10446-y]

176. Rui Kong, Jun Bai, Qing Yao, Xiaoqing Xu.  (2025)  DUSP14 attenuates airway inflammation and mucus hypersecretion in allergic asthma by regulating TAK1 activity.  IMMUNOLOGY LETTERS,      [PMID:40449853] [10.1016/j.imlet.2025.107047]

177. Wu Lin, Zhang Fangyuan, Chen Huanhuan, Zhao Gang.  (2025)  LSM12 promotes the lung squamous cell carcinoma progression through mediating alternative splicing of ARRB1.  Communications Biology,  8  (1): (1-15).  [PMID:40425760] [10.1038/s42003-025-08193-7]

178. Qingqing Chen, Ling Ouyang.  (2025)  Tumor suppressor FBXO11 drives ubiquitin proteasomal degradation of KIF2C to limit ovarian cancer progression and is transcriptionally repressed by ZNF217.  CELLULAR SIGNALLING,      [PMID:40447129] [10.1016/j.cellsig.2025.111910]

179. Qiu Yu, Ruan Huijie, Ji Decai, Cao Na.  (2025)  NEURL1 acts as a candidate suppressor in bladder cancer by down-regulating PDE9A.  IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL,      [PMID:40442542] [10.1007/s11626-025-01047-w]

180. Rongyan Zhu, Liu Yang, Yulan Li.  (2025)  TXNIP Participates in the Pathogenesis of PCOS by Regulating Glycolysis in Granulosa Cells.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,      [PMID:40499496] [10.1016/j.bbrc.2025.152149]

181. Jing Zhang, Xuewei Yang, Xing Zhao, Gang Luo, Hong Jiang.  (2025)  KLF3 aggravates renal fibrosis in chronic kidney disease through transcriptional activation of DDAH2.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40480524] [10.1016/j.bcp.2025.117033]

182. Congna Zi, Ying Zhu, Xian Ma, Yulei Wei.  (2025)  BASP1/HTRA2 axis, targeted by miR-7a-5p, exerted a pro-apoptosis role in myocardial ischemia/reperfusion injury.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:40484205] [10.1016/j.taap.2025.117437]

183. Ying Feng, Jiamei Yue, Si Fan, Jiayan Wu.  (2025)  The SOX18-OTUB1-YAP1 axis: a new endometriosis target.  Journal of Translational Medicine,      [PMID:40500704] [10.1186/s12967-025-06677-y]

184. Keda Shi, Liang Hu, Duote Cai, Xing Liu, Jilin Zheng, Dongxin Xu, Qunchen Yuan, Qianwen Xiong, Haoran Gong, Xiaoyang Zhu, Ning Hu, Chunlian Qin.  (2025)  Three-Dimensional-Printed Flexible Nanosilver Electrode Array for Parallel and Robust Intracellular Electrophysiological Recording.  ACS Nano,      [PMID:40365958] [10.1021/acsnano.5c01372]

185. Delong Meng, Qian Su, Kejuan Jia, Mengjie Jin, Wenting Liu, Shiqi Yang, Zhiqiang Su.  (2025)  ETV5 improves ischemic stroke by targeting HACE1/Nrf2 axis to inhibit microglia M1 polarization and neuron pyroptosis.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40562126] [10.1016/j.bcp.2025.117057]

186. Yun Tang, Jinghan Lin, Tingting Zhao, Lina Sun, Tingjiao Liu.  (2025)  CNTs-CaP/CS-AZ91D extracts induce CGRP production in dorsal root ganglion neurons to facilitate osteogenesis in rats.  Biomaterials Science,      [PMID:40546042] [10.1039/D4BM01635A]

187. Lei Zhang, Junjie Xu, Fujiang Cui, Jin Jin, Liwen Liu, Lei Wang, Yuxia Gao.  (2025)  Fxyd5 downregulation protects the heart from ischemia/reperfusion injury by suppressing myocardial inflammation.  TRANSPLANT IMMUNOLOGY,      [PMID:40912610] [10.1016/j.trim.2025.102282]

188. Chenguang Yao, Ting Tan, Jiangning Yan, Zijia Zhao, Romina Onintsoa Diarimalala, Junjie Wang, William Wang, Hanluo Li, Jingbiao Liu, Yanhong Wei, Kanghong Hu.  (2025)  In Vitro Study on the Antitumor Bioactivity of Anderson-Type Polyoxometalates.  CURRENT PHARMACEUTICAL DESIGN,  31  (42): (3416-3426).  [PMID:40265428] [10.2174/0113816128367617250323075703]

189. An-qi Tang, Xuechao Xu, Cao-wei Chen, Mengyuan Tan, Lu Gao, Zhen-quan Yang.  (2025)  Phage adsorption-driven colorimetric broad-spectrum detection of foodborne Enterobacter hormaechei using phage-modified NH2-MIL-88B(Fe) nanozyme.  FOOD CHEMISTRY,      [PMID:41061622] [10.1016/j.foodchem.2025.146616]

190. Zhai Yize, Duan Wenzhuo, Yang Ziqing, Yang Jianfei.  (2025)  Design of mesoporous silica nanoparticles with quercitrin hydrogels improves cardiac remodeling and myocardial infarction reprogramming.  JOURNAL OF MATERIALS SCIENCE,      [PMID:] [10.1007/s10853-025-11556-4]

191. Li Qingsheng, Liu Yuxi, Zhang Lin, Zheng Yi, Feng Xiaofan, Wang Yanjie.  (2025)  Cedrol impedes lung cancer metastasis by reducing tumor-associated macrophage polarization mediated by MYC-driven aerobic glycolysis.  Human Cell,  38  (6): (1-17).  [PMID:41071378] [10.1007/s13577-025-01299-4]

192. Tuxiu Xie, Jiakun Xiang, Yu He, Mi Tian, Wei Zhan, Ling-Yang Hua, Shuixiang Deng, Rui Pan, Yunling Gao, Ming Chen, Rongfeng K. Hu, Ye Gong, Zhi-Xiang Xu.  (2025)  An excitatory circuit in the ventrolateral periaqueductal gray drives hypometabolic state during acute systemic inflammation.  Cell Reports,      [PMID:41045458] [10.1016/j.celrep.2025.116394]

193. Jimin Cai, Jiacheng Zhang, Nan Wang, Yan Wang, Di Jia, Xin Ge.  (2025)  Interferon Regulatory Factor1 Deficiency Ameliorates Hemorrhagic Shock-Induced Kidney Injury Via IGFBP7/IGF1R Pathway.  JOURNAL OF SURGICAL RESEARCH,      [PMID:41092604] [10.1016/j.jss.2025.09.056]

194. Li Yuan, Liu Wenna, Fan Xushen, Wu Xinyi, Cao Mingbo, Li Xiuling, Wurita Amin, Sun Suofeng.  (2025)  FAIM modulates HCC progression via enhancing HMGA1 interaction with CDK7 and promoting its phosphorylation level.  Journal of Translational Medicine,  23  (1): (1-15).  [PMID:41094644] [10.1186/s12967-025-07148-0]

195. You Zhou, Kai Yang, Jian Wang, Ruijuan Guan, Wei Liu, Chaowei Wen, Liang Yuan, Tiange Zhang, Wei Feng, Yuanyuan Li, Jingyi Xu, Wenju Lu.  (2025)  MUC1 alleviates PM2.5-induced airway inflammation by inhibiting the IRAK4/NF-κB/NLRP3 mediated pyroptosis in airway epithelial cells.  Frontiers in Immunology,      [PMID:41181093] [10.3389/fimmu.2025.1653184]

196. Huanqing Song, Qingfei Hao, Jingjing Li, Yuanyuan Liu, Zhifang Huo, Ranran Si, Xiaoxia Feng, Chuan Zhou, Xiuyong Cheng.  (2025)  Overexpression of peroxiredoxin 6 in bone marrow-derived mesenchymal stem cells amplifies their in vivo effect on bronchopulmonary dysplasia by increasing mesencephalic astrocyte-derived neurotrophic factor secretion.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:41176133] [10.1016/j.taap.2025.117624]

197. Min Zhan, Qin Yi, Liang Yu, Qiankun Li, Murong Jiang, Dongsheng Wu, Mintao Jian, Hui Cao, Donghua Bin.  (2025)  Isopimpinellin: A Promising Treatment for Colitis-Related Colorectal Cancer That Targets ALOX5-Mediated Macrophage Polarization.  PHYTOTHERAPY RESEARCH,      [PMID:41047136] [10.1002/ptr.70065]

198. Mingxing Sui, Shuying Wu, Qingqing Song, Siyao Chen, Yingli Lu.  (2025)  FOXO6, Stabilized by METTL3-Mediated m6A Modification, Accelerates Polycystic Ovary Syndrome Progression by Transcriptional Activation of TXNIP.  FASEB JOURNAL,  39  (20): (e71141).  [PMID:41091548] [10.1096/fj.202502357R]

199. Li Ming-Ying, Zhang Xiao-Xia, Sun Xiao-Li, Wang Zhen-Yuan, Li Jie, Zhang Xue-Na.  (2025)  Impact of isoflurane anesthesia on astrocyte connexin 30 expression in adult rats and its possible implications for postoperative neurocognitive disorder.  EUROPEAN JOURNAL OF MEDICAL RESEARCH,  30  (1): (1-8).  [PMID:41177887] [10.1186/s40001-025-03245-4]

200. Shengming Wu, Chenlong He, Huawei Liu, Han Zhou, Jingwen Qin, Ming Yin, Muqing Yang, Wenjie Tang, Yilong Wang.  (2025)  Near infrared excitation of an upconversion nanoparticle@TiO2-nitrate system to generate nitrate radicals for deep tissue penetration in tumor catalytic therapy.  Acta Biomaterialia,      [PMID:41173132] [10.1016/j.actbio.2025.10.051]

201. Guo Yan, Liu Ying, Zhou Mingkai, Zhao Yulan.  (2025)  Srpx2 exerts multifaceted cardio-protection in septic cardiomyopathy: PI3K/AKT-dependent attenuation of mitochondrial oxidative stress, apoptotic signaling, and inflammatory response.  Human Cell,  39  (1): (1-17).  [PMID:41186620] [10.1007/s13577-025-01306-8]

202. Haizhou Qiu, Kunlin Chen, Yiwen Qiu, Yi Yang, Tao Wang, Li Jiang, Wentao Wang.  (2025)  CD44 and Mitochondria Dual-Targeted Polydopamine Nanoplatform for Combined Chemotherapy, Photothermal Ablation, and Immunogenic Cell Death Induction in Liver Cancer.  Journal of Materials Chemistry B,      [PMID:41218135] [10.1039/D5TB01901J]

203. Kangkang Zhi, Yi Shi, Weibing Lin, Huilan Yang, Yawen Zhu, Jiajia Cui, Wen Zhang, Junlong Wang, Ji Zhang.  (2025)  A natural oleanolic acid self-assembly system for curcumin: Structural insights, enhanced physicochemical properties, and synergistic antioxidant activity.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107842]

204. Yanqi Peng, Ji Wu, Ronghua Fan, Mingyue Ma, Xixin Wang, Yuzhen Pi, Xiqing Yue, Yanyu Peng.  (2025)  Almond Polysaccharide Ameliorates DSS-Induced Ulcerative Colitis in Mice by Restoring Intestinal Barrier Function and Modulating Gut Microbiota and SCFAs Metabolism.  Food Frontiers,      [PMID:] [10.1002/fft2.70146]

205. Qiye Xi, Xiaojing Lin, Yixian Xie, Fengyong Cheng, Ben Hu, Fengling Zhang, Fushan Sun, Bing Han, Yufang Lai, Yongxia Wang, Jigang Wang, Meng Yu.  (2025)  A sequential nanotherapy potentiate anti-angiogenic therapy by disrupting lipid metabolism under metabolic stress.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.170761]

206. Ting Liu, Zhuo Li, Yun Sun, Dan Chen.  (2025)  Stathmin 1 Attenuates the Myocardial Fibrosis in Rat Model of Heart Failure.  HUMAN GENE THERAPY,      [PMID:41212094] [10.1177/10430342251393698]

207. Yufang Guo, Longjie Li, Yongjun Wang, Zexu Wang, Wei Qiu, Qian Li, Li Wang, Bing Wan.  (2025)  The role of the MYL12A liquid-liquid phase separation in neutrophil improves the prognosis of acute respiratory distress syndrome: a multi-omics analysis.  Frontiers in Immunology,      [PMID:41235230] [10.3389/fimmu.2025.1662680]

208. Ji Li, Wenwen Zhang, Yue Zhang, Huanqiu Liu.  (2025)  ADAM8 Destroys the Endothelial Barrier and Promotes Leukocyte Extravasation to Aggravate Hepatic Ischemia–Reperfusion Injury.  FASEB JOURNAL,  39  (22): (e71217).  [PMID:41222986] [10.1096/fj.202500697R]

209. Zhang Haifeng, Su Tiantian, Wu Xiaoke, Shi Mengmeng.  (2025)  Microglial-Derived Cholesterol 25-Hydroxylase Promotes Epileptic Seizure and Neuroinflammation Mediated by NLRP3 Inflammasome and Lipid Metabolism.  Neuroscience Bulletin,      [PMID:41239156] [10.1007/s12264-025-01526-w]

210. Haotian Bai, Jing Yang, Junhao Zhang, Rui Wang.  (2025)  Self-Assembled Safflower Polysaccharide Nanoparticles as a Targeted Drug Delivery System for Enhanced Therapy of Hepatocellular Carcinoma.  International Journal of Nanomedicine,      [PMID:41216350] [10.2147/IJN.S544439]

211. Qian‐Kun Zhao, Yue‐Xin Ning, Tian‐Ce Xu, Zi‐Ai Zhao, Yi‐Feng Pei, Jing‐Yuan Niu, Xian‐Dong Li, Hui‐Sheng Chen.  (2025)  Electroacupuncture alleviate brain injury through vagus nerve activation and gut microbiota in a rat model of ischemic stroke.  Journal of the American Heart Association,      [PMID:41211649] [10.1161/JAHA.125.045929]

212. Jing Li, Meixue Chen, Lingling Lu, Yinmiao Wang, Wei Wu, Yanhong Feng.  (2025)  KLF Transcription Factor 5/Lysophosphatidic Acid Receptor 5 Induced M2 Macrophage Activation and Inflammation by Modulating Phosphorylation of Mitogen-Activated Protein Kinase Kinase Kinase 7 in Pediatric Asthma.  AMERICAN JOURNAL OF PATHOLOGY,  195  (12): (2320-2335).  [PMID:41276341] [10.1016/j.ajpath.2025.08.012]

213. Wang Ying, Liu Jiahui, Jiang Yiqun, Liu Yanzuo, Kuang Hongying, Feng Xiaoling.  (2025)  KLF5 drives granulosa cell apoptosis and inflammatory injury in polycystic ovary syndrome via transcriptional activation of TXNIP.  IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL,      [PMID:41269501] [10.1007/s11626-025-01124-0]

214. Xiaowei Yang, Guangduo Zhu, Ming Li, Haibo Zhan, Feng Wang.  (2025)  Deficiency of zinc finger protein 36 exacerbates sepsis-induced cardiomyopathy by activating ferroptosis.  EUROPEAN JOURNAL OF PHARMACOLOGY,      [PMID:41314455] [10.1016/j.ejphar.2025.178405]

215. Zeming Lei, Yansheng Wang, Liangzi Yin, Ziyuan Wang, Lunhao Bai.  (2025)  Periprosthetic osteolysis is mediated by the m6A-dependent regulation of CEMIP via YTHDF2.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:41308363] [10.1016/j.intimp.2025.115895]

216. He Dongjie, Ren Xingxing, Mao Jing, Shi Shaoqi, Song Yanli, Xiao Huidongzi, Wei Aiwu.  (2025)  Molecular mechanisms of ligustilide in the treatment of low endometrial receptivity: involvement of desmoglein-2.  MOLECULAR HUMAN REPRODUCTION,  31  (4):   [PMID:41208040] [10.1093/molehr/gaaf043]

217. Meng-Si Li, Kai Liu.  (2025)  Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF-κB Signaling.  KAOHSIUNG JOURNAL OF MEDICAL SCIENCES,      [PMID:41313694] [10.1002/kjm2.70144]

218. Xiaojun Zhang, Fang Wang, Yuna Dai, Zhaoyu Gao, Jianchao He.  (2025)  Polygalacin D Prevents Breast Cancer Progression through Proteasome-Mediated Degradation of HDAC1 and HDAC2.  BIOLOGICAL & PHARMACEUTICAL BULLETIN,  48  (12): (1897-1905).  [PMID:41371635] [10.1248/bpb.b25-00411]

219. Jiayi Xiao, Qi Li, Zhu Li, Lingxin Kong, Yang Shang, Yongliang Xu, Mo Dong, Sijin Zhang, Zitao Li, Caijuan Li.  (2025)  LAR1 activates NF-κB signaling pathway by binding to APOC1 mRNA and enhancing its expression: a novel mechanism underlying breast carcinogenesis.  iScience,      [PMID:41623496] [10.1016/j.isci.2025.114386]

220. Tian Tian, Luan Xiaona, Wang Lingzhi, Kong Yan, Huang Liying, Wang Yan.  (2025)  A novel function of STARD7: its tumor-promoting role involves the activation of NF-κB signaling pathway in ovarian cancer.  Human Cell,  39  (1): (20).  [PMID:41398485] [10.1007/s13577-025-01333-5]

221. Xiaoxu Ding, Hui Su, Tiancong Liu, Yu Chen, Zhao Gao, Ziwen Chang, Weiliang Bai.  (2025)  The GATA3-STEAP4 Axis Drives Inflammation by Promoting Th2 Differentiation in Allergic Rhinitis.  INFLAMMATION,  49  (1): (13).  [PMID:41422349] [10.1007/s10753-025-02381-7]

222. Yuling Zhang, Silue Zeng, Chuanyu Tang, Shuangqin He, Yingying Pan, Shuchang Li, Yaguang Ren, Mifang Li, Jianwei Tan, Min Zhang, Jingqin Chen, Chengbo Liu, Lingyan Zhang.  (2025)  A Sustainable ROS Cycle Generator (SRCG) for Tumor Chemodynamic Therapy.  Materials Today Bio,      [PMID:41551884] [10.1016/j.mtbio.2025.102709]

223. Pin Chen, Huan Cheng, Shiguo Chen, Xingqian Ye, Jianle Chen.  (2025)  Nitric oxide-responsive hyaluronic acid hydrogel microspheres enable anthocyanin protection and inflammation-triggered release.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41455548] [10.1016/j.ijbiomac.2025.149855]

224. Suwen Liu, Wenhong Jiang, Hanchen Li, Xuli Wang, Jiancheng Ma, Lina Dong.  (2025)  Lonicera caerulea Berry Polyphenols Regulate Cholesterol Metabolism in Rats With Type 2 Diabetes by Activating SIRT1 Expression in Macrophages and Reducing Foaming.  Food Frontiers,  7  (1): (e70204).  [PMID:] [10.1002/fft2.70204]

225. Kerong Yang, Xi Yue, Jinliang Wu, Guanhao Chen, Shumin Yang, Haojun Ma, Hongyu Tan.  (2026)  Accelerating bone healing in femoral defect model using FBXO6-modified bone marrow-derived mesenchymal stem cells on a collagen scaffold.  BIOCHEMICAL PHARMACOLOGY,      [PMID:41483826] [10.1016/j.bcp.2025.117669]

226. Xiang Jiakun, Shi Minghong, Kang Jiajia, Zhang Xingyuan, Ling Jiankai, Zhan Wei, Li Dianyi, Hu Rongfeng K., Xu Zhi-Xiang.  (2026)  Prefrontal cortex-to-hypothalamic outputs orchestrate cue-potentiated palatable food consumption via AMPKβ2 signaling.  Cell Discovery,  12  (1): (2).  [PMID:41495038] [10.1038/s41421-025-00857-2]

227. Changfu Zhang, Haichun Li, Yushuai Gao, Kaiyuan Deng, Rongjun Qian.  (2026)  Targeting the FBXW7-AKAP13-YAP axis suppresses gliomagenesis by dual inhibition of tumor invasion and macrophage recruitment.  BIOCHEMICAL PHARMACOLOGY,      [PMID:41506544] [10.1016/j.bcp.2026.117677]

228. Bo Pang, Yan Zhang, Yikai Bai, Siyuan Chen, Zhida Wang.  (2026)  ZBTB16 Improves Myelin Damage in Diabetic Peripheral Neuropathy by Inhibiting Schwann Cell Dedifferentiation.  FASEB JOURNAL,  40  (1): (e71412).  [PMID:41482827] [10.1096/fj.202502621RR]

229. Zenghui Hao, Jinbao Han, Ting Yao, Zheng Zhao, Wei Fan, Zaiqun Jiang, Yunting Wang, Xiaoqian Yang, Zhilin Xu.  (2026)  ALAS2 Prevents Neonatal Necrotizing Enterocolitis by Improving Ferroptosis in Intestinal Epithelial Cells Through Inhibition of Oxidative Stress.  MEDIATORS OF INFLAMMATION,      [PMID:41509986] [10.1155/mi/6683001]

230. Mao Huizi, Li Zhuqing, Lu Chengzhi.  (2026)  Protection against myocardial ischemia reperfusion injury by liquiritin: involvement of autophagy restoration targeting PIK3CA.  BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH,      [PMID:41538663] [10.1590/1414-431X2025e14964]

231. Mingxing Sui, Shuying Wu, Qingqing Song, Siyao Chen, Yingli Lu.  (2026)  Onecut2, negatively regulated by methyltransferase METTL3, inhibits polycystic ovary syndrome by transcriptionally modulating SIRT3 expression.  BIOCHEMICAL PHARMACOLOGY,      [PMID:41544857] [10.1016/j.bcp.2026.117712]

232. Fang Tong, Xue Gao, Yuhong Shang.  (2026)  USP18 promotes cell proliferation and inhibits ferroptosis by stabilizing HDAC3 in endometrial carcinoma.  EXPERIMENTAL CELL RESEARCH,      [PMID:41547495] [10.1016/j.yexcr.2026.114900]

233. Hu Xiwen, Sha Rui, Yang Feiran, Chai Jinwen, Liu Bin, Xu Xiaoqing.  (2026)  Chebulagic acid targets FBXO38 to enhance natural killer cell-mediated anti-tumor immunity in lung adenocarcinoma.  Human Cell,  39  (2): (36).  [PMID:41546764] [10.1007/s13577-026-01347-7]

234. Zexin Li, Xiao Wang, Yuanyuan Cui, Yi Liu, Rui Wei, Yixin Wang, Xiaolong Tang, Liangbin Li, Jiasai Li, Keqiang Zuo.  (2026)  Silencing OGFOD1 ameliorates hepatic ischemia–reperfusion injury through abrogating oxidative stress and apoptosis via downregulating SPARC.  BIOCHEMICAL PHARMACOLOGY,      [PMID:41558616] [10.1016/j.bcp.2026.117719]

235. Ma Shuainan, Liu Qi, Han Wei, Liu Zhiyi, Jin Sinan, Wu He, Hua Wei.  (2026)  UBA52 Overexpression Ameliorates Intracerebral Hemorrhage-Associated Neuronal Apoptosis and Mitochondrial Dysfunction: A Protective Role in Neurons.  MOLECULAR NEUROBIOLOGY,  63  (1): (371).  [PMID:41553582] [10.1007/s12035-025-05655-1]

236. Mao Dong, Sun Jufeng, Zhang Xiaowei, Wang Zhaoping, Zhang Yun.  (2026)  ILF2 cooperates with ILF3/KLF16 to drive colorectal cancer progression via modulating the behaviors of both tumor cells and M2 macrophages.  APOPTOSIS,  31  (2): (52).  [PMID:41572068] [10.1007/s10495-026-02259-5]

237. Ou Yuyang, Chen Chen, Wang Ziyi, Zhu Xi, Luo Yaoxing, Li Shulin, Li Dan.  (2026)  UBL4A as a suppressor of intracerebral hemorrhage by binding to MAPK14 and promoting MAPK14 ubiquitination.  Genes & Genomics,      [PMID:41575627] [10.1007/s13258-025-01723-x]

238. Lianjia Zhao, Xingang Li, Peiguo Wang, Weiwei Hao, Gan Li, Chunyan Li, Daolong Liao, Ke Wen.  (2026)  The transcription factor GmNAC018 confers salt tolerance in soybean.  Frontiers in Plant Science,      [PMID:41635685] [10.3389/fpls.2025.1728235]

239. Jingwen Zhang, Xin Jin, Yajiao Sun, Rongyao Xia, Fuhui Chen.  (2026)  Transcription factor TFAP2A drives EMT progress by activating BDKRB1 transcription: The potential mechanism by which TFAP2A promotes idiopathic pulmonary fibrosis.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:41587695] [10.1016/j.taap.2026.117736]

240. Qi Lou, Rui Bai, Luyifei Li, Bingqing Lu, Xiaoming Ai, Guangzhong Liu.  (2026)  Targeting ADAMTS4 aggravates myocardial ischemia-reperfusion injury by impairing endothelial integrity and accelerating leukocyte infiltration.  INTERNATIONAL JOURNAL OF CARDIOLOGY,      [PMID:41592699] [10.1016/j.ijcard.2026.134195]

241. Liwei Yang, Zhili Ge, Xuehan Ding, Jingjing Shi, Jiaxin Zhang, Tianyou Wang, Huibin Jiang, Xinyu Zhang, Liting Zhou.  (2026)  Tributyl phosphate disrupts hepatic lipid metabolism via cGAS-STING signal pathway mediated inflammation.  TOXICOLOGY LETTERS,      [PMID:41617062] [10.1016/j.toxlet.2026.111847]

242. Liwen Xu, Fei Zheng, Dandan Wang, Qing Yang.  (2026)  N-Alpha-Acetyltransferase 30, Transcriptionally Regulated by NR2C2, Promotes Ovarian Cancer Progression by Mediating ARPC1B Acetylation.  FASEB JOURNAL,  40  (3): (e71499).  [PMID:41615304] [10.1096/fj.202502867RR]

243. Meng Liu, Peng Jiang, Binghui Ruan, Yunfei Cui, Junjie Zhang, Yuxiu Ye, Dongting Zhangsun, Sulan Luo, Yong Wu.  (2026)  Rational β-turn engineering of a disulfide-free β-hairpin-like antimicrobial peptide W2PG with enhanced stability, selectivity, and in vivo efficacy.  BIOORGANIC CHEMISTRY,      [PMID:41690116] [10.1016/j.bioorg.2026.109612]

244. Guorui Song, Jinke Ji, Changying Li, Jinlong Zhao, Bo Zhang.  (2026)  A pMnO2@ABVN nanoparticle with dual pH/GSH response for the production of alkyl radicals for the treatment of osteosarcoma.  DALTON TRANSACTIONS,      [PMID:41648950] [10.1039/D5DT02532J]

245. Wei Min, Yang Jian, Yu Zejia, Li Shan, Xie Hui, Yuan Shiyang, Huang Qiujie, Zhang Hui, Feng Jun.  (2026)  Sorting nexin 10 knockdown: new strategies for alleviating sepsis-associated acute lung injury.  BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH,      [PMID:41711764] [10.1590/1414-431X2025e15117]

246. Man Gao, Xue Yang, Xiuxia Wang, Tong Liu.  (2026)  ZFP36 inhibits trophoblast ferroptosis and attenuates preeclampsia development by promoting NCOA4 mRNA degradation and suppressing ferritinophagy.  BIOCHEMICAL PHARMACOLOGY,      [PMID:41765113] [10.1016/j.bcp.2026.117836]

247. Yong Chen, Yanchao Zhang, Shen Rui, Bo Dong, Xiangshan Xu, Yuanzhe Jin.  (2026)  IRF6 induces endothelial dysfunction through the transcriptional activation of NDRG1 and aggravates low shear stress-mediated atherosclerosis.  iScience,  29  (3):   [PMID:41847611] [10.1016/j.isci.2026.115127]

248. Tao Yang, Tao Wang, Tao Shen, Mingrong Dong, Jinkun Liu, Ming Ni, Yan Zhu.  (2026)  Tumor Microenvironment-Responsive Nanoplatform of Cu-Doped ZIF-8 Dual-Loaded with ICG and DOX for Photothermal-Enhanced Chemodynamic Therapy/Chemotherapy.  ACS Omega,      [PMID:41768684] [10.1021/acsomega.5c11491]

249. Huanhuan Wang, Hanshu Zhao, Jiadi Gao, Sihan Liu, Yuanqi Xu, Xinyue Zhao, Shanshan Yang, Baozhi Gang, Zhongling Zhang.  (2026)  METTL14/m6A/CEBPD Axis: A Critical Player in Chronic Cerebral Hypoperfusion–Associated Neuroinflammation.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:41791683] [10.1016/j.freeradbiomed.2026.03.013]

250. Bo Pang, Siyuan Chen, Yikai Bai, Yan Zhang, Zhida Wang.  (2026)  NR4A3 alleviates diabetic neuropathy via GLS2-mediated mitochondrial repair and Schwann cell differentiation.  iScience,      [PMID:] [10.1016/j.isci.2026.115515]

251. Han Tianci, Xie Junwei, Tong Wei, Zhang Liang.  (2026)  ID4 suppresses proliferation and macrophage polarization in esophageal carcinoma through interaction with TCF4.  MOLECULAR CANCER RESEARCH,      [PMID:41770101] [10.1158/1541-7786.MCR-25-0686]

252. Ren Niansheng, Li Ruixi, Tao Qiang, Hong Shengjie, Wang Jicai, Zha Jiandong, Wang Shikai, Zhang Guangquan.  (2026)  Nicotinamide N-Methyltransferase Inhibition Mitigates Cerulein-Induced Pancreatic Fibrosis via Galectin-3-Mediated Regulation of Stellate Cell Activation and Macrophage M2 Polarization in Mice.  INFLAMMATION,      [PMID:] [10.1007/s10753-026-02491-w]

253. Bingyu Chen, Ke Liu, Yaya Guo, Jingwei Zhao, Yanhua Wang.  (2026)  Epi-Berberine Alleviates Ulcerative Colitis, Protects the Intestinal Mucosal Barrier, and Inhibits Colonic Inflammation via Glutaminyl-Peptide Cyclotransferase in a Mouse Model of DSS-Induced Colitis.  PHYTOTHERAPY RESEARCH,      [PMID:] [10.1002/ptr.70300]

254. Yang Di, Liu Jia, Gao Yan, Guan Xin, Tong Rui.  (2026)  RNF125 promotes CD8 T cell-mediated anticancer immunity and suppresses the malignant phenotype of cervical cancer.  MOLECULAR AND CELLULAR BIOCHEMISTRY,      [PMID:] [10.1007/s11010-026-05507-z]

255. Wang Dongyan, Shi Yihai, Lu Jie, Bao Wen, Wang Nan, Shen Qiuteng, Lin Zhenyu, Qian Lijuan, Zhu Chang.  (2026)  A Novel Insight into Chronic Pancreatitis Pathogenesis: the USP1/ITGB5 Axis-Mediated Stellate Cell Activation.  INFLAMMATION,      [PMID:41857463] [10.1007/s10753-025-02434-x]

256. Meng Hui, Wang Zeyuan, Wang Liye, Fang Xiaokun, Li Haonan, Ma Weiqian, Ding Yi, Nan Manman, Meng Yu, Li Ling, Li Yizhen, Chen Kuisheng, Zhang Mingzhi.  (2026)  ZG16 represses tumor progression and M2 polarization of tumor-associated macrophages in hepatocellular carcinoma by promoting ubiquitination and degradation of SNX9 via binding to ITCH.  Hepatology International,      [PMID:41781795] [10.1007/s12072-026-11067-7]

257. Dan Wang, Liran Xu, Yangang Sun, Jingyu Yue, Liangping Li.  (2026)  SERPINE1 Drives Neuropathic Pain in a Resiniferatoxin-Induced Model via AKT-Mediated Neuronal Apoptosis.  BRAIN RESEARCH BULLETIN,      [PMID:41806904] [10.1016/j.brainresbull.2026.111820]

258. Jingjing Li, Xiaoxia Feng, Ranran Si, Yuanyuan Liu, Zhifang Huo, Huanqing Song, Chuan Zhou.  (2026)  SFRP2 is involved in hyperoxia-induced bronchopulmonary dysplasia in newborn mice by suppressing Nrf2/HO-1 pathway.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH,      [PMID:] [10.1016/j.bbamcr.2026.120157]