Technical articles

Aladdin®Ligands of Immunopharmacology



Product Manager:Harrison Michael


Introduction

At the forefront of life sciences and biomedical research, immunopharmacological ligands, as key tools, are leading new breakthroughs and discoveries. Immune ligands are small molecules, antibodies, and cytokines that can precisely bind to important receptors, cytokines, and signaling pathways in the immune system. They promote the advancement of immunopharmacology by regulating immune responses, studying mechanisms of inflammation, and exploring autoimmune diseases.

 

The application of immunopharmacological ligands spans all stages from basic research to clinical applications. Researchers use these ligands to deeply analyze the activation process of immune cells, reveal the signaling pathways of cytokines, and explore immune regulatory mechanisms. This not only helps us better understand the human immune system but also provides valuable clues for the development of innovative immune therapies.

 

Aladdin Scientific, in the field of immunopharmacological ligands, provides strong support for scientists with its rich product variety and high-quality R&D level. Our immune ligand products cover targets of various immune receptors, cytokines, and signaling pathways, allowing researchers to choose the right tools to meet their research needs. Whether exploring the basic mechanisms of the immune system or developing new therapeutic methods, our products aim to be a reliable partner on your scientific journey.


Activator

Cat.No

Product Name

CAS

Research Category

Size

N304300

N,N-Dimethylimidodicarbonimidic diamide (AMPK activator)

657-24-9

Metabolism

250mg;1g;5g;25g

M333473

ML 265 (PKM1/2 activator)

1221186-53-3

Metabolism

5mg;10mg;25mg;50mg;100mg

G122413

Gabapentin (Kv7.3 activator)

60142-96-3

Ion channel

5g;25g;100g;500g

S413831

SRT2104 (GSK2245840) (SIRT1 activator)

1093403-33-8

Cell cycle

5mg;25mg;100mg

O413808

Omaveloxolone (RTA-408) 
(NRF2 activator)

1474034-05-3

REDOX

2mg;5mg;10mg;25mg;

50mg;100mg

 

Agonist

Cat.No

Product Name

CAS

Research Category

Size

O412242

6-OAU (GPR84 full agonist)

83797-69-7

G protein-coupled receptors

5mg;25mg;100mg

B276435

BMS202 (PD-1/PD-L1 inhibitor 2) 
(CB
1 receptor agonist)

1675203-84-5

G protein-coupled receptors

1mg;5mg;10mg;

25mg;50mg;100mg

B129690

BRL-15572 
(5-HT
1A receptor partial agonist)

193611-72-2

G protein-coupled receptors

1mg;5mg;10mg;50mg

E113174

L-Adrenaline 
(Alpha-1A adrenoceptor full agonist)

51-43-4

G protein-coupled receptors

1g;5g;25g

P177659

Ponesimod (S1P1 receptor agonist)

854107-55-4

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

S287264

SCH 336 (CB1 receptor inverse agonist)

447459-51-0

G protein-coupled receptors

10mg;25mg;50mg

O413886

Ozanimod (RPC1063) 
(S1P1 receptor agonist)

1306760-87-1

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

O356683

Olodaterol (ADRB2 agonist)

868049-49-4

G protein-coupled receptors

5mg;10mg;25mg;100mg

V125545

Vortioxetine 
(5-HT1A receptor partial agonist)

508233-74-7

G protein-coupled receptors

10mg;50mg;250mg;1g

S346847

Salmeterol (ADRB2 full agonist)

89365-50-4

G protein-coupled receptors

5mg;10mg;25mg;50mg;
100mg;250mg;500mg;1g

B136672

Brimonidine (ADRA2A full agonist)

59803-98-4

G protein-coupled receptors

250mg;1g;5g

I125935

Indacaterol (ADRB1 agonist)

312753-06-3

G protein-coupled receptors

10mg;50mg;250mg

T413890

TIC10 (ONC201) (IGF-1R agonist)

1616632-77-9

Protein tyrosine kinase

5mg;10mg;50mg;

100mg;200mg

C413868

2',3'-cGAMP Sodium Salt 
(stimulator of interferon response cGAMP interactor 1 agonist)

1441190-66-4

Immunity and inflammation

1mg;5mg;10mg

M413715

Motolimod (VTX-2337) (TLR8 agonist)

926927-61-9

Immunity and inflammation

1mg;5mg;25mg

T414465

Tapinarof 
(Aryl hydrocarbon receptor agonist)

79338-84-4

Immunity and inflammation

25mg;100mg;250mg;1g

M337171

6α-Methyl-11β-hydroxyprogesterone (Glucocorticoid receptor agonist)

2668-66-8

Endocrinology and hormones

25mg;100mg;250mg

B129370

Beclomethasone dipropionate 
(GR agonist)

1327543

Endocrinology and hormones

250mg;1g;5g;25g

D336852

Desoximetasone 
(Glucocorticoid receptor agonist)

382-67-2

Endocrinology and hormones

50mg;100mg;250mg;1g

D129585

Deflazacort (GR agonist)

14484-47-0

Endocrinology and hormones

1g;5g

D129996

Desonide (GR agonist)

638-94-8

Endocrinology and hormones

250mg;1g;5g;25g

B129941

Budesonide 
(Glucocorticoid receptor agonist)

51333-22-3

Endocrinology and hormones

50mg;100mg;250mg;1g;5g

P116562

Prednisone (GR agonist)

19420

Endocrinology and hormones

1g;5g;25g

T101294

Triamcinolone acetonide 
(Glucocorticoid receptor agonist)

76-25-5

Endocrinology and hormones

250mg;1g;5g;25g

F138831

Fluorometholone 
(Glucocorticoid receptor agonist)

426-13-1

Endocrinology and hormones

250mg;1g;5g

F129893

Fluocinonide 
(Glucocorticoid receptor agonist)

356-12-7

Endocrinology and hormones

25mg;100mg;250mg;500mg

H110523

Hydrocortisone 
(Glucocorticoid receptor agonist)

50-23-7

Endocrinology and hormones

1g;5g;25g;100g

C287438

Ciclesonide 
(Glucocorticoid receptor agonist)

126544-47-6

Endocrinology and hormones

5mg;25mg;100mg;500mg

F413479

fluticasone furoate (GR agonist)

397864-44-7

Endocrinology and hormones

25mg;50mg;100mg;

250mg;1g;5g

M333017

Mometasone 
(Glucocorticoid receptor agonist)

105102-22-5

Endocrinology and hormones

5mg;25mg;50mg;100mg

F129244

Fluocinolone Acetonide 
(Glucocorticoid receptor agonist)

67-73-2

Endocrinology and hormones

250mg;1g;5g;25g

S414287

SX-682

(TRAIL agonist)

1648843-04-2

Apoptosis

5mg;10mg;25mg;50mg;100mg

F305092

Fingolimod (KCa3.4 agonist)

162359-55-9

Ion channel

50mg;250mg;1g;5g


Allosteric Modulator

Cat.No

Product Name

CAS

Research Category

Size

A286695

AZ 3451

(PAR2 inhibitor)

2100284-59-9

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

R126706

Reparixin

(CXCR2 inhibitor)

266359-83-5

G protein-coupled receptors

1mg;5mg;25mg;100mg

B126876

BMS-345541 (IKK inhibitor)

547757-23-3

NF-κB signaling pathway

5mg;10mg;25mg;50mg;100mg

 

Antagonist

Cat.No

Product Name

CAS

Research Category

Size

A275394

AH 6809 (DP1 receptor antagonist)

33458-93-4

G protein-coupled receptors

10mg;50mg;100mg

A286753

AMG 853 (DP1 receptor antagonist)

1169483-24-2

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

A288638

AZD 2098 (CCR4 antagonist)

566203-88-1

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

A129498

AZD1981 (DP2 receptor antagonist)

802904-66-1

G protein-coupled receptors

5mg;25mg

A413565

AZD5069 (CXCR1 antagonist)

878385-84-3

G protein-coupled receptors

5mg;10mg;25mg;
50mg;100mg;200mg

A412409

Avacopan (CCX168) (C5a1 receptor antagonist)

1346623-17-3

G protein-coupled receptors

5mg;10mg;25mg;50mg

B286564

BX 471 (CCR1 antagonist)

217645-70-0

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

C413566

Ciforadenant (CPI-444) 
(Adenosine A2A receptor antagonist)

1202402-40-1

G protein-coupled receptors

5mg;25mg;100mg

G287679

GLPG 0974 (FFA2 receptor antagonist)

1391076-61-1

G protein-coupled receptors

1mg;5mg;10mg;25mg

G286917

GSK 2239633A (CCR4 antagonist)

1240516-71-5

G protein-coupled receptors

1mg;5mg;10mg;25mg;50mg;

G288949

GW 627368 (EP4 receptor antagonist)

439288-66-1

G protein-coupled receptors

1mg;5mg;10mg;25mg;50mg;250mg

L275852

LY255283 (BLT1 receptor antagonist)

117690-79-6

G protein-coupled receptors

1mg;5mg;10mg;25mg;50mg;100mg

N413659

NE 52-QQ57 (GPR4 antagonist)

1401728-56-0

G protein-coupled receptors

2mg;5mg;10mg;25mg;50mg;100mg

N414035

Navarixin (SCH-527123) 
(CXCR1 antagonist)

473727-83-2

G protein-coupled receptors

5mg;25mg;100mg

O125509

ONO-AE3-208 (EP3 receptor antagonist)

402473-54-5

G protein-coupled receptors

5mg;10mg;25mg;50mg

P286546

PF 04418948 (EP2 receptor antagonist)

1078166-57-0

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

R340645

RE 201 (AT1 receptor antagonist)

254740-64-2

G protein-coupled receptors

25mg;50mg;100mg;250mg

R335959

RS 102895 (CCR2 antagonist)

300815-41-2

G protein-coupled receptors

1mg;5mg;10mg;25mg;50mg;100mg

R169388

RS504393 (CCR2 antagonist)

300816-15-3

G protein-coupled receptors

5mg;25mg

S275393

SB 225002 (CXCR2 antagonist)

182498-32-4

G protein-coupled receptors

5mg;10mg;50mg;100mg

S274805

SB 328437 (CCR3 antagonist)

247580-43-4

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

S413325

Setipiprant (ACT-129968) 
(DP
2 receptor antagonist)

866460-33-5

G protein-coupled receptors

25mg;100mg

M413330

Montelukast (CysLT1 receptor antagonist)

158966-92-8

G protein-coupled receptors

100mg;250mg;1g;5g

P126767

Preladenant 
(Adenosine A1 receptor antagonist)

377727-87-2

G protein-coupled receptors

5mg;10mg;25mg;50mg;100mg

V127296

Verlukast (CysLT1 receptor antagonist)

120443-16-5

G protein-coupled receptors

5mg;25mg

M118674

Melatonin (5-HT2B receptor antagonist)

73-31-4

G protein-coupled receptors

5g;25g;100g;500g

C176619

cenicriviroc (CCR5 antagonist)

497223-25-3

G protein-coupled receptors

1mg;5mg;25mg;100mg

D178502

danirixin (CXCR2 antagonist)

954126-98-8

G protein-coupled receptors

1mg;5mg;10mg;25mg;50mg;

F339243

Fexofenadine (H1 receptor antagonist)

83799-24-0

G protein-coupled receptors

250mg;1g;5g;25g

M125486

Maraviroc (CCR5 antagonist)

376348-65-1

G protein-coupled receptors

5mg;25mg;100mg

S413619

S1RA (SIGMAR1 antagonist)

878141-96-9

Ion channel

5mg;10mg;25mg;
50mg;100mg;250mg

G413575

Gefapixant (P2X3 antagonist)

1015787-98-0

Ion channel

5mg;10mg;25mg;50mg;100mg

H287635

H 151 (STING antagonist)

941987-60-6

Immunity and inflammation

5mg;10mg;50mg;100mg;250mg

T125887

TAK-242 (TLR4 antagonist)

243984-11-4

Immunity and inflammation

1mg;5mg;10mg;50mg;100mg

Y287609

YM 90709 (IL5R antagonist)

163769-88-8

Immunity and inflammation

2mg;10mg;50mg;250mg

A124869

ABT-199 (GDC-0199) 
(Bcl-2-like 1 antagonist)

1257044-40-8

Apoptosis

5mg;10mg;25mg;
50mg;100mg;500mg

L171714

Lifitegrast (integrin, alpha L subunit (CD11A) antagonist)

1025967-78-5

Cytoskeleton

25mg;100mg;250mg;1g


Channel Blocker

Cat.No

Product Name

CAS

Research Category

Size

Y276423

YM-58483 (BTP2) 
(TRPC3 antagonist)

223499-30-7

Ion channel

1mg;5mg;10mg;

25mg;50mg;100mg

N288469

NS 6180 (KCa3.1 inhibitor)

353262-04-1

Ion channel

10mg;50mg;250mg

F336824

Forsythoside B (TRPV3 inhibitor)

81525-13-5

Ion channel

5mg;25mg;50mg;100mg

D155733

Diclofenac (ASIC3 relevant agents)

15307-86-5

Ion channel

1g;5g;25g;100g;500g

A118582

Acetylsalicylic acid 
(ASIC3 relevant agents)

50-78-2

Ion channel

250g;1kg

I275380

Iberiotoxin (KCa1.1 relevant agents)

129203-60-7

Ion channel

1mg

F129495

2-(3-Trifluoromethylanilino)benzoic Acid 
(CaCC relevant agents)

530-78-9

Ion channel

5g;25g;100g

S104158

Salicylic acid (ASIC3 relevant agents)

69-72-7

Ion channel

100g;250g;500g;

1kg;2.5kg;5kg

 

Inhibitor

Cat.No

Product Name

CAS

Research Category

Size

T288613

TH 5487 (OGG1 inhibitor)

2304947-71-3

DNA damage and repair

25mg;50mg;100mg

P125128

PJ34 (PARP1 inhibitor)

344458-19-1

DNA damage and repair

5mg;10mg;25mg;
50mg;100mg;250mg

C107672

Celastrol (RGS17 inhibitor)

34157-83-0

G protein-coupled receptors

10mg;50mg

R341807

(R)-Lisofylline (STAT4  inhibitor)

100324-81-0

JAK/STAT signaling pathway

2mg;5mg;10mg;25mg;50mg

A414165

Abrocitinib (PF-04965842) 
(JAK1 inhibitor)

1622902-68-4

JAK/STAT signaling pathway

5mg;10mg;25mg;50mg;100mg

D413775

Decernotinib (VX-509) (JAK1 inhibitor)

944842-54-0

JAK/STAT signaling pathway

2mg;5mg;10mg;25mg;50mg;100mg

P414192

PF-06700841 (JAK1 inhibitor)

1883299-62-4

JAK/STAT signaling pathway

5mg;10mg;25mg;50mg;100mg

U302354

Upadacitinib (JAK1 inhibitor)

1310726-60-3

JAK/STAT signaling pathway

50mg;100mg;250mg;500mg

I413838

Itacitinib (INCB39110) (JAK1 inhibitor)

1334298-90-6

JAK/STAT signaling pathway

5mg;10mg;25mg;
50mg;100mg;250mg

R414045

Ritlecitinib (PF-06651600) (JAK1 inhibitor)

1792180-81-4

JAK/STAT signaling pathway

5mg;10mg;25mg;50mg;100mg

T122330

Tofacitinib (JAK1 inhibitor)

477600-75-2

JAK/STAT signaling pathway

5mg;25mg;100mg;500mg;1g

S413366

Solcitinib (JAK1 inhibitor)

1206163-45-2

JAK/STAT signaling pathway

5mg;25mg

S129613

S-Ruxolitinib (INCB018424) 
(JAK1 inhibitor)

941685-37-6

JAK/STAT signaling pathway

1mg;5mg;10mg;25mg;50mg;100mg

B413913

BMS-582949 (MAPK14 inhibitor)

623152-17-0

MAPK signaling pathway

1mg;5mg;25mg;50mg;100mg

C126262

CC-930 (MAPK10 inhibitor)

899805-25-5

MAPK signaling pathway

5mg;10mg;25mg;50mg;100mg

L333143

Losmapimod (MAPK14 inhibitor)

585543-15-3

MAPK signaling pathway

5mg;10mg;25mg;
50mg;100mg;250mg

M412289

MW-150 (MAPK14 inhibitor)

1628502-91-9

MAPK signaling pathway

1mg;5mg;10mg;25mg;50mg;100mg

P127738

PH-797804 (MAP3K11 inhibitor)

586379-66-0

MAPK signaling pathway

5mg;10mg;25mg;100mg

S134307

SB 202190 (MAPK14 inhibitor)

152121-30-7

MAPK signaling pathway

5mg;25mg;100mg

S413964

Selonsertib (GS-4997) (MAP3K5 inhibitor)

1448428-04-3

MAPK signaling pathway

5mg;25mg;100mg;500mg

T125460

TAK-715 (MAPK11 inhibitor)

303162-79-0

MAPK signaling pathway

1mg;5mg;25mg;100mg

T287056

TCS JNK 5a (MAPK10 inhibitor)

312917-14-9

MAPK signaling pathway

5mg;10mg;25mg;
50mg;100mg;250mg

V126681

VX-745 (MAPK 11 inhibitor)

209410-46-8

MAPK signaling pathway

10mg;25mg;50mg;100mg;250mg

P413914

Pamapimod (MAPK10 inhibitor)

449811-01-2

MAPK signaling pathway

1mg;5mg;10mg;
50mg;100mg;250mg

V127521

Vemurafenib (PLX4032, RG7204) 
(BRAF inhibitor)

918504-65-1

MAPK signaling pathway

10mg;25mg;50mg;
100mg;500mg;1g;5g

S125267

SP600125 (MAPK10 inhibitor)

129-56-6

MAPK signaling pathway

25mg;50mg;100mg;

500mg;1g;5g

B338598

Bentamapimod 
(JNK competitive inhibitor)

848344-36-5

MAPK signaling pathway

5mg;10mg;50mg;100mg

D125100

Doramapimod (MAPK11 inhibitor)

285983-48-4

MAPK signaling pathway

10mg;50mg;250mg

G414233

GSK8612 (IKBKE inhibitor)

2361659-62-1

NF-κB signaling pathway

2mg;5mg;10mg;25mg;50mg;100mg

M127370

MLN120B (IKBKB inhibitor)

783348-36-7

NF-κB signaling pathway

5mg;10mg;25mg;50mg;100mg

M126461

MRT67307 (IKBKE inhibitor)

1190378-57-4

NF-κB signaling pathway

5mg;10mg;25mg;50mg;100mg

A136009

Amlexanox (IKBKE inhibitor)

68302-57-8

NF-κB signaling pathway

250mg;1g;5g

A413839

AMG319 (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha inhibitor)

1608125-21-8

PI3K/Akt/mTOR 
signaling pathways

5mg;10mg;25mg;50mg;100mg

A129503

AS-252424 (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha inhibitor)

900515-16-4

PI3K/Akt/mTOR 
signaling pathways

1mg;2mg;5mg;25mg;100mg

C127044

CAL-101 (PIK3CA inhibitor)

870281-82-6

PI3K/Akt/mTOR 
signaling pathways

10mg;50mg;100mg;250mg;500mg

I126464

Duvelisib (IPI-145, INK1197) 
(PIK3CA inhibitor)

1201438-56-3

PI3K/Akt/mTOR 
signaling pathways

5mg;10mg;25mg;50mg;100mg;1g

E413975

Eganelisib (IPI-549) (PIK3CA inhibitor)

1693758-51-8

PI3K/Akt/mTOR 
signaling pathways

5mg;25mg;100mg

G127233

GSK2126458 (GSK458) (mTOR inhibitor)

1086062-66-9

PI3K/Akt/mTOR 
signaling pathways

2mg;5mg;10mg;25mg;50mg;100mg

G413879

GSK2292767 (PIK3CD inhibitor)

1254036-66-2

PI3K/Akt/mTOR 
signaling pathways

1mg;5mg;10mg;25mg;50mg;

S414058

Seletalisib (UCB-5857) (PIK3CA inhibitor)

1362850-20-1

PI3K/Akt/mTOR 
signaling pathways

2mg;5mg;25mg;50mg

T414107

Tenalisib (RP6530) (PIK3CA inhibitor)

1639417-53-0

PI3K/Akt/mTOR 
signaling pathways

1mg;5mg;10mg;

25mg;50mg;100mg

L414153

leniolisib (CDZ 173) (PIK3CA inhibitor)

1354690-24-6

PI3K/Akt/mTOR 
signaling pathways

1mg;5mg;10mg;

25mg;50mg;100mg

E125341

Everolimus (mTOR inhibitor)

159351-69-6

PI3K/Akt/mTOR 
signaling pathways

5mg;25mg;100mg;500mg

N130417

Miltefosine (AKT1 inhibitor)

58066-85-6

PI3K/Akt/mTOR 
signaling pathways

100mg;500mg;1g;5g;25g

C274682

C646 (E1A binding agent protein p300 inhibitor)

328968-36-1

Epigenetics

1mg;5mg;25mg;

100mg;250mg;1g

H331683

CAY10603 (HDAC1 inhibitor)

1045792-66-2

Epigenetics

1mg;5mg;10mg;25mg;100mg

C419831

CC-885 (HDAC inhibitor)

1010100-07-8

Epigenetics

5mg;10mg;25mg;50mg;100mg

G275049

GSK-J1 (KDM5A inhibitor)

1373422-53-7

Epigenetics

10mg;25mg;50mg;100mg

G276086

GSK-J4 (KDM5B inhibitor)

1373423-53-0

Epigenetics

5mg;10mg;25mg;50mg;100mg

I166771

I-BET762 (BRD2 inhibitor)

1260907-17-2

Epigenetics

5mg;10mg;25mg;
50mg;100mg;250mg

M166588

ML324 (KDM4A inhibitor)

1222800-79-4

Epigenetics

5mg;10mg;25mg;50mg;100mg

S357869

SGC-CBP30 (CBP inhibitor)

1613695-14-9

Epigenetics

5mg;10mg;25mg;50mg;100mg

T413903

Tubastatin A (HDAC1 inhibitor)

1252003-15-8

Epigenetics

25mg;50mg;100mg;250mg

D413446

Diroximel Fumarate (HDAC inhibitor)

1577222-14-0

Epigenetics

5mg;10mg;25mg;50mg;100mg

M192391

1-Methyl-5-p-toluoylpyrrole-2-acetic acid (HDAC inhibitor)

26171-23-3

Epigenetics

250mg;1g;5g;25g

C106740

Colchicine (BRD4 inhibitor)

64-86-8

Epigenetics

500mg;1g;5g

N129302

Nabumetone (HDAC inhibitor)

42924-53-8

Epigenetics

250mg;1g;5g;25g

C124965

Cilomilast (HDAC inhibitor)

153259-65-5

Epigenetics

1mg;5mg;10mg;50mg;100mg

A405692

Alcaftadine (HDAC inhibitor)

147084-10-4

Epigenetics

25mg;100mg;500mg

C126527

CUDC-907 (HDAC1 inhibitor)

1339928-25-4

Epigenetics

1mg;5mg;10mg;

25mg;50mg;100mg

A413743

AZD3965 (MCT1 inhibitor)

1448671-31-5

Metabolism

1mg;5mg;10mg;

25mg;50mg;100mg

F340883

FIPI (PLD1 inhibitor)

939055-18-2

Metabolism

1mg;5mg;10mg;

25mg;50mg;100mg

P170364

PFK15 (PFKFB3 inhibitor)

4382-63-2

Metabolism

5mg;25mg;100mg

T129937

Teriflunomide (DHODH inhibitor)

108605-62-5

Metabolism

25mg;100mg;250mg;1g;5g

V413727

Vidofludimus (DHODH inhibitor)

717824-30-1

Metabolism

5mg;25mg;50mg;100mg

Z414252

Ziritaxestat (GLPG1690) 
(autotaxin inhibitor)

1628260-79-6

Metabolism

5mg;10mg;25mg;50mg;100mg

D107664

7-(2,3-Dihydroxypropyl)theophylline 
(PDE inhibitor)

479-18-5

Metabolism

5g;25g;100g;500g;2.5kg

E129317

Etodolac (COX-2 inhibitor)

41340-25-4

Metabolism

200mg;1g;5g;25g;100g

E126660

Etoricoxib (COX-2 inhibitor)

202409-33-4

Metabolism

10mg;50mg;250mg;1g;5g

C153919

Carprofen (COX-2 inhibitor)

53716-49-7

Metabolism

1g;5g;25g;100g

C413025

Cerdulatinib (AMP kinase inhibitor)

1198300-79-6

Metabolism

10mg;25mg;50mg;

100mg;200mg

O129871

Ozagrel (CYP5A1 inhibitor)

82571-53-7

Metabolism

10mg;50mg;250mg;1g;5g

T137617

Terfenadine (CYP2J2 inhibitor)

50679-08-8

Metabolism

1g;5g

L129349

Lumiracoxib (COX-2 inhibitor)

220991-20-8

Metabolism

10mg;50mg;100mg;

250mg;1g

D125951

Darapladib (PLA2-G7 inhibitor)

356057-34-6

Metabolism

5mg;10mg;50mg

K194835

Ketorolac (COX-1 inhibitor)

74103-06-3

Metabolism

250mg;1g;5g;25g

A126902

Apremilast (PDE4A inhibitor)

608141-41-9

Metabolism

25mg;250mg;1g;5g;25g

Z128028

Zileuton (5-LOX inhibitor)

111406-87-2

Metabolism

10mg;50mg;250mg;1g;5g

B129927

Bindarit (FABP4 inhibitor)

130641-38-2

Metabolism

5mg;10mg;50mg

D127353

DMAT (Casein kinase 2 inhibitor)

749234-11-5

Protein tyrosine kinase

10mg;50mg;250mg

A413911

Acalabrutinib (ACP-196) (BLK proto-oncogene, Src family tyrosine kinase inhibitor)

1420477-60-6

Protein tyrosine kinase

25mg;50mg;100mg;250mg;1g

D126373

DCC-2036 (Rebastinib) (ABL1 inhibitor)

1020172-07-9

Protein tyrosine kinase

5mg;10mg;50mg

B129232

Bafetinib (INNO-406) (ABL1 inhibitor)

859212-16-1

Protein tyrosine kinase

5mg;10mg;25mg;50mg;100mg

L127298

LY2801653 
(AXL receptor tyrosine kinase inhibitor)

1206799-15-6

Protein tyrosine kinase

5mg;10mg;25mg;50mg;100mg

P414234

PLX5622 (KIT inhibitor)

1303420-67-8

Protein tyrosine kinase

5mg;25mg;50mg;

100mg;250mg

S125985

Sotrastaurin (PRKCA inhibitor)

425637-18-9

Protein tyrosine kinase

1mg;5mg;25mg;100mg

W288403

WH-4-023 (LCK inhibitor)

837422-57-8

Protein tyrosine kinase

5mg;10mg;25mg;50mg;100mg

I124963

Imatinib (STI571) (ABL1 inhibitor)

152459-95-5

Protein tyrosine kinase

1g;5g;25g;100g

P127143

Ibrutinib (PCI-32765) (BLK inhibitor)

936563-96-1

Protein tyrosine kinase

10mg;50mg;250mg;1g;5g;25g

P127550

Ponatinib (AP24534) (ABL1 inhibitor)

943319-70-8

Protein tyrosine kinase

10mg;50mg;250mg

D125110

Dasatinib (ABL1 inhibitor)

302962-49-8

Protein tyrosine kinase

25mg;100mg;500mg;

1g;5g;25g

A414052

Avapritinib (BLU-285) (KIT inhibitor)

1703793-34-3

Protein tyrosine kinase

1mg;2mg;5mg;10mg;
25mg;50mg;100mg;250mg

M126981

Masitinib (AB1010) (KIT inhibitor)

790299-79-5

Protein tyrosine kinase

25mg;100mg;500mg

O127572

ONX-0914 (PR-957) (PSMB8 inhibitor)

960374-59-8

Proteasome

5mg;10mg;25mg;50mg;100mg

N413878

Nemiralisib (GSK2269557) 
(K
v11.1 inhibitor)

1254036-71-9

Ion channel

5mg;10mg;25mg;50mg;100mg

T126856

Thalidomide (TNF-α inhibitor)

50-35-1

Immunity and inflammation

250mg;1g;5g;25g;100g

D286906

3-(Methylsulfonyl)propanenitrile 
(NLRP3 inhibitor)

54863-37-5

Immunity and inflammation

10mg;50mg;250mg;1g

B305029

BLZ945 (CSF1R inhibitor)

953769-46-5

Immunity and inflammation

5mg;25mg;100mg

C413725

CNX-774 (BTK inhibitor)

1202759-32-7

Immunity and inflammation

5mg;10mg;50mg

C413116

CU-CPT-8m (TLR8 inhibitor)

125079-83-6

Immunity and inflammation

5mg;10mg;25mg;50mg

C288007

CY 09 (NLRP3 inhibitor)

1073612-91-5

Immunity and inflammation

10mg;50mg;250mg

E414483

Emavusertib (CA-4948) (IRAK4 inhibitor)

1801344-14-8

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

E413870

Epacadostat (INCB024360) 
(IDO1 inhibitor)

1204669-58-8

Immunity and inflammation

5mg;10mg;25mg;50mg;
100mg;250mg;500mg;1g

E414173

Evobrutinib (M-2951) (BTK inhibitor)

1415823-73-2

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

I288743

IRAK1/4 Inhibitor I (IRAK1 inhibitor)

509093-47-4

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

L275321

LFM-A13 (BTK inhibitor)

244240-24-2

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

L414473

Lanraplenib (GS-9876) (SYK inhibitor)

1800046-95-0

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

L414088

Linrodostat (BMS-986205) 
(indoleamine 2,3-dioxygenase 1 inhibitor)

1923833-60-6

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

M414276

MCC950 (NLRP3 inhibitor)

210826-40-7

Immunity and inflammation

2mg;5mg;10mg;50mg;100mg

M129713

ML130 (Nodinitib-1) (NOD1 inhibitor)

799264-47-4

Immunity and inflammation

5mg;25mg;100mg

M412317

MPO-IN-28 (MPO inhibitor)

37836-90-1

Immunity and inflammation

5mg;25mg;100mg;250mg

P413567

PF-06282999 (MPO inhibitor)

1435467-37-0

Immunity and inflammation

5mg;25mg;50mg;100mg

P175464

PF-06840003 (IDO1 inhibitor)

198474-05-4

Immunity and inflammation

5mg;10mg;25mg;
50mg;100mg;250mg

P420009

PF-06928215 (cGAS inhibitor)

2378173-15-8

Immunity and inflammation

1mg;5mg;10mg;25mg;50mg;100mg

P168059

PF06650833 (IRAK4 inhibitor)

1817626-54-2

Immunity and inflammation

5mg;25mg;100mg

R414448

Remibrutinib (LOU064) 
(Bruton tyrosine kinase inhibitor)

1787294-07-8

Immunity and inflammation

5mg;25mg;100mg

S413718

Setanaxib (GKT137831) (CYBB inhibitor)

1218942-37-0

Immunity and inflammation

5mg;25mg;100mg;250mg;1g

V412124

Verdiperstat (MPO inhibitor)

890655-80-8

Immunity and inflammation

1mg;5mg;10mg;25mg;100mg

Z414184

Zanubrutinib (BGB-3111) (BTK inhibitor)

1691249-45-2

Immunity and inflammation

2mg;5mg;25mg;50mg

C127776

Crenolanib (CP-868596) (CSF1R inhibitor)

670220-88-9

Immunity and inflammation

5mg;10mg;25mg;50mg;100mg

O414422

Orelabrutinib (ICP-022) (BTK inhibitor)

1655504-04-3

Immunity and inflammation

5mg;10mg;25mg;50mg

C193834

Chloroquine (TLR9 inhibitor)

NSC-187208

Immunity and inflammation

250mg;1g;5g;25g

B275738

Belnacasan (VX-765) (caspase-1 inhibitor)

273404-37-8

Immunity and inflammation

5mg;10mg;25mg;
50mg;100mg;250mg

S293790

Rapamycin (FKBP1A inhibitor)

53123-88-9

Immunity and inflammation

50mg;250mg;1g

T129491

Tranilast (RAAS; PGD2 inhibitor)

53902-12-8

Endocrinology and hormones

250mg;1g;5g;25g;100g

C275378

7-Cl-O-Nec1 (receptor interacting serine/threonine kinase 1 inhibitor)

852391-15-2

Apoptosis

5mg;25mg;50mg;

100mg;250mg

G414090

GSK'963 (RIPK1 inhibitor)

2049868-46-2

Apoptosis

1mg;5mg;25mg;100mg

G414024

GSK2982772 (RIPK1 inhibitor)

1622848-92-3

Apoptosis

5mg;10mg;25mg;50mg;100mg

G414274

GSK2983559 (compound 3) 
(RIPK2 inhibitor)

1579965-12-0

Apoptosis

5mg;10mg;25mg;50mg

G414181

GSK547 (RIPK1 inhibitor)

2226735-55-1

Apoptosis

5mg;25mg;100mg

G286537

GSK 583 (RIPK2 inhibitor)

1346547-00-9

Apoptosis

5mg;10mg;25mg;50mg

R413493

RIPA-56 (RIPK1 inhibitor)

1956370-21-0

Apoptosis

5mg;10mg;25mg;
50mg;100mg;200mg

S127897

KD025 (SLx-2119) (ROCK1 inhibitor)

911417-87-3

Cytoskeleton

5mg;10mg;25mg;
50mg;100mg;250mg

R127149

RG7112 
(MDM2 proto-oncogene inhibitor)

939981-39-2

Cell cycle

5mg;10mg;25mg;50mg;100mg

A414162

Adavivint (SM04690) 
(CDC like kinase 2 inhibitor)

1467093-03-3

Cell cycle

5mg;25mg;100mg

B126947

BX-795 (AURKB inhibitor)

702675-74-9

Cell cycle

1mg;10mg;50mg;100mg

H413999

HG-9-91-01 (SIK1 inhibitor)

1456858-58-4

Cell cycle

5mg;25mg;100mg

T413733

TAK-632 (AURKB inhibitor)

1228591-30-7

Cell cycle

5mg;10mg;25mg;50mg;100mg

T288176

Takinib (CLK2 inhibitor)

1111556-37-6

Cell cycle

5mg;10mg;25mg;50mg;100mg

T413958

Tomivosertib (eFT-508) (CLK4 inhibitor)

1849590-01-7

Cell cycle

1mg;5mg;10mg;
25mg;50mg;100mg;250mg

U413938

umbralisib (TGR-1202) (CSNK1E inhibitor)

1532533-67-7

Cell cycle

5mg;10mg;25mg;50mg;100mg

H107067

Harmine (DYRK1A inhibitor)

442-51-3

Cell cycle

250mg;1g

B127687

Baricitinib (AAK1 inhibitor)

1187594-09-7

Cell cycle

5mg;10mg;50mg;250mg;1g

D413851

Dubermatinib(TP-0903)

(AURKA inhibitor)

1341200-45-0

Cell cycle

5mg;10mg;25mg;50mg;100mg

A340149

Apilimod (PIKFYVE inhibitor)

541550-19-0

Cell cycle

25mg;50mg;100mg;250mg;1g

 

Binding Agent

Cat.No

Product Name

CAS

Research Category

Size

A413866

Avadomide (CRBN binding agent)

1015474-32-4

Ubiquitination

2mg;5mg;25mg;50mg;100mg

L125046

Lenalidomide (CRBN binding agent)

191732-72-6

Ubiquitination

50mg;250mg;1g;5g;

10g;25g;100g

I414161

Iberdomide (CC220) 
(CRBN binding agent)

1323403-33-3

Immunity and inflammation

2mg;5mg;10mg;

25mg;50mg;100mg

 

Aladdin:https://www.aladdinsci.com/

Categories: Technical articles

Da — when not otherwise indicated, molecular weight units are daltons.   Mw — weight-average molecular weight.   Mn — number-average molecular weight.

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Cite this article

Aladdin Scientific. "Aladdin®Ligands of Immunopharmacology" Aladdin Knowledge Base, updated Dec 20, 2024. https://www.aladdinsci.com/us_en/faqs/aladdin-ligands-of-immunopharmacology-en.html
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