2-Mercaptoethanol - ≥99% , CAS No.60-24-2

CAS: 60-24-2 Cat. No.: M301573 Formula: C₂H₆OS Molecular Weight: 78.13 Beilstein Registry Number: 773648 EC Number: 200-464-6

GRADE & PURITY ≥99%

Synonyms

beta-Hydroxyethylmercaptan | mercaptoethyl alcohol | Monothioethyleneglycol | Thiomonoglycol | STL482546 | C00928 | .beta.-Hydroxyethylmercaptan | EN300-19346 | MFCD00004890 | 2-Hydroxyethyl mercaptan | .beta.-Hydroxyethanethiol | 2-Hydroxyethanethiol | 2

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice,FedEx DG Service

Overview

2-mercaptoethanol is a thiol compound, commonly used as a reducing agent in organic reactions.

Application：

2-mercaptoethanol is widely used for retarding oxidation of biological compounds in solution.
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Specifications

Synonyms

beta-Hydroxyethylmercaptan | mercaptoethyl alcohol | Monothioethyleneglycol | Thiomonoglycol | STL482546 | C00928 | .beta.-Hydroxyethylmercaptan | EN300-19346 | MFCD00004890 | 2-Hydroxyethyl mercaptan | .beta.-Hydroxyethanethiol | 2-Hydroxyethanethiol | 2

Specifications & Purity

≥99%

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice,FedEx DG Service

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

Pubchem Sid

508811312

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508811312

Canonical Smiles

C(CS)O

IUPAC Name

2-sulfanylethanol

InChIKey

DGVVWUTYPXICAM-UHFFFAOYSA-N

INCHI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

Isomeric SMILES

C(CS)O

WGK Germany

3

RTECS

KL5600000

UN Number

UN 2966

Packing Group

II

Molecular Weight

78.13

Beilstein

773648

Reaxy-Rn

773648

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=773648&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organosulfur compounds
    • Class Thiols
      • Subclass Alkylthiols

• Kingdom: Organic compounds
• Superclass: Organosulfur compounds
• Class: Thiols
• Subclass: Alkylthiols
• Intermediate Tree Nodes: Not available
• Direct Parent: Alkylthiols
• Alternative Parents: Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alkylthiol - Organic oxygen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alkylthiols. These are organic compounds containing the thiol functional group linked to an alkyl chain.
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CA2 Tclin Carbonic anhydrase II (17698 Activities)

Discover Target: CA2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA9 Tclin Carbonic anhydrase IX (8255 Activities)

Discover Target: CA9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Miscible with water, alcohol, ether, benzene and other organic solvents.
• Sensitivity: Moisture & Air & heat Sensitive.
• Refractive Index: 1.499-1.502
• Flash Point(°F): 167℉
• Flash Point(°C): 75℃
• Boil Point(°C): 157-158°C
• Melt Point(°C): -100°C
• Molecular Weight: 78.140 g/mol
• XLogP3: -0.200
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 78.0139 Da
• Monoisotopic Mass: 78.0139 Da
• Topological Polar Surface Area: 21.200 Ų
• Heavy Atom Count: 4
• Formal Charge: 0
• Complexity: 10.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1