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UDP glucuronosyltransferases (UGT)

UDP-glucuronosyltransferases (UGTs) are a family of enzymes that play a crucial role in the process of glucuronidation, which is a major part of phase II metabolism 1. UGTs catalyze the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule, which is known as a glucuronidation reaction.