Urea - UltraBio™, Suitable for molecular biology, ≥99.5%(T) , CAS No.57-13-6

CAS: 57-13-6 Cat. No.: U111902 Formula: H2NCONH2 Molecular Weight: 60.06 Beilstein Registry Number: 635724 EC Number: 200-315-5 PubChem CID: 1176
AVAILABLE TO ORDER
GRADE & PURITY UltraBio™ ? UltraBio™ — Aladdin's line for molecular-biology applications. Use for nuclease-free, high-consistency reagents across molecular workflows. Suitable for molecular biology ? Molecular-biology grade — free of nucleases and contaminants that degrade DNA/RNA. Use in cloning, PCR, and nucleic-acid work needing clean reagents. ≥99.5%(T)
Synonyms
Carbonyldiamide | Onychomal | Ultra Mide | UNII-8W8T17847W | UREA [EP MONOGRAPH] | UREA COMPONENT OF CALMURID HC | Ureacin-10 lotion | EINECS 200-315-5 | Urevert | CALMURID HC COMPONENT UREA | Carbamide;Carbonyldiamide | Carbonyldiamine | Panafil | Urea (
Storage
Room temperature,Desiccated
Shipped In
Normal
★
Size
USA
Germany (EU)*
Price
Qty
25g
U111902-25g
7 In stock
—
$10.90
100g
U111902-100g
9 In stock
3 In stock
$17.90
500g
U111902-500g
3 In stock
—
$48.90
Enter a quantity for the sizes you want to add.
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Why this grade

UltraBio™, Suitable for molecular biology, ≥99.5%(T) Suitable for molecular biology,UltraBio™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 4775 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Carbonyldiamide | Onychomal | Ultra Mide | UNII-8W8T17847W | UREA [EP MONOGRAPH] | UREA COMPONENT OF CALMURID HC | Ureacin-10 lotion | EINECS 200-315-5 | Urevert | CALMURID HC COMPONENT UREA | Carbamide;Carbonyldiamide | Carbonyldiamine | Panafil | Urea (
Specifications & Purity
UltraBio™, Suitable for molecular biology, ≥99.5%(T)
Biochemical and Physiological Mechanisms
Urea participates in the metabolism of nitrogen-containing substances. When used as fertilizer, it can serve as a nitrogen source. Urea is used to manufacture compounds. It is widely used as fertilizer and animal feed additive in the agricultural field, a
Storage
Room temperature,Desiccated
Shipped In
Normal
Grade
Suitable for molecular biology, UltraBio™
Purity
≥99.5%(T)
Names and Identifiers
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/508813336
Canonical Smiles
C(=O)(N)N
IUPAC Name
urea
InChIKey
XSQUKJJJFZCRTK-UHFFFAOYSA-N
INCHI
1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
Isomeric SMILES
C(=O)(N)N
WGK Germany
1
RTECS
YR6250000
PubChem CID
1176
Molecular Weight
60.06
Beilstein
635724

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassOrganic carbonic acids and derivatives
SubclassUreas
Intermediate Tree Nodes Not available
Direct ParentUreas
Alternative Parents Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Urea - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as ureas. These are compounds containing two amine groups joined by a carbonyl (C=O) functional group.
External Descriptors a small molecule
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
OR51E2 Tchem Olfactory receptor 51E2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caco-2 (12174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Skin (286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C5 Tclin Complement C5 (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Brain (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ureB Urease subunit alpha/Urease subunit beta (701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

52 results found

Lot NumberCertificate TypeDateItem
B2318333Certificate of AnalysisAug 03, 2026 U111902
B2301240Certificate of AnalysisJul 30, 2026 U111902
B2301242Certificate of AnalysisJul 30, 2026 U111902
F2604621Certificate of AnalysisMay 19, 2026 U111902
F2604620Certificate of AnalysisMay 19, 2026 U111902
F2604618Certificate of AnalysisMay 19, 2026 U111902
F2604602Certificate of AnalysisMay 19, 2026 U111902
F2604588Certificate of AnalysisMay 19, 2026 U111902
L2511636Certificate of AnalysisDec 02, 2025 U111902
L2511635Certificate of AnalysisDec 02, 2025 U111902
L2511634Certificate of AnalysisDec 02, 2025 U111902
L2511629Certificate of AnalysisDec 02, 2025 U111902
L2511628Certificate of AnalysisDec 02, 2025 U111902
A2431052Certificate of AnalysisOct 29, 2025 U111902
A2431054Certificate of AnalysisOct 29, 2025 U111902
E2322210Certificate of AnalysisFeb 07, 2025 U111902
I2523061Certificate of AnalysisNov 11, 2024 U111902
L2406783Certificate of AnalysisNov 11, 2024 U111902
L2406748Certificate of AnalysisNov 11, 2024 U111902
L2406744Certificate of AnalysisNov 11, 2024 U111902
L2406725Certificate of AnalysisNov 11, 2024 U111902
K2504121Certificate of AnalysisNov 11, 2024 U111902
K2426773Certificate of AnalysisNov 11, 2024 U111902
I2410192Certificate of AnalysisAug 20, 2024 U111902
I2410191Certificate of AnalysisAug 20, 2024 U111902
I2410188Certificate of AnalysisAug 20, 2024 U111902
I2410189Certificate of AnalysisAug 20, 2024 U111902
I2410190Certificate of AnalysisAug 20, 2024 U111902
A2431049Certificate of AnalysisJan 19, 2024 U111902
A2431319Certificate of AnalysisJan 19, 2024 U111902
A2431057Certificate of AnalysisJan 19, 2024 U111902
E2322190Certificate of AnalysisApr 23, 2023 U111902
K2314083Certificate of AnalysisApr 23, 2023 U111902
E2322187Certificate of AnalysisApr 23, 2023 U111902
E2322191Certificate of AnalysisApr 23, 2023 U111902
E2322204Certificate of AnalysisApr 23, 2023 U111902
D2426082Certificate of AnalysisApr 23, 2023 U111902
I2405026Certificate of AnalysisApr 23, 2023 U111902
B2318302Certificate of AnalysisJan 16, 2023 U111902
B2318337Certificate of AnalysisJan 16, 2023 U111902
B2318335Certificate of AnalysisJan 16, 2023 U111902
B2318329Certificate of AnalysisJan 16, 2023 U111902
B2318320Certificate of AnalysisJan 16, 2023 U111902
K2218879Certificate of AnalysisOct 29, 2022 U111902
K22181078Certificate of AnalysisOct 29, 2022 U111902
K2218906Certificate of AnalysisOct 29, 2022 U111902
K2218905Certificate of AnalysisOct 29, 2022 U111902
K2218895Certificate of AnalysisOct 29, 2022 U111902
K2218894Certificate of AnalysisOct 29, 2022 U111902
K2218893Certificate of AnalysisOct 29, 2022 U111902
K2218860Certificate of AnalysisOct 29, 2022 U111902
I2008273Certificate of AnalysisJul 12, 2022 U111902
Chemical and Physical Properties
SolubilitySoluble in water, methanol, ethanol, slightly soluble in ether, chloroform, and benzene.
SensitivityMoisture sensitive.
Melt Point(°C)132-135 °C (lit.)
Molecular Weight60.056 g/mol
XLogP3-1.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass60.0324 Da
Monoisotopic Mass60.0324 Da
Topological Polar Surface Area69.100 Ų
Heavy Atom Count4
Formal Charge0
Complexity29.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Nucleic Acid Electrophoresis Workflow—5 Main Steps
Molecular Biology Grade
Comparing Guanidine Hydrochloride and Urea for Inclusion-Body Solubilization
Common Questions and Answers for SDS-PAGE Experiments
Common Reagents for Reducing Protein Disulfide Bonds
Why Did My Ni-Agarose Beads Turn Black or Brown?
How to Optimize Buffer Components for Ni-Agarose Beads
Obtaining soluble and biologically active recombinant proteins from inclusion bodies
Eight Common Lysis Buffers
His-Tagged Protein Purification
Biotin-Labeled Protein Purification
His-Tag Protein Purification: Common Troubleshooting Questions and Practical Solutions
Nucleic Acid and Nuclease Decontamination in Biopharmaceutical Manufacturing and Molecular Testing Workflows
How to Choose a Hydrogen Evolution (HER) Catalyst: Kinetic Barriers in Water Electrolysis, AWE/PEM/AEM Pathways, and a Materials-Family Roadmap (with a Product Map)
How to Purify Proteins by Ion-Exchange Chromatography Under Denaturing Condition
A Practical Guide to Small-Molecule Chemical Probes: Concept Clarification, Causal Validation, and Experimental Selection (with Product Navigation and Tables A–D)
Endoproteinase Lys-C: Mechanism, Applications, and Method-Control Considerations for Lysine-Specific Digestion
A Review of Ten Commonly Used Techniques for Detection, Quantification, and Interaction Analysis in Nucleic Acid Research
Protein Tags Demystified: Classification, Properties, and Suitable Experimental Applications
Key Enzymes in Amino Acid Metabolism: A Mechanistic Framework and Research Applications
Why Metal Nanocatalysts Can “Save Energy Yet Lose Performance Easily”: Durability Logic from Active Sites to Support/Interface Engineering (Including Selection Guide and Product Tables A–D)
Proteinase K: Frequently Asked Questions
Plant Omics Panorama: Workflow Frameworks and Multi-Omics Integration from Genomics to Transcriptomics, Proteomics, and Metabolomics
Whey Protein: Composition Profile, Manufacturing Routes, and Key Product-Type Essentials
Review of Chymotrypsin: Enzymological Properties, Catalytic Mechanism, and Research Applications
Glycoprotein Hormone Family: Molecular Features, Signaling Bias, and In Vivo Pharmacokinetics
Roles of the Carboxypeptidase Family in Protein C-Terminal Processing and Experimental Analysis
Methodological Studies on Glycoprotein Structural Characterization and Quality Attribute Analysis
Research Framework for Multi-Enzyme Digestion Strategies and Optimization of Proteomic Coverage
Technical Comparison and Method Selection for Hydroxyproline Determination
Decision Logic for Peptide Synthesis Routes: Applicability and Criteria for Choosing among SPPS, LPPS, and Recombinant Expression
Thiol and Disulfide Status in Biological Samples: Detection Methods and Applications
Perovskite Oxides for Energy and Environmental Catalysis: How Oxygen Vacancies, B-Site Metals, and the Metal–Oxygen Bond Network Regulate Reaction Performance
Experimental Research on Candidate Probiotics: From Strain Identification and Mechanistic Evaluation to Product Selection
Comparison of Urea Detection Methods: Reaction Mechanisms, Interference Factors, and Application Scenarios of the Urease Method and Diacetyl Monoxime Method
Solvents, Co-solvents, and Solubilization Systems in Home and Personal Care Formulations: Classification, Functions, and Selection Guide
Why Do Alcohols Differ in Function: Why Is Glycerol Mainly Moisturizing, Propylene Glycol Mainly Solubilizing, and Isopropyl Alcohol Fast-Drying? — Understanding Personal Care Formulation Functions from Structural Differences
What Is Synthetic Biology? The Industrialization Pathway from Upstream Reagent Toolchains to Biomanufacturing Applications
Structure, Properties, and Mechanisms of Powdered Fragrances and Fragrance Delivery Materials: Stability, Release Mechanisms, and Selection Logic
Understanding Ceramides from the Perspective of the Stratum Corneum Lipid Barrier: Moisturizing and Barrier-Repair Mechanisms, Ingredient Selection, and Formulation Research Considerations
How Sodium Cumenesulfonate Improves the Stability of Water-Based Cleaning Formulations: From Structure and Phase Behavior to Selection Criteria
Evaluation of Blood-Brain Barrier Permeability: Tracer Extravasation, TEER Measurement, and Interpretation of In Vitro Model Results
Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications
The Dual-Targeted Skin-Brightening Mechanism of 4-MSK: Inhibiting Melanin Production and Reducing Epidermal Pigment Retention
Moisturizing Mechanism of Polyglutamic Acid: From the γ-Glutamyl Structure to Hydration Networks and Surface Film-Forming Behavior
Probiotics, Prebiotics, and Postbiotics in Skin Care: Conceptual Distinctions, Mechanisms of Action, and Their Applications in the Care of Dry, Itchy, and Rough Skin
The Moisturizing and Low-Moisture Protective Mechanisms of Trehalose: From Its α,α-1,1 Structure and Hydration Dynamics to In Vitro Skin Barrier Research
Protective and Potential Reparative Mechanisms of Prinsepia utilis Seed Oil on the Skin Barrier: Fatty Acid Composition, Epidermal Lipid Metabolism, and Research Evidence
Structure, Stratum Corneum Distribution, and Stratum Corneum Conditioning Mechanism of Capryloyl Salicylic Acid: Barrier Effects and Safety Evaluation
The Sebum-Regulating Potential of Zinc PCA and Its Relationship with Stratum Corneum Hydration
Mechanisms by Which Fructan-Rich Ophiopogon japonicus Tuberous Root Extract Supports Skin Moisturization and Barrier Function
Multilevel Moisturizing Mechanisms of Sodium Hyaluronate and Its Derivatives: Molecular Weight Modulation, Crosslinking, Acetylation, and Major Sites of Action
What Is “Plant Collagen”? Distinguishing Ingredient Types, Structural Differences, Production Methods, and Skincare Effects
Mechanisms of Action, Formulation Screening, and Safety Evaluation of Solubilizers, Hydrotropes, and Cosolvents in Drug-Delivery Systems
How Ectoine Regulates Skin Hydration: Zwitterionic Structure, Preferential Hydration, and Barrier-Support Mechanisms
Direct Construction of Methylsulfonyl-Containing Heterocycles: Synthesis and Applications of Prefunctionalized Three-Carbon Vinamidinium Salts
Stratum Corneum Penetration and Skin Mechanisms of Panthenol: Moisturization, Barrier Repair, and Soothing Effects
Citations of This Product
Solution Calculators
Reviews

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