Name: Ethylenediaminetetraacetic acid(EDTA) - ≥98% , CAS No.60-00-4
Brand: Aladdin Scientific
SKU: E278775
Availability: InStock

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates (CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product Solution Calculators Reviews

🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1010 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Soluble in sodium hydroxide, sodium carbonate and ammonia solution, soluble in 162 minutes boiling water, slightly soluble in cold water, insoluble in alcohol and general organic solvents.

Calcium ion complexing agent, detergent, blood anticoagulant. Used as calcium chelating agent in biochemical research to eliminate the inhibition of enzyme-catalyzed reaction caused by trace heavy metals.

Specifications

Synonyms

Specifications & Purity

≥98%

Storage

Room temperature,Desiccated

Shipped In

Normal

Purity

≥98%

Names and Identifiers

Pubchem Sid

504750993

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504750993

Canonical Smiles

C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

IUPAC Name

2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid

InChIKey

KCXVZYZYPLLWCC-UHFFFAOYSA-N

INCHI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

Isomeric SMILES

C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

Molecular Weight

292.24

Reaxy-Rn

1716295

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1716295&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

<<<<<<< HEAD Download SDS → ======= Download SDS → >>>>>>> release248-p3

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Tetracarboxylic acids and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Tetracarboxylic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Tetracarboxylic acids and derivatives
Alternative Parents	Alpha amino acids Trialkylamines Amino acids Carboxylic acids Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Tetracarboxylic acid or derivatives - Alpha-amino acid - Alpha-amino acid or derivatives - Amino acid or derivatives - Tertiary amine - Tertiary aliphatic amine - Amino acid - Carboxylic acid - Organopnictogen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organic oxygen compound - Hydrocarbon derivative - Amine - Organic oxide - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as tetracarboxylic acids and derivatives. These are carboxylic acids containing exactly four carboxyl groups.
External Descriptors	ethylenediamine derivative - polyamino carboxylic acid - tetracarboxylic acid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD2 Tclin Dopamine D2 receptor (23596 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH2 Tclin Histamine H2 receptor (5428 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)

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SLC6A4 Tclin Serotonin transporter (12625 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH1 Tclin Histamine H1 receptor (7573 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRD1 Tclin Delta opioid receptor (15096 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRK1 Tclin Kappa opioid receptor (16155 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC29A1 Tclin Equilibrative nucleoside transporter 1 (1711 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2C Tclin Alpha-2c adrenergic receptor (4876 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA2A Tclin Adenosine A2a receptor (16305 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

blaZ Beta-lactamase (285 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mc4r Melanocortin receptor 4 (1205 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp13 Matrix metalloproteinase 13 (19 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Npy1r Neuropeptide Y receptor type 1 (8 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cckar Cholecystokinin A receptor (90 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pde4d Phosphodiesterase 4D (4 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Escherichia coli (133304 Activities)

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Enterococcus faecalis (29875 Activities)

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Mycolicibacterium smegmatis (8003 Activities)

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Candida parapsilosis (8521 Activities)

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Mus musculus (284745 Activities)

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Carbapenem-hydrolizing beta-lactamase SFC-1 (31 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

imiA IMI-1 (34 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

bla Carbepenem-hydrolyzing beta-lactamase KPC (120 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudoalteromonas (41 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ileum (29 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

blaVIM-13 Class B carbapenemase VIM-13 (33 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

blaVIM Beta-lactamase VIM-1 (33 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

bla2 Beta-lactamase II (21 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cell membrane (1233 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

cAMP-specific 3',5'-cyclic phosphodiesterase 4B (18 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

bla(NDM-4) Metallo-beta-lactamase NDM-4 (34 Activities)

Discover Target: bla(NDM-4)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Certificates (CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

63 results found

Lot Number	Certificate Type	Date	Item
F2630383	Certificate of Analysis	Jun 17, 2026	E278775
F2630333	Certificate of Analysis	Jun 17, 2026	E278775
F2630332	Certificate of Analysis	Jun 17, 2026	E278775
F2630331	Certificate of Analysis	Jun 17, 2026	E278775
F2630416	Certificate of Analysis	Jun 17, 2026	E278775
C2616708	Certificate of Analysis	Mar 04, 2026	E278775
C2616707	Certificate of Analysis	Mar 04, 2026	E278775
C2616706	Certificate of Analysis	Mar 04, 2026	E278775
C2616672	Certificate of Analysis	Mar 04, 2026	E278775
C2616705	Certificate of Analysis	Mar 04, 2026	E278775
J2513314	Certificate of Analysis	Sep 30, 2025	E278775
J2513317	Certificate of Analysis	Sep 30, 2025	E278775
L2523391	Certificate of Analysis	Sep 30, 2025	E278775
L2523386	Certificate of Analysis	Sep 30, 2025	E278775
L2523384	Certificate of Analysis	Sep 30, 2025	E278775
L2523381	Certificate of Analysis	Sep 30, 2025	E278775
J2513336	Certificate of Analysis	Sep 30, 2025	E278775
J2513335	Certificate of Analysis	Sep 30, 2025	E278775
J2513315	Certificate of Analysis	Sep 30, 2025	E278775
I2509380	Certificate of Analysis	Jul 14, 2025	E278775
I2509379	Certificate of Analysis	Jul 14, 2025	E278775
G2524524	Certificate of Analysis	Jul 14, 2025	E278775
G2524493	Certificate of Analysis	Jul 14, 2025	E278775
G2524492	Certificate of Analysis	Jul 14, 2025	E278775
G2524446	Certificate of Analysis	Jul 14, 2025	E278775
I2509381	Certificate of Analysis	Jul 14, 2025	E278775
I2509385	Certificate of Analysis	Jul 14, 2025	E278775
G2524447	Certificate of Analysis	Jul 14, 2025	E278775
E2507329	Certificate of Analysis	Apr 22, 2025	E278775
E2507325	Certificate of Analysis	Apr 22, 2025	E278775
E2507324	Certificate of Analysis	Apr 22, 2025	E278775
E2507322	Certificate of Analysis	Apr 22, 2025	E278775
E2507319	Certificate of Analysis	Apr 22, 2025	E278775
C2507395	Certificate of Analysis	Feb 26, 2025	E278775
C2507396	Certificate of Analysis	Feb 26, 2025	E278775
C2507397	Certificate of Analysis	Feb 26, 2025	E278775
C2507398	Certificate of Analysis	Feb 26, 2025	E278775
B2515072	Certificate of Analysis	Feb 19, 2025	E278775
I2424333	Certificate of Analysis	Sep 12, 2024	E278775
I2424335	Certificate of Analysis	Sep 12, 2024	E278775
I2424336	Certificate of Analysis	Sep 12, 2024	E278775
I2424337	Certificate of Analysis	Sep 12, 2024	E278775
A2509034	Certificate of Analysis	Sep 12, 2024	E278775
E2420209	Certificate of Analysis	May 07, 2024	E278775
E2420207	Certificate of Analysis	May 07, 2024	E278775
I2413078	Certificate of Analysis	Apr 18, 2023	E278775
E2304070	Certificate of Analysis	Apr 18, 2023	E278775
E2304047	Certificate of Analysis	Apr 18, 2023	E278775
J2313145	Certificate of Analysis	Apr 18, 2023	E278775
K2323047	Certificate of Analysis	Apr 18, 2023	E278775
B2302387	Certificate of Analysis	Nov 15, 2022	E278775
K2229698	Certificate of Analysis	Nov 15, 2022	E278775
K2229513	Certificate of Analysis	Nov 15, 2022	E278775
K2229639	Certificate of Analysis	Nov 15, 2022	E278775
D2419057	Certificate of Analysis	Nov 15, 2022	E278775
I2228199	Certificate of Analysis	Oct 24, 2022	E278775
H2217392	Certificate of Analysis	Jul 23, 2022	E278775
H2217391	Certificate of Analysis	Jul 23, 2022	E278775
L2301160	Certificate of Analysis	Jul 23, 2022	E278775
C2418056	Certificate of Analysis	Jul 23, 2022	E278775
H2217386	Certificate of Analysis	Jul 23, 2022	E278775
B2401036	Certificate of Analysis	Jul 23, 2022	E278775
G2306142	Certificate of Analysis	Jul 23, 2022	E278775

Chemical and Physical Properties

Solubility	The solubility in water at 25℃ is 0.5g/l. Insoluble in cold water, alcohol and common organic solvents. Dissolved in sodium hydroxide, sodium carbonate and ammonia solution.
Melt Point(°C)	220°C
Molecular Weight	292.240 g/mol
XLogP3	-5.900
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	11
Exact Mass	292.091 Da
Monoisotopic Mass	292.091 Da
Topological Polar Surface Area	156.000 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	315.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Protein purification

Differences Among Antibodies for WB/FC/IP/ChIP/IF/IHC

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Antibodies Protein Research

His-Tagged Protein Purification

Categories: Laboratory Protocols & SOPs Library

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Protein purification His-Tagged Protein Purification

PEG–Dialysis Tubing Method for Protein Concentration

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PEG–Dialysis Tubing Method for Protein Concentration

GST-Tagged Protein Purification

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Protein purification Glutathione S-transferase GST-Tagged Protein Purification GST

Magnetic Bead Isolation and Flow Cytometric Identification of Human Peripheral Blood CD4⁺ T Cells

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PBMC CD4+T

7 Types of DNA Ligases: Functions and Features

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DNA ligases

A Comprehensive Overview of Zinc Ion Fluorescent Probes: From TSQ / Zinquin to ZnAF / Zinpyr-1 – Mechanistic Comparison and Aladdin Selection Guide

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Fluorescent probes Zn Zinc ion fluorescent probe

Protease & Phosphatase Inhibitor Cocktails: Research Applications and Principles

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Cell lysis Protein extraction Tissue homogenate

Tyrosinase: a key regulatory enzyme in melanin synthesis and its biological and applied significance

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Oxidizing agent Molecular oxygen

Molecular Mechanisms and Biomedical Applications of Heparinase

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Lytic enzyme

Molecular Mechanisms and Multidomain Applications of Inorganic Pyrophosphatase

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Inorganic pyrophosphatase

His-Tag Protein Purification: Common Troubleshooting Questions and Practical Solutions

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His-tag protein purification

Nucleic Acid and Nuclease Decontamination in Biopharmaceutical Manufacturing and Molecular Testing Workflows

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Nucleic acid Nuclease Biopharmaceutical

Technical Analysis and Application Guide for RNase Inhibitors

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RNase RNase Inhibitors

Laccase: Technical Characteristics, Optimization Strategies, and Industrial Application Progress

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laccase multicopper oxidase T1/T2/T3 copper centers laccase-mediator system immobilization protein engineering industrial decolorization biobleaching

Endoproteinase Lys-C: Mechanism, Applications, and Method-Control Considerations for Lysine-Specific Digestion

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Peptide Mapping Serine protease Lys-C Endoproteinase Lys-C Lysine-specific cleavage Denaturing digestion LC–MS Sequence coverage Missed cleavage rate Critical peptide monitoring Method validation

Protein Tags Demystified: Classification, Properties, and Suitable Experimental Applications

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protein tags affinity tags epitope tags fluorescent tags affinity purification

Proteinase K: Frequently Asked Questions

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Proteinase K

How Organic Acids “Stabilize a System”: Selection Logic via the pH Window, Salt Forms, and Metal-Ion Management (with a navigation guide to Tables A–E)

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Pharmaceuticals Organic Acids

Phycocyanin: A Review of Sources, Structural Features, Production Processes, Applications, and Claimed Benefits

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stability Fluorescent labeling phycocyanin C-phycocyanin R-phycocyanin phycobiliproteins natural edible colorant fluorescent phycocyanin

Amino Acid Oxidases: Oxygen-Dependent Oxidative Deamination Systems and Their Analytical and Applied Uses

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Biosensing FAD FMN Amino acid oxidase L-amino acid oxidase D-amino acid oxidase Oxidative deamination Hydrogen peroxide Chiral analysis Oxygen limitation

RNA Extraction Technologies: Method Systems, Operational Workflows, and Key Quality-Control Considerations

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RNA extraction RNase Magnetic beads Column-based method organic extraction DNase treatment A260/280 A260/230 RIN

Agarose Precast Gels: Composition, Advantages, and Application Workflows for Standardized Nucleic Acid Electrophoresis Matrices

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DNA Nucleic acid electrophoresis agarose precast gels RNA resolution pore size buffer system wells lot-to-lot consistency band sharpness gel extraction standardization high-throughput

Procyanidins: Structural Features and Key Points for Research and Application

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Epicatechin procyanidins OPC PPC catechin

Phytase: Enzymological Properties, Mechanism of Action, and Applications in Feed and Food

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submerged fermentation Phytase Phosphomonoesterase Phytate Myo-Inositol Hexakisphosphate Available Phosphorus Monogastric Animals Pelleting Stability Solid-State Fermentation

Chlorophyll: Structural Features, Physicochemical Properties, and Key Points for Research and Industrial Applications

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stability HPLC Fluorescence Magnesium chlorophyll chlorophyll a chlorophyll b porphyrin ring phytol pheophytin Cu/Zn complexes

Ferulic Acid: Structural Features, Preparation Routes, and Key Points for Research Applications

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ferulic acid 3-methoxy-4-hydroxycinnamic acid

Flavones: Structural Features, Physicochemical Properties, and Key Points for Research and Applications

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HPLC Antioxidation flavone C6–C3–C6 flavone glycosides O-glycosides C-glycosides C5-hydroxylation 5-deoxy flavones TLR/NF-κB heterologous biosynthesis

dsDNase-Mediated Hydrolysis of Double-Stranded DNA: Enzymatic Characteristics, Methodological Strategies, and Bioanalytical Applications

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Biopharmaceuticals double-stranded deoxyribonuclease dsDNase dsDNA hydrolysis nucleic-acid removal sample pretreatment contamination control

Alginate : An Overview of Extraction and Purification Processes, Quality Identification, and Multidomain Applications

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Quality control Alginate Sodium alginate Calcium alginate Brown algae M/G ratio Ionic crosslinking Identification

Functional Properties, Application Scenarios, and Manufacturing Processes of Maltotetraose (G4): A Review

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G4 Maltotetraose Maltooligosaccharide α-1,4-glycosidic bond Low sweetness High viscosity Anti-crystallization Acid and heat stability

Review of Chymotrypsin: Enzymological Properties, Catalytic Mechanism, and Research Applications

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Peptide Mapping Serine protease substrate specificity limited proteolysis catalytic triad Chymotrypsin Alpha-Chymotrypsin Oxyanion Hole Acyl-Enzyme Intermediate Methodological Quality Control

Clostridial Proteases: Classification, Molecular Mechanisms, and Research Applications

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clostridial proteases

Review of the Principles, Methods, and Application Considerations for Superoxide Dismutase Activity Determination

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Oxidative Stress activity assay Methodological standardization SOD Superoxide Dismutase NBT assay WST assay Pyrogallol Autoxidation Assay Xanthine Oxidase Assay Antioxidant Evaluation

The Golden Pair for Nucleic Acid Extraction: RNase A and Proteinase K

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Reducing agent Nucleic Acid Extraction Protein denaturation RNA degradation Protein degradation RNA protection Enzymatic Applications Genomic DNA Purification Molecular Diagnostics Viral Nucleic Acid Extraction

Tissue Dissociation for Single-Cell Preparation: Sample Handling and Quality Control Strategies

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cell viability single-cell preparation tissue processing sample quality control enzymatic digestion doublets declumping dead cell removal single-cell transcriptomics flow sorting

Decision Logic for Peptide Synthesis Routes: Applicability and Criteria for Choosing among SPPS, LPPS, and Recombinant Expression

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Peptide synthesis Liquid-phase peptide synthesis

Perovskite Oxides for Energy and Environmental Catalysis: How Oxygen Vacancies, B-Site Metals, and the Metal–Oxygen Bond Network Regulate Reaction Performance

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perovskite perovskite oxides oxide

What Are Polyamines? Structural Features, Classification and Representative Compounds, Applications, and Synthetic Strategies

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Organic chemistry Medicinal Chemistry Polyamine Multiple amine nitrogen atoms Nitrogen-containing organic compounds

The Role, Selection, and Validation of Chelating Agents in Daily Chemical Formulations

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Chelating Agents

From Structure to Rheology: How Carbomer Forms Gel Structures and Enables Thickening, Suspension, and Auxiliary Emulsion Stabilization

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Carbomer

From Structure to Selection: Mechanisms and Application Assessment of Low-Foam Oil and Wax Removal with Fatty Acid Methyl Ester Ethoxylates (FMEE)

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FMEE MEE

Sodium Metasilicate in Cleaning Applications: Hydration-Form Differences, Mechanisms of Action, and Selection Logic

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Na₂SiO₃ Sodium Metasilicate

Bone Tissue Decalcification Protocol: Rapid and Slow Methods

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Bone tissue decalcification

GITC——Key Reagent for Nucleic Acid Extraction and Sample Protection

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RNA extraction DNA extraction GITC Nucleic Acid Extraction Sample Protection Virus Inactivation Protein Denaturant Molecular Diagnosis

Phase-Partitioning Principles, System Differences, and Application Selection in Phenol-Based DNA and RNA Extraction

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RNA extraction DNA extraction Quality control phenol-based extraction phenol-chloroform isoamyl alcohol acidic phenol guanidinium thiocyanate liquid-liquid partitioning nucleic acid purification

What Determines Collagen Function: From Triple-Helix Formation to Hierarchical Assembly, Crosslink Maturation, and Dynamic Remodeling

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Collagen

The Combination Logic of Palmitoyl Tripeptide-1 and Palmitoyl Pentapeptide-4: Skin Delivery, Matrix Signaling, and Regulation of Collagen Homeostasis

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peptide palmitoyl chain

Differences Between Animal-Derived Collagen and Recombinant Collagen in Skincare: Sequence and Structure, Safety, Skin Effects, and Evidence Evaluation

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Animal-Derived Collagen Recombinant Human Collagen Recombinant Humanized Collagen Triple Helix Immunogenicity Skin Repair Transepidermal Water Loss

Regulatory Mechanisms of 5mC DNA Methylation

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Epigenetics DNA methylation 5mC DNMT TET 5hmC UHRF1 TDG

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