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Analytical chromatography is a method of separating, identifying and quantifying the components of a mixture. It is widely used in the analysis of complex mixtures in various fields such as chemistry, biochemistry, environmental science, and medical research. Filler is a term used in analytical chromatography to refer to the material that is added to the stationary phase to increase its efficiency in separating the components of a mixture. Fillers can be in the form of particles, beads, or fibers, and their purpose is to increase the surface area of the stationary phase and to provide more sites for the components of the mixture to interact with. Fillers can be made of various materials, such as silica gel, polymers, or alumina, and their choice depends on the type of chromatography being performed and the nature of the components to be separated.
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