There are eight known members of the IAP family in humans: cIAP1, cIAP2, XIAP, NAIP, Survivin, Livin, Apollon, and BRUCE . Each member has a unique structure and function. For example, XIAP is the most potent inhibitor of apoptosis among the IAPs and is involved in regulating both intrinsic and extrinsic apoptotic pathways. Survivin is involved in regulating cell division and is overexpressed in many types of cancer.
Inhibitors of apoptosis (IAP) protein family
LCL161, Inhibitor of baculoviral IAP repeat containing 2;Inhibitor of X-linked inhibitor of apoptosisSpecifications & Purity: ≥99%
CAS No.: 1005342-46-0
Starting at $117.90
Birinapant, cIAP1/cIAP2 inhibitorSpecifications & Purity: 98%
CAS No.: 1260251-31-7
Starting at $82.90
BV-6, Inhibitor of baculoviral IAP repeat containing 2;Inhibitor of X-linked inhibitor of apoptosisCAS No.: 1001600-56-1
Starting at $1,334.90
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- AT406 (SM-406), Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
Specifications & Purity: ≥98%
CAS No.: 1071992-99-8
Starting at $97.90
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