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Fluorouracil

Specifications & Purity:  meets USP testing specifications
Item Number
F476739
Grouped product items
SKUSizeAvailabilityPrice Qty
F476739-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$497.90
F476739-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,203.90

Basic Description

Synonyms5-Fluorouracil|fluorouracil|51-21-8|5-FU|Fluoroplex|Efudex|Adrucil|Carac|Fluracil|Fluoroblastin|Queroplex|5-fluoropyrimidine-2,4(1H,3H)-dione|Phthoruracil|Carzonal|Kecimeton|Fluril|5-Fluoracil|Fluracilum|Timazin|Arumel|Efudix|Ulup|Fluorouracilum|Fluro Ura
Specifications & Puritymeets USP testing specifications

Names and Identifiers

IUPAC Name 5-fluoro-1H-pyrimidine-2,4-dione
INCHI InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChi Key GHASVSINZRGABV-UHFFFAOYSA-N
Canonical SMILES C1=C(C(=O)NC(=O)N1)F
Isomeric SMILES C1=C(C(=O)NC(=O)N1)F
WGK Germany 3
RTECS YR0350000
PubChem CID 3385
Molecular Weight 130.08
Beilstein 127172
Reaxy-Rn 127172

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Chemical and Physical Properties

Boil Point(°C)190 - 200 °C / 374 - 392 °F@ 0.1 mmHg
Melt Point(°C)278 - 282 °C / 532.4 - 539.6 °F

Safety and Hazards(GHS)

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References

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57. Claire Kelly,Neel Bhuva,Mark Harrison,Andrew Buckley,Mark Saunders.  (2013-04-16)  Use of raltitrexed as an alternative to 5-fluorouracil and capecitabine in cancer patients with cardiac history..  European journal of cancer (Oxford, England : 1990),  49  ((10)): (2303-2310).  [PMID:23583220]
58. Hiroaki Furuyama,Hiroaki Fuji,Shinya Okumura,Tatsuhito Nishigori,Yoshio Kadokawa,Masato Kondo,Takafumi Machimoto,Yoshito Asao,Tsunehiro Yoshimura.  (2013-07-19)  [A case of recurrent colon cancer developed thrombosis in superior mesenteric vein after chemotherapy]..  Gan to kagaku ryoho. Cancer & chemotherapy,  40  ((5)): (659-661).  [PMID:23863595]
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60. Qing Lin,Yunpeng Cai,Minglu Yuan,Lin Ma,Mingfeng Qiu,Jing Su.  (2014-09-19)  Development of a 5-fluorouracil-loaded PLGA microsphere delivery system by a solid-in-oil-in-hydrophilic oil (S/O/hO) novel method for the treatment of tumors..  Oncology reports,  32  ((6)): (2405-2410).  [PMID:25231485]
61. Davide Esposito,Elvira Crescenzi,Vinay Sagar,Fabrizio Loreni,Annapina Russo,Giulia Russo.  (2014-12-05)  Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP..  Oncotarget,  ((22)): (11737-11751).  [PMID:25473889]
62. Jian Gu,Xiaohui Mao,Cong Li,Huafei Ao,Xizhi Yang.  (2015-02-14)  A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil..  The Annals of otology, rhinology, and laryngology,  124  ((7)): (561-566).  [PMID:25678670]
63. Xiang Chen,Xin Li,Baohong Zhao,Dehao Shang,Ming Zhong,Chunfu Deng,Xinshan Jia.  (2015-02-28)  Dormancy activation mechanism of oral cavity cancer stem cells..  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,  36  ((7)): (5551-5559).  [PMID:25722113]
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