Muromonab (anti-CD3) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD3, >95%, Mouse IgG2a

CAS: 140608-64-6 Cat. No.: Ab170491
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Mouse
Reactive species
Human
Isotype
Mouse IgG2a
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab170491-100μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
135,90US$
1mg
Ab170491-1mg
1
679,90US$
5mg
Ab170491-5mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
1.699,90US$
10mg
Ab170491-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
2.739,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Muromonab (anti-CD3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab (anti-CD3) specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab (anti-CD3) blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab (anti-CD3) can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients.

Specifications

Product Name
Muromonab (anti-CD3) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD3, >95%, Mouse IgG2a
Sinónimos
CD_antigen: CD3e | CD3 antigen, delta subunit | CD3 | CD3d antigen | CD3d antigen, delta polypeptide (TiT3 complex) | CD3d molecule, delta (CD3-TCR complex) | CD3-DELTA | CD3e antigen | CD3e antigen, epsilon polypeptide (TiT3 complex) | CD3e molecule, eps
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Mecanismos bioquímicos y fisiológicos
The CD3 complex mediates signal transduction.
Especies hospedadoras
Mouse
Especificidad
CD3
Aplicación
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de anticuerpo
Primary antibody
Clonalidad
Recombinant
Isotipo
Mouse IgG2a
Tipo de cadena ligera
kappa
SDS-PAGE
146.34 kDa
Método de purificación
Protein A purified
Pureza
>95%
Fuente
CHO supernatant
Concentración
See COA
CAS
140608-64-6
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 with Muromonab (anti-CD3) (Ab170491) (right panel) conjugated with biotin compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 (red) with Muromonab (anti-CD3) (Ab170491) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Muromonab (anti-CD3) (Ab170491) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Muromonab (anti-CD3) (Ab170491). Goat Anti-Human IgG (FITC) (Ab175834) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Muromonab (anti-CD3) (Ab170491) - SEC
The purity of Muromonab (anti-CD3) (Ab170491) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0708072Certificate of AnalysisMay 19, 2026 Ab170491
ZJ23F1001371Certificate of AnalysisAug 12, 2025 Ab170491
ZJ23F1001372Certificate of AnalysisAug 12, 2025 Ab170491
ZJ26F0636103Certificate of AnalysisAug 12, 2025 Ab170491
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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