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TKL:Tyrosine kinase-like

TKL stands for Tyrosine Kinase-Like, which is a subfamily of protein kinases that are structurally similar to tyrosine kinases but lack the conserved tyrosine residue in their activation loop . TKLs are also known as non-receptor tyrosine kinases and are involved in various cellular processes, including cell growth, differentiation, and apoptosis . The TKL family includes Janus Kinase (JAK), Tyrosine Kinase 2 (TYK2), and B lymphocyte kinase (BLK), among others .

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  1. A-Raf proto-oncogene，serine/threonine kinase Inhibitor2item
  2. ABL proto-oncogene 1，non-receptor tyrosine kinase Inhibitor2item
  3. activin A receptor type 1 Inhibitor11item
  4. activin A receptor type 1B Inhibitor5item
  5. activin A receptor type 1C Inhibitor1 item
  6. activin A receptor type 2A Antibody1 item
  7. activin A receptor type 2B Antibody1 item
  8. activin A receptor type IL Inhibitor7item
  9. Activin receptors Agonist4item
  10. ALK receptor tyrosine kinase Inhibitor2item
  11. AMP kinase Inhibitor2item
  12. Anti-Müllerian hormone receptors Agonist1 item
  13. aurora kinase A Inhibitor2item
  14. aurora kinase B Inhibitor5item
  15. AXL receptor tyrosine kinase Inhibitor2item
  16. B-Raf proto-oncogene，serine/threonine kinase Inhibitor25item
  17. BLK proto-oncogene，Src family tyrosine kinase Inhibitor2item
  18. bone morphogenetic protein receptor type 2 Inhibitor2item
  19. bone morphogenetic protein receptor type IA Inhibitor6item
  20. bone morphogenetic protein receptor type IB Inhibitor5item
  21. Bone morphogenetic protein receptors Agonist8item
  22. c-ros oncogene 1，receptor tyrosine kinase Inhibitor1 item
  23. C-terminal Src kinase Inhibitor1 item
  24. casein kinase 1 gamma 1 Inhibitor1 item
  25. CDC like kinase 2 Inhibitor3item
  26. CDC42 binding protein kinase alpha Inhibitor1 item
  27. colony stimulating factor 1 receptor Inhibitor3item
  28. cyclin dependent kinase 1 Inhibitor2item
  29. cyclin dependent kinase 19 Inhibitor2item
  30. cyclin dependent kinase 2 Inhibitor2item
  31. cyclin dependent kinase 3 Inhibitor1 item
  32. cyclin dependent kinase 4 Inhibitor2item
  33. cyclin dependent kinase 5 Inhibitor2item
  34. cyclin dependent kinase 6 Inhibitor2item
  35. cyclin dependent kinase 7 Inhibitor1 item
  36. cyclin dependent kinase 8 Inhibitor3item
  37. cyclin dependent kinase 9 Inhibitor2item
  38. cyclin dependent kinase like 2 Inhibitor1 item
  39. death associated protein kinase 3 Inhibitor1 item
  40. discoidin domain receptor tyrosine kinase 1 Inhibitor2item
  41. discoidin domain receptor tyrosine kinase 2 Inhibitor3item
  42. DM1 protein kinase Inhibitor1 item
  43. doublecortin like kinase 1 Inhibitor2item
  44. doublecortin like kinase 2 Inhibitor2item
  45. dual specificity tyrosine phosphorylation regulated kinase 1B Inhibitor1 item
  46. dual specificity tyrosine phosphorylation regulated kinase 3 Inhibitor1 item
  47. EPH receptor A5 Inhibitor1 item
  48. EPH receptor A8 Inhibitor1 item
  49. EPH receptor B2 Inhibitor1 item
  50. epidermal growth factor receptor Inhibitor1 item
  51. eukaryotic translation initiation factor 2 alpha kinase 1 Inhibitor1 item
  52. FER tyrosine kinase Inhibitor1 item
  53. FES proto-oncogene，tyrosine kinase Inhibitor1 item
  54. FGR proto-oncogene，Src family tyrosine kinase Inhibitor2item
  55. fibroblast growth factor receptor 1 Inhibitor3item
  56. fibroblast growth factor receptor 2 Inhibitor1 item
  57. fibroblast growth factor receptor 3 Inhibitor3item
  58. fibroblast growth factor receptor 4 Inhibitor1 item
  59. fms related receptor tyrosine kinase 1 Inhibitor3item
  60. fms related receptor tyrosine kinase 3 Inhibitor5item
  61. fms related receptor tyrosine kinase 4 Inhibitor2item
  62. glycogen synthase kinase 3 alpha Inhibitor1 item
  63. glycogen synthase kinase 3 beta Inhibitor3item
  64. Growth/differentiation factor receptors Agonist5item
  65. indoleamine 2，3-dioxygenase 1 Inhibitor2item
  66. inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor1 item
  67. integrin linked kinase Inhibitor2item
  68. interleukin 1 receptor associated kinase 1 Inhibitor6item
  69. interleukin 1 receptor associated kinase 3 Inhibitor2item
  70. interleukin 1 receptor associated kinase 41 item
  71. interleukin 1 receptor associated kinase 4 Inhibitor15item
  72. Janus kinase 1 Allosteric modulator1 item
  73. Janus kinase 1 Inhibitor3item
  74. Janus kinase 2 Inhibitor7item
  75. Janus kinase 3 Inhibitor3item
  76. kinase insert domain receptor Inhibitor9item
  77. KIT proto-oncogene，receptor tyrosine kinase Inhibitor3item
  78. LCK proto-oncogene，Src family tyrosine kinase Inhibitor5item
  79. leucine rich repeat kinase 2 Inhibitor25item
  80. leukocyte receptor tyrosine kinase Inhibitor3item
  81. LIM domain kinase 1 Inhibitor10item
  82. LIM domain kinase 2 Inhibitor7item
  83. LYN proto-oncogene，Src family tyrosine kinase Inhibitor1 item
  84. MAPK/ERK Pathway2item
  85. mechanistic target of rapamycin kinase Inhibitor2item
  86. MER proto-oncogene，tyrosine kinase Inhibitor2item
  87. MET proto-oncogene，receptor tyrosine kinase Inhibitor2item
  88. microtubule affinity regulating kinase 3 Inhibitor1 item
  89. mitogen-activated protein kinase 10 Inhibitor3item
  90. mitogen-activated protein kinase 7 Inhibitor3item
  91. mitogen-activated protein kinase 8 Inhibitor3item
  92. mitogen-activated protein kinase 9 Inhibitor2item
  93. mitogen-activated protein kinase kinase 1 Inhibitor1 item
  94. mitogen-activated protein kinase kinase 2 Inhibitor1 item
  95. mitogen-activated protein kinase kinase 4 Inhibitor1 item
  96. mitogen-activated protein kinase kinase 5 Inhibitor1 item
  97. mitogen-activated protein kinase kinase 7 Inhibitor1 item
  98. mitogen-activated protein kinase kinase kinase 10 Inhibitor2item
  99. mitogen-activated protein kinase kinase kinase 11 Inhibitor3item
  100. mitogen-activated protein kinase kinase kinase 12 Inhibitor6item
  101. mitogen-activated protein kinase kinase kinase 13 Inhibitor1 item
  102. mitogen-activated protein kinase kinase kinase 14 Inhibitor3item
  103. mitogen-activated protein kinase kinase kinase 2 Inhibitor1 item
  104. mitogen-activated protein kinase kinase kinase 7 Inhibitor11item
  105. mitogen-activated protein kinase kinase kinase 9 Inhibitor6item
  106. mitogen-activated protein kinase kinase kinase kinase 2 Inhibitor2item
  107. mitogen-activated protein kinase kinase kinase kinase 3 Inhibitor1 item
  108. mitogen-activated protein kinase kinase kinase kinase 5 Inhibitor3item
  109. mixed lineage kinase domain like pseudokinase1 item
  110. mixed lineage kinase domain like pseudokinase Inhibitor2item
  111. myosin light chain kinase Inhibitor1 item
  112. neurotrophic receptor tyrosine kinase 1 Inhibitor2item
  113. neurotrophic receptor tyrosine kinase 2 Inhibitor3item
  114. neurotrophic receptor tyrosine kinase 3 Inhibitor2item
  115. NUAK family kinase 1 Inhibitor1 item
  116. p21 (RAC1) activated kinase 1 Inhibitor1 item
  117. p38 MAPK1 item
  118. phosphatidylinositol-4，5-bisphosphate 3-kinase catalytic subunit alpha Inhibitor2item
  119. phosphatidylinositol-4，5-bisphosphate 3-kinase catalytic subunit beta Inhibitor2item
  120. phosphatidylinositol-4，5-bisphosphate 3-kinase catalytic subunit delta Inhibitor2item
  121. phosphatidylinositol-4，5-bisphosphate 3-kinase catalytic subunit gamma Inhibitor2item
  122. Pim-1 proto-oncogene，serine/threonine kinase Inhibitor1 item
  123. platelet derived growth factor receptor beta Inhibitor4item
  124. protein kinase D1 Inhibitor2item
  125. protein kinase N1 Inhibitor1 item
  126. Protein Tyrosine Kinase/RTK1 item
  127. Raf1 item
  128. Raf-1 proto-oncogene，serine/threonine kinase Inhibitor23item
  129. receptor interacting serine/threonine kinase 1 Inhibitor28item
  130. receptor interacting serine/threonine kinase 2 Inhibitor11item
  131. receptor interacting serine/threonine kinase 3 Inhibitor8item
  132. Receptor tyrosine kinase (RTK) inhibitors1 item
  133. ret proto-oncogene Inhibitor3item
  134. Rho associated coiled-coil containing protein kinase 1 Inhibitor1 item
  135. Rho associated coiled-coil containing protein kinase 2 Inhibitor1 item
  136. ribosomal protein S6 kinase B1 Inhibitor1 item
  137. serine/threonine kinase 3 Inhibitor1 item
  138. serine/threonine kinase 4 Inhibitor1 item
  139. spleen associated tyrosine kinase Inhibitor3item
  140. SRC proto-oncogene，non-receptor tyrosine kinase Inhibitor4item
  141. SRSF protein kinase 2 Inhibitor1 item
  142. sugen kinase 110 Inhibitor1 item
  143. TANK binding kinase 1 Inhibitor1 item
  144. TEK receptor tyrosine kinase Inhibitor1 item
  145. testis associated actin remodelling kinase 1 Inhibitor3item
  146. testis associated actin remodelling kinase 2 Inhibitor3item
  147. testis specific serine kinase 1B Inhibitor1 item
  148. TNNI3 interacting kinase Inhibitor2item
  149. transforming growth factor beta receptor 1 Agonist1 item
  150. transforming growth factor beta receptor 1 Inhibitor14item
  151. transforming growth factor beta receptor 2 Agonist2item
  152. transforming growth factor beta receptor 2 Inhibitor5item
  153. Transforming growth factor β receptor Agonist3item
  154. TTK protein kinase Inhibitor2item
  155. tyrosine kinase 2 Allosteric modulator1 item
  156. tyrosine kinase 2 Inhibitor2item
  157. tyrosine kinase non receptor 2 Inhibitor1 item
  158. tyrosine kinase with immunoglobulin like and EGF like domains 1 Inhibitor1 item
  159. unc-51 like autophagy activating kinase 1 Inhibitor1 item
  160. ZAK sterile alpha motif and leucine zipper containing kinase AZK Inhibitor2item
    161. Show More⌵
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Action Type
  1. AGONIST22item
  2. ALLOSTERIC MODULATOR1 item
  3. ANTAGONIST1 item
  4. INHIBITOR166item
  5. NEGATIVE ALLOSTERIC MODULATOR1 item
Purity
  1. ≥97%1 item
  2. ≥98%5item
Price
  1. $0.00 - $499.9984item
  2. $500.00 - $999.9923item
  3. $1,000.00 - $1,499.9981item
  4. $2,500.00 - $2,999.991 item
  5. $7,500.00 and above1 item
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