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R-Palmitoyl-(2-methyl) Ethanolamide

Item Number
R351090
Grouped product items
SKUSizeAvailabilityPrice Qty
R351090-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$26.90
R351090-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$50.90
Discover R-Palmitoyl-(2-methyl) Ethanolamide by Aladdin Scientific in for only $26.90. Available - in Ligands at Aladdin Scientific. a metabolically stable analog of palmitoyl ethanolamide Tags: .

Basic Description

Synonyms179951-56-5|Palmitic monoisopropanolamide, (R)-|R-Palmitoyl-(2-methyl) Ethanolamide|N-[(2R)-2-hydroxypropyl]hexadecanamide|UNII-3438DY3589|N-(2R-Hydroxypropyl)-hexadecanamide|3438DY3589|Hexadecanamide, N-[(2R)-2-hydroxypropyl]-|HEXADECANAMIDE, N-((2R)-2-H
Storage TempStore at 2-8°C
Shipped InWet ice
Description

A metabolically stable analog of the anti-inflammatory cannabinoid, palmitoyl ethanolamide (PEA) which is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro. RP-2ME is a synthetic analog of PEA which incorporates an (R)-methyl group vicinal to the alcohol on the ethanolamine moiety. RP-2ME inhibits FAAH-mediated hydrolysis of AEA by 54% at a concentration of 100 μM. It also has weak CB receptor affinity, in that 100 μM inhibits agonist binding (1 nM CP55940 or WIN55212-2) only 26% and 15.5% at the human CB1 and CB2 receptors, respectively.

Names and Identifiers

IUPAC Name N-[(2R)-2-hydroxypropyl]hexadecanamide
INCHI InChI=1S/C19H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19(22)20-17-18(2)21/h18,21H,3-17H2,1-2H3,(H,20,22)/t18-/m1/s1
InChi Key VQNMGLLFMPXVFN-GOSISDBHSA-N
Canonical SMILES CCCCCCCCCCCCCCCC(=O)NCC(C)O
Isomeric SMILES CCCCCCCCCCCCCCCC(=O)NC[C@@H](C)O
PubChem CID 18395309
Molecular Weight 313.5

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